Zobrazeno 1 - 10 of 36 pro vyhledávání: '"Xiao-Jiao Huo"'
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Akademický článek
The anti-diabetic drug metformin protects against chemotherapy-induced peripheral neuropathy in a mouse model.
Autor: Qi-Liang Mao-Ying, Annemieke Kavelaars, Karen Krukowski, Xiao-Jiao Huo, Wenjun Zhou, Theodore J Price, Charles Cleeland, Cobi J Heijnen
Publikováno v: PLoS ONE, Vol 9, Iss 6, p e100701 (2014)
Chemotherapy-induced peripheral neuropathy (CIPN) characterized by loss of sensory sensitivity and pain in hands and feet is the major dose-limiting toxicity of many chemotherapeutics. At present, there are no FDA-approved treatments for CIPN. The an
Externí odkaz: https://doaj.org/article/44e74bf2bc20480e95f8aa91a8084fec
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5
Interleukin-10 resolves pain hypersensitivity induced by cisplatin by reversing sensory neuron hyperexcitability
Autor: Geoffroy Laumet, Cobi J. Heijnen, Robert Dantzer, Xiao Jiao Huo, Annemieke Kavelaars, Edgar T. Walters, Alexis Bavencoffe, Jules D. Edralin
Publikováno v: Pain
Understanding the mechanisms that drive transition from acute to chronic pain is essential to identify new therapeutic targets. The importance of endogenous resolution pathways acting as a "brake" to prevent development of chronic pain has been large
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439ff08aa4da024e1e8053c327655aa2
https://doi.org/10.1097/j.pain.0000000000001921
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6
Safety and Efficacy of Combination Maintenance Therapy with Ixazomib and Lenalidomide in Patients with Posttransplant Myeloma
Autor: Krina K. Patel, Jatin J. Shah, Lei Feng, Hans C. Lee, Elisabet M. Manasanch, Jasper Olsem, Ashley Morphey, Xiao Jiao Huo, Sheeba K. Thomas, Qaiser Bashir, Muzaffar H. Qazilbash, Donna M. Weber, Robert Z. Orlowski
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 28(7)
Purpose: In this study, the addition of ixazomib to lenalidomide maintenance post-autologous stem cell transplant (ASCT) in 64 patients with newly diagnosed multiple myeloma was evaluated on the basis of the observed benefit of lenalidomide-only main
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835777024ec3b14acb7b02f516ceb305
https://pubmed.ncbi.nlm.nih.gov/34992070
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7
Chemotherapy accelerates age-related development of tauopathy and results in loss of synaptic integrity and cognitive impairment
Autor: Angie C.A. Chiang, Annemieke Kavelaars, Cobi J. Heijnen, Xiao Jiao Huo
Publikováno v: Brain Behav Immun
Cancer and its treatment are associated with neurotoxic side effects, including cognitive dysfunction, altered functional connectivity in the brain and structural abnormalities in white matter. There is evidence that cancer and its treatment can acce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cf06dfda131db40b8047ab614fc929
https://doi.org/10.1016/j.bbi.2019.04.005
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8
Safety and Efficacy of Combination Maintenance Therapy with Ixazomib and Lenalidomide in Post-Transplant Myeloma Patients
Autor: Elisabet E. Manasanch, Donna M. Weber, Muzaffar H. Qazilbash, Robert Z. Orlowski, Krina K. Patel, Hans C. Lee, Qaiser Bashir, Jatin J. Shah, Sheeba K. Thomas, Ashley Morphey, Jasper B. Olsem, Xiao Jiao Huo, Lei Feng
Publikováno v: Blood. 138:4774-4774
Backrground: Several randomized controlled clinical trials have demonstrated improved outcomes for newly diagnosed multiple myeloma (NDMM) patients who were treated with lenalidomide as maintenance therapy after autologous stem cell transplant (ASCT)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27933ea36fdd6163d379be57f228e1fc
https://doi.org/10.1182/blood-2021-151950
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9
Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy
Autor: Pooja Singhmar, Fang C Mei, Annemieke Kavelaars, Yan Li, Xiao Jiao Huo, Xiaodong Cheng, Patrick M. Dougherty, Cobi J. Heijnen
Publikováno v: Pain. 159:884-893
Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect of cancer treatment that significantly compromises quality of life of cancer patients and survivors. Identification of targets for pharmacological intervention to prevent or rev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adc9a8825336617c7c9db91dc69a32c
https://doi.org/10.1097/j.pain.0000000000001160
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10
Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment
Autor: Annemieke Kavelaars, Xiao Jiao Huo, Matthew Jarpe, Jiacheng Ma, Cobi J. Heijnen
Publikováno v: Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-14 (2018)
Chemotherapy-induced cognitive impairment (CICI) is a commonly reported neurotoxic side effect of chemotherapy, occurring in up to 75% cancer patients. CICI manifests as decrements in working memory, executive functioning, attention, and processing s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a997eb8273e02663233999675e1f2e
http://europepmc.org/articles/PMC6166273
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