Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Xiao-Jie Yao"'
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Background: Post-stroke dysphagia (PSD) affects the quality of life in stroke patients, impairs their rehabilitation ability, and causes other complications following stroke. Currently, there is currently some understanding of PSD risk factors, but i
Externí odkaz:
https://doaj.org/article/ef3cfa4a93b34c26adba0906966051cc
Autor:
Sachdev S. Sidhu, Brian K. Kobilka, Xin Chen, Li-Yin Huang, Arun K. Shukla, Austin N. Oleskie, Minjung Choi, Sheng Li, Ling Ling Gu, Anthony A. Kossiakoff, Jiang Qian, Gerwin Westfield, Rosana I. Reis, Robert J. Lefkowitz, Shohei Koide, Alem W. Kahsai, Georgios Skiniotis, Jin Ming Shan, Adi Blanc, Prachi Tripathi-Shukla, Pawel A. Penczek, Cui Rong Liang, Rachel Hanna, Anne M. Dosey, Bjoern U. Klink, Xiao Jie Yao, Kunhong Xiao, Min Su, Virgil L. Woods
Publikováno v:
Nature
Single-particle electron microscopy and hydrogen–deuterium exchange mass spectrometry are used to characterize the structure and dynamics of a G-protein-coupled receptor–arrestin complex. Much has been learned about the structure of G-protein-cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f682eb622e9146fca04b1ae7ebd9fa7d
https://doi.org/10.1038/nature13430
https://doi.org/10.1038/nature13430
Publikováno v:
Materials Science Forum. :1045-1048
Recent experiments have indicated that TiO2 co-doped with cerium (Ce) and nitrogen (N) may show enhanced photocatalytic activity in the visible region with respect to TiO2 doped only with Ce. Prompted by these findings, we have investigated Ce-N co-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::825a492acfa1734b6af63f6ddb27ab7a
https://doi.org/10.4028/www.scientific.net/msf.675-677.1045
https://doi.org/10.4028/www.scientific.net/msf.675-677.1045
Autor:
Gisselle Vélez Ruiz, Matthew R. Whorton, Xiao Jie Yao, Xavier Deupi, Brian T. DeVree, Brian K. Kobilka, Søren G. F. Rasmussen, Roger K. Sunahara
Publikováno v:
Proceedings of the National Academy of Sciences. 106:9501-9506
G protein-coupled receptors (GPCRs) mediate the majority of physiologic responses to hormones and neurotransmitters. However, many GPCRs exhibit varying degrees of agonist-independent G protein activation. This phenomenon is referred to as basal or c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdbd95bf15fff5e555c06a75e0eee4d
https://doi.org/10.1073/pnas.0811437106
https://doi.org/10.1073/pnas.0811437106
Autor:
Daniel M. Rosenbaum, Xiao-Jie Yao, Brian K. Kobilka, Vadim Cherezov, Raymond C. Stevens, William I. Weis, Tong Sun Kobilka, Hee Jung Choi, Søren G. F. Rasmussen, Foon Sun Thian, Michael A. Hanson
Publikováno v:
Science. 318:1266-1273
The β 2 -adrenergic receptor (β 2 AR) is a well-studied prototype for heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptors (GPCRs) that respond to diffusible hormones and neurotransmitters. To overcome the structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b938b46e684682476237992bd34baa
https://doi.org/10.1126/science.1150609
https://doi.org/10.1126/science.1150609
Autor:
Venkata R. P. Ratnala, Gayathri Swaminath, David L. Farrens, Charles Parnot, Brian K. Kobilka, Xiao-Jie Yao, Xavier Deupi
Publikováno v:
Nature Chemical Biology. 2:417-422
G protein-coupled receptors (GPCRs) regulate a wide variety of physiological functions in response to structurally diverse ligands ranging from cations and small organic molecules to peptides and glycoproteins. For many GPCRs, structurally related li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1798230fa8a774c2aa1c02f36dee1a6d
https://doi.org/10.1038/nchembio801
https://doi.org/10.1038/nchembio801
Autor:
Chris S. Gandhi, Bruce E. Cohen, Xiao-Jie Yao, Lily Yeh Jan, Gayathri Swaminath, Yuh Nung Jan, Arnd Pralle, Brian K. Kobilka, Ehud Y. Isacoff
Publikováno v:
Proceedings of the National Academy of Sciences. 102:965-970
The usefulness of fluorescence in studying protein motions derives from its sensitivity, kinetic resolution, and compatibility with both live cells and physiological assays. Recent advances in microscopy and membrane protein purification have permitt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcc0a51ad2eac8f34b7172de8169c9e
https://doi.org/10.1073/pnas.0409469102
https://doi.org/10.1073/pnas.0409469102
G protein-coupled receptors (GPCRs) comprise a large family of seven-helix transmembrane proteins which regulate cellular signaling by sensing light, ligands, and binding proteins. The GPCR activation process, however, is not a simple on-off switch;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d31a7a5a5f03de8f1627164d98381ef
https://europepmc.org/articles/PMC3213290/
https://europepmc.org/articles/PMC3213290/
Autor:
Roger K. Sunahara, Juan Jose Fung, Brian K. Kobilka, Gisselle A. Vélez-Ruiz, Brian T. DeVree, Xiao Jie Yao, Leonardo Pardo, Xavier Deupi
Publikováno v:
The EMBO Journal
The beta(2)-adrenoceptor (beta(2)AR) was one of the first Family A G protein-coupled receptors (GPCRs) shown to form oligomers in cellular membranes, yet we still know little about the number and arrangement of protomers in oligomers, the influence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3e7b87829c70e0901bbca4aed4bb5c
https://pubmed.ncbi.nlm.nih.gov/19763081
https://pubmed.ncbi.nlm.nih.gov/19763081
Autor:
Samuel Bockenhauer, Michael P. Bokoch, Alexandre Fürstenberg, Roger K. Sunahara, Brian T. DeVree, Brian K. Kobilka, W. E. Moerner, Quan Wang, Xiao Jie Yao
Publikováno v:
Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest.
The Anti-Brownian ELectrokinetic (ABEL) trap uses voltage feedback to electrokinetically cancel the Brownian motion of single particles in solution in microfluidic geometries. This allows trapping of single high density lipoprotein (HDL) particles fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abdf66c899f6707a4edd9107e145a84b
https://doi.org/10.1364/ls.2009.jwc16
https://doi.org/10.1364/ls.2009.jwc16