Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Xiao-Hu Fan"'
1
Akademický článek
Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity
Autor: Yan Sun, Xiu-Na Yang, Shuang-Shuang Yang, Yi-Zhu Lyu, Bing Zhang, Kai-Wen Liu, Na Li, Jia-Chen Cui, Guang-Xiang Huang, Cheng-Lin Liu, Jie Xu, Jian-Qing Mi, Zhu Chen, Xiao-Hu Fan, Sai-Juan Chen, Shuo Chen
Publikováno v: Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Ligand-induced receptor dimerization or oligomerization is a widespread mechanism for ensuring communication specificity, safeguarding receptor activation, and facilitating amplification of signal transduction across the cellular membrane. H
Externí odkaz: https://doaj.org/article/c6028438f67a42c18a6b2a7dc87dd6ff
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3
Akademický článek
Four-year follow-up of LCAR-B38M in relapsed or refractory multiple myeloma: a phase 1, single-arm, open-label, multicenter study in China (LEGEND-2)
Autor: Wan-Hong Zhao, Bai-Yan Wang, Li-Juan Chen, Wei-Jun Fu, Jie Xu, Jie Liu, Shi-Wei Jin, Yin-Xia Chen, Xing-Mei Cao, Yun Yang, Yi-Lin Zhang, Fang-Xia Wang, Peng-Yu Zhang, Bo Lei, Liu-Fang Gu, Jian-Li Wang, Hui Zhang, Ju Bai, Yan Xu, Han Zhu, Juan Du, Hua Jiang, Xiao-Hu Fan, Jian-Yong Li, Jian Hou, Zhu Chen, Wang-Gang Zhang, Jian-Qing Mi, Sai-Juan Chen, Ai-Li He
Publikováno v: Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-12 (2022)
Abstract Background LCAR-B38M is a chimeric antigen receptor T cell product with two binding domains targeting B cell maturation antigen. Our previous reports showed a remarkable efficacy of LCAR-B38M in patients with relapsed/refractory multiple mye
Externí odkaz: https://doaj.org/article/680bd4fe1f994d6db669554110364f34
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4
Akademický článek
A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma
Autor: Wan-Hong Zhao, Jie Liu, Bai-Yan Wang, Yin-Xia Chen, Xing-Mei Cao, Yun Yang, Yi-Lin Zhang, Fang-Xia Wang, Peng-Yu Zhang, Bo Lei, Liu-Fang Gu, Jian-Li Wang, Nan Yang, Ru Zhang, Hui Zhang, Ying Shen, Ju Bai, Yan Xu, Xu-Geng Wang, Rui-Li Zhang, Li-Li Wei, Zong-Fang Li, Zhen-Zhen Li, Yan Geng, Qian He, Qiu-Chuan Zhuang, Xiao-Hu Fan, Ai-Li He, Wang-Gang Zhang
Publikováno v: Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-8 (2018)
Abstract Background Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a dual epitope-binding CAR T cell therapy directed against 2 distinct
Externí odkaz: https://doaj.org/article/465fd456636849ce93bd874e19984b0a
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5
Management of cytokine release syndrome related to CAR-T cell therapy
Autor: Wanggang Zhang, Rui-Li Zhang, Liufang Gu, Hongli Chen, Xing-Mei Cao, Bo Lei, Yi-Lin Zhang, Li-Li Wei, Ju Bai, Wan-Hong Zhao, Aili He, Yun Yang, Yin-Xia Chen, Jie Liu, Xiao-Hu Fan, Qiu-Chuan Zhuang, Fang-Xia Wang, Pengyu Zhang, Baiyan Wang
Publikováno v: Frontiers of Medicine. 13:610-617
Chimeric antigen receptor T (CAR-T) cell therapy is a novel cellular immunotherapy that is widely used to treat hematological malignancies, including acute leukemia, lymphoma, and multiple myeloma. Despite its remarkable clinical effects, this therap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77681e549e49371ee0535f9fd5611869
https://doi.org/10.1007/s11684-019-0714-8
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6
Geomagnetic Field Simulation in Hardware-in-the-Loop Simulation System for Geomagnetic Navigation
Autor: Ning Liu, Jian yong Wang, Li guo Xu, Xiao hu Fan, Zhi feng Lyu
Publikováno v: Advances in Intelligent Systems and Computing ISBN: 9789811618420
Geomagnetic navigation is a navigation technique by using geomagnetic feature, and it has wide application prospects. But the reliability of its technologies remains to be verified. This paper reports the construction of the hardware-in-the-loop simu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ff11f908efb9d72b466aeebfbfde467
https://doi.org/10.1007/978-981-16-1843-7_22
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7
A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma
Autor: Zongfang Li, Wanggang Zhang, Rui-Li Zhang, Yan Geng, Qiu-Chuan Zhuang, Yun Yang, Baiyan Wang, Hui Zhang, Yin-Xia Chen, Jie Liu, Zhenzhen Li, Qian He, Ju Bai, Li-Li Wei, Pengyu Zhang, Jianli Wang, Liufang Gu, Xing-Mei Cao, Nan Yang, Yi-Lin Zhang, Xiao-Hu Fan, Ying Shen, Xu-Geng Wang, Yan Xu, Bo Lei, Fang-Xia Wang, Ru Zhang, Wan-Hong Zhao, Aili He
Publikováno v: Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-8 (2018)
Journal of Hematology & Oncology
Background Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a dual epitope-binding CAR T cell therapy directed against 2 distinct B cell ma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd6e3b75bbb9aca36cc235143205f45
http://link.springer.com/article/10.1186/s13045-018-0681-6
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8
Chimeric Antigen Receptor T Cell Therapy in the Relapsed or Refractory Multiple Myeloma with Extramedullary Disease--a Single Institution Observation in China
Autor: Jianli Wang, Wanggang Zhang, Frank Xiao-Hu Fan, Xing-Mei Cao, Baiyan Wang, Yun Yang, Yin-Xia Chen, Wan-Hong Zhao, Aili He, Liufang Gu, Bo Lei, Jie Liu, Yi-Lin Zhang, Pengyu Zhang, Fang-Xia Wang
Publikováno v: Blood. 136:6-6
Background: Extramedullary disease (EMD) is characterized as the presence of myeloma cells invasion outside the bone marrow in a patient with multiple myeloma (MM), it may be found 6%~8% in de novo patients, and 10% to 30% in relapsed or refractory (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5666cbc5acb03b86f11a2f8780ce791d
https://doi.org/10.1182/blood-2020-140243
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9
Application of Brushless Motor Speed Control System in Wave Power Generation Technology
Autor: Xiao-hu Fan, Yu-ying Zhou, Zhou Yan
Publikováno v: Communications in Computer and Information Science ISBN: 9789811064623
In the development of new energy, a new type of marine gyro power plant has a higher wave energy conversion efficiency in the field of wave energy, the key component of which is the gyroscope speed control system, but designing a motor system for a h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::687a7d59f53e40658ee830cd9cb667ce
https://doi.org/10.1007/978-981-10-6463-0_56
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10
A Comparison of Two Typical Local Feature Matching Algorithm: SIFT and MSER
Autor: Xiao Cui, Xiao Liu, Xiao Cun Jiang, Xiao Hu Fan, Tao Tang
Publikováno v: Applied Mechanics and Materials. :4119-4122
Scale invariant feature transform matching algorithm and Maximally Stable Extremal Regions matching algorithm have been widely used because of their good performance. The two local feature matching algorithms were compared through numbers of experime
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a37015d20afec320a45bd029c4b2dc6d
https://doi.org/10.4028/www.scientific.net/amm.687-691.4119
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