Zobrazeno 1 - 10
of 430
pro vyhledávání: '"Xiao-Jun Du"'
Autor:
Yu Zhang, Jing-Jing Li, Rui Xu, Xin-Pei Wang, Xin-Yi Zhao, Yuan Fang, Yu-Peng Chen, Shan Ma, Xiao-Hui Di, Wei Wu, Gang She, Zheng-Da Pang, Yi-Dong Wang, Xing Zhang, Wenjun Xie, Xiu-Ling Deng, Xiao-Jun Du, Yi Zhang
Publikováno v:
Redox Biology, Vol 68, Iss , Pp 102944- (2023)
Aims: Endothelial dysfunction plays a pivotal role in atherosclerosis, but the detailed mechanism remains incomplete understood. Nogo-B is an endoplasmic reticulum (ER)-localized protein mediating ER-mitochondrial morphology. We previously showed end
Externí odkaz:
https://doaj.org/article/66907925c4c1495da7a001e602e430cf
Autor:
Yi Zhang, Xiao-Zhen Ma, Xin-Yi Zhao, Jing-Jing Li, Shan Ma, Zheng-Da Pang, Jing Xu, Xiao-Jun Du, Xiu-Ling Deng, Jun-Hong Wang
Publikováno v:
Heliyon, Vol 9, Iss 4, Pp e14823- (2023)
Type 2 diabetes mellitus (T2DM) is characterized by chronic low-grade systemic inflammation. Tissue infiltration by monocyte migration contributes to the pathogenesis of vascular complications in T2DM. We studied the role of intermediate-conductance
Externí odkaz:
https://doaj.org/article/fa0d579649c7403cbc02094a04ce163a
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Mitochondrial dysfunction is implicated in the development of cardiomyopathy and heart failure. Transcription of mitochondrial DNA (mtDNA) encoded genes and subsequent protein synthesis are tightly regulated by nuclear DNA (nDNA) encoded
Externí odkaz:
https://doaj.org/article/a669fb739bc04786807a0a11eda0b73a
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundCardiac rupture (CR) and left ventricular thrombus (LVT) remain important complications of acute myocardial infarction (MI), and they are currently regarded as independent events. We explored the pathogenetic link between CR and LVT by inve
Externí odkaz:
https://doaj.org/article/e18e6dbc2bbc4417ac1fd0dda9bf3e70
Publikováno v:
BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Cardiac rupture (CR) is a fatal complication of ST-elevation myocardial infarction (STEMI) with its incidence markedly declined in the recent decades. However, clinical features of CR patients now and the effect of reperfusion the
Externí odkaz:
https://doaj.org/article/72ee19b9f0d64bef9502318ff711a02e
Autor:
Qun Lu, Ruo-Chen Zhang, Shu-Ping Chen, Tao Li, Ya Wang, Yan-Bo Xue, Jing Liu, Xiu Han, Yi-Dan Su, Ling Bai, Xiao-Jun Du, Ai-Qun Ma
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Aim: The aim of present study is to evaluate the diagnostic and prognostic value of plasma galectin 3 (Gal-3) for HF originating from different causes.Methods: We investigated the plasma levels and expression of Gal-3 in cardiac tissues in two transg
Externí odkaz:
https://doaj.org/article/85e3c27826624e11a0c1327dbd55aaa8
Autor:
Aowen Zhuang, Anna C. Calkin, Shannen Lau, Helen Kiriazis, Daniel G. Donner, Yingying Liu, Simon T. Bond, Sarah C. Moody, Eleanor A.M. Gould, Timothy D. Colgan, Sergio Ruiz Carmona, Michael Inouye, Thomas Q. de Aguiar Vallim, Elizabeth J. Tarling, Gregory A. Quaife-Ryan, James E. Hudson, Enzo R. Porrello, Paul Gregorevic, Xiao-Ming Gao, Xiao-Jun Du, Julie R. McMullen, Brian G. Drew
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102537- (2021)
Summary: Long non-coding RNAs (lncRNAs) have been demonstrated to influence numerous biological processes, being strongly implicated in the maintenance and physiological function of various tissues including the heart. The lncRNA OIP5-AS1 (1700020I14
Externí odkaz:
https://doaj.org/article/453eb2947cf84c34a110e74e3feab67a
Autor:
Harikrishnan K.N., Jun Okabe, Prabhu Mathiyalagan, Abdul Waheed Khan, Sameer A. Jadaan, Gulcan Sarila, Mark Ziemann, Ishant Khurana, Scott S. Maxwell, Xiao-Jun Du, Assam El-Osta
Publikováno v:
iScience, Vol 17, Iss , Pp 288-301 (2019)
Summary: In the heart, primary microRNA-208b (pri-miR-208b) and Myheart (Mhrt) are long non-coding RNAs (lncRNAs) encoded by the cardiac myosin heavy chain genes. Although preclinical studies have shown that lncRNAs regulate gene expression and are p
Externí odkaz:
https://doaj.org/article/9b10dc8224044e069e8b71f22e306dbf
Autor:
Cheng Xue Qin, Lauren T. May, Renming Li, Nga Cao, Sarah Rosli, Minh Deo, Amy E. Alexander, Duncan Horlock, Jane E. Bourke, Yuan H. Yang, Alastair G. Stewart, David M. Kaye, Xiao-Jun Du, Patrick M. Sexton, Arthur Christopoulos, Xiao-Ming Gao, Rebecca H. Ritchie
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
G Protein-Coupled Receptors (GPCRs) can adopt different conformations, each linked to distinct cellular outcomes. Here the authors show that compound 17b, a novel agonist of the GPCR family member FPR, robustly activates cardioprotective but not detr
Externí odkaz:
https://doaj.org/article/662689059cf2432b82994c3add7656fb
Autor:
David Braig, Tracy L. Nero, Hans-Georg Koch, Benedict Kaiser, Xiaowei Wang, Jan R. Thiele, Craig J. Morton, Johannes Zeller, Jurij Kiefer, Lawrence A. Potempa, Natalie A. Mellett, Luke A. Miles, Xiao-Jun Du, Peter J. Meikle, Markus Huber-Lang, G. Björn Stark, Michael W. Parker, Karlheinz Peter, Steffen U. Eisenhardt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
C-reactive protein is a pentameric protein secreted by the liver in response to injury and infection. Here Braiget al. show that conformational changes in CRP on the surface of monocyte-derived microvesicles enable binding of complement C1q and lead
Externí odkaz:
https://doaj.org/article/128f34d5a0f648b598b01c6bc5aab5a5