Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Xiao-Fang Mao"'
Autor:
Evhy Apryani, Usman Ali, Zi-Ying Wang, Hai-Yun Wu, Xiao-Fang Mao, Khalil Ali Ahmad, Xin-Yan Li, Yong-Xiang Wang
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Cinobufagin is the major bufadienolide of Bufonis venenum (Chansu), which has been traditionally used for the treatment of chronic pain especially cancer pain. The current study aimed to evaluate its antinociceptive effects in bon
Externí odkaz:
https://doaj.org/article/f7c3b736aa254cfb95e44fdcd7552351
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-19 (2019)
Abstract Background The G protein-coupled receptor 40 (GPR40), broadly expressed in various tissues such as the spinal cord, exerts multiple physiological functions including pain regulation. This study aimed to elucidate the mechanisms underlying GP
Externí odkaz:
https://doaj.org/article/5fffad12cef749cc9af629f66c19a36b
Publikováno v:
Biochemical and Biophysical Research Communications. 530:494-499
Objectives To assess the protective effect of the glucagon-like peptide-1 receptor (GLP-1R) agonist morroniside against neuropathic pain and its downstream mechanisms of activating microglial GLP-1R/interleukin-10 (IL-10)/β-endorphin antinociceptive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad01db39ca1849b040e10113c8c01657
https://doi.org/10.1016/j.bbrc.2020.05.080
https://doi.org/10.1016/j.bbrc.2020.05.080
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 125, Iss, Pp 109898-(2020)
Electroacupuncture produces analgesia in chronic pain patients and animal models of pain hypersensitivity. The current study aims to illustrate the mechanisms underlying electroacupuncture-attenuated neuropathic pain. Neuropathic rats, induced by tig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664009f379032563ec6d719e202b5a9e
http://www.sciencedirect.com/science/article/pii/S0753332220300883
http://www.sciencedirect.com/science/article/pii/S0753332220300883
Autor:
Usman Ali, Hai-Yun Wu, Zi-Ying Wang, Evhy Apryani, Xiao-Fang Mao, Xin-Yan Li, Khalil Ali Ahmad, Yong-Xiang Wang
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Cinobufagin is the major bufadienolide of Bufonis venenum (Chansu), which has been traditionally used for the treatment of chronic pain especially cancer pain. The current study aimed to evaluate its antinociceptive effects in bone cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55c59ac55ff1e3ed5e451d6a020bd40
https://doi.org/10.1186/s12974-019-1616-z
https://doi.org/10.1186/s12974-019-1616-z
Autor:
Xue-Qi Tang, Yong-Ming Qiu, Li-Xin Jiang, Xin-Yan Li, Jiong Dai, Yong-Xiang Wang, Xiao-Fang Mao, Qiao-Qiao Han
Publikováno v:
Biochemical and Biophysical Research Communications. 505:113-118
The transcription factor Gli2 plays crucial roles in the transduction of Hedgehog (Hh) signals, yet the mechanisms that control Gli2 degradation remain unclear. Here we have identified the eubiquitinating enzyme otubain2 (OTUB2) as a regulator of Gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b1585708abe03f07bf565d1ce40377
https://doi.org/10.1016/j.bbrc.2018.09.071
https://doi.org/10.1016/j.bbrc.2018.09.071
Autor:
Yong-Xiang Wang, Xin-Yan Li, Usman Ali, Evhy Apryani, Hao Liu, Xue-Qi Tang, Xiao-Fang Mao, Hai-Yun Wu
Publikováno v:
Brain, Behavior, and Immunity. 73:504-519
Interleukin 10 (IL-10) is antinociceptive in various animal models of pain without induction of tolerance, and its mechanism of action was generally believed to be mediated by inhibition of neuroinflammation. Here we reported that intrathecal IL-10 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c9b7075533611fdc6548f82e0673ee
https://doi.org/10.1016/j.bbi.2018.06.015
https://doi.org/10.1016/j.bbi.2018.06.015
Publikováno v:
Molecular Pharmacology. 91:451-463
Recent discoveries established that activation of glucagon-like peptide-1 receptors (GLP-1Rs) mediates neuroprotection and antinociception through microglial β-endorphin expression. This study aimed to explore the underlying signaling mechanisms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68b058572e200255ca48396014ca2977
https://doi.org/10.1124/mol.116.107102
https://doi.org/10.1124/mol.116.107102
Autor:
Qian Huang1, Xiao-Fang Mao1, Hai-Yun Wu1, Teng-Fei Li1, Ming-Li Sun1, Hao Liu1, Yong-Xiang Wang1 yxwang@sjtu.edu.cn, Huang, Qian2 (AUTHOR), Mao, Xiao-Fang2 (AUTHOR), Wu, Hai-Yun2 (AUTHOR), Li, Teng-Fei2 (AUTHOR), Sun, Ming-Li2 (AUTHOR), Liu, Hao2 (AUTHOR), Wang, Yong-Xiang2 (AUTHOR)
Publikováno v:
Journal of Neuroinflammation. 8/30/2016, Vol. 13, p1-18. 18p.
Autor:
Meng-Jing Zhao, Xin-Yan Li, Yong-Xiang Wang, Xue-Qi Tang, Muhammad Zaeem Ahsan, Xiao-Fang Mao, Evhy Apryani
Publikováno v:
European Journal of Pharmacology. 876:173062
Dezocine is an opioid analgesic widely used in China, occupying over 45% of the domestic market of opioid analgesics. We have recently demonstrated that dezocine produced mechanical antiallodynia and thermal antihyperalgesia through spinal μ-opioid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05267535bed06e54ff932679960229da
https://doi.org/10.1016/j.ejphar.2020.173062
https://doi.org/10.1016/j.ejphar.2020.173062