Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Xiao Yi Zeng"'
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Albiflorin (AF) is a small molecule (MW 481) isolated from Paeoniae radix, a plant used as a remedy for various conditions with pathogenesis shared by metabolic diseases. Reported here is our characterization of its therapeutic profiles in three mous
Externí odkaz:
https://doaj.org/article/bca2b962272047c9aec86daf43ac15ba
Autor:
James R. Krycer, Ciana Diskin, Marin E. Nelson, Xiao-Yi Zeng, Daniel J. Fazakerley, David E. James
Publikováno v:
BioTechniques, Vol 64, Iss 1, Pp 27-29 (2018)
Research into cellular metabolism has become more high-throughput, with typical cell-culture experiments being performed in multiwell plates (microplates). This format presents a challenge when trying to collect gaseous products, such as carbon dioxi
Externí odkaz:
https://doaj.org/article/8585945efbd84c4a9807339ed7cf63a5
Autor:
Xiu Zhou, Xiao-Yi Zeng, Hao Wang, Songpei Li, Eunjung Jo, Charlie C L Xue, Minjia Tan, Juan C Molero, Ji-Ming Ye
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107231 (2014)
Our recent study (referred as Study 1) showed that the triterpenoid oleanolic acid (OA) was able to produce a sustained correction of hyperglycemia beyond treatment period in type 2 diabetes (T2D) mice with liver as a responsible site. To follow up t
Externí odkaz:
https://doaj.org/article/c413cc33a0854795a8d4302e82d4feb0
Autor:
Tristan J Iseli, Nigel Turner, Xiao-Yi Zeng, Gregory J Cooney, Edward W Kraegen, Sheng Yao, Yang Ye, David E James, Ji-Ming Ye
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62309 (2013)
We recently showed that bitter melon-derived triterpenoids (BMTs) activate AMPK and increase GLUT4 translocation to the plasma membrane in vitro, and improve glucose disposal in insulin resistant models in vivo. Here we interrogated the mechanism by
Externí odkaz:
https://doaj.org/article/d67835f8a4ae4b2bb01009436d88b823
Autor:
Xiao-Yi Zeng, Yi-Ping Wang, James Cantley, Tristan J Iseli, Juan Carlos Molero, Bronwyn D Hegarty, Edward W Kraegen, Yang Ye, Ji-Ming Ye
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42115 (2012)
The present study investigated the chronic efficacy of oleanolic acid (OA), a triterpenoid selected from our recent screening, on hyperglycemia in type-2 diabetic mice. C57BL/6J mice were fed a high-fat diet followed by low doses of streptozotocin to
Externí odkaz:
https://doaj.org/article/4846e6d2445b4bdd9e37c2b07c3cd66d
Autor:
Lu-Ping Ren, Stanley M H Chan, Xiao-Yi Zeng, D Ross Laybutt, Tristan J Iseli, Ruo-Qiong Sun, Edward W Kraegen, Gregory J Cooney, Nigel Turner, Ji-Ming Ye
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30816 (2012)
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress have been implicated in hepatic steatosis and insulin resistance. The present study investigated their roles in the development of hepatic steatosis and insulin resistance during de novo
Externí odkaz:
https://doaj.org/article/955ff7c56eb041cb93ac77a8900849de
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology
Frontiers in Pharmacology
Albiflorin (AF) is a small molecule (MW 481) isolated from Paeoniae radix, a plant used as a remedy for various conditions with pathogenesis shared by metabolic diseases. Reported here is our characterization of its therapeutic profiles in three mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e42edc104112b4efcb604be33e5155
https://www.frontiersin.org/article/10.3389/fphar.2019.01151/full
https://www.frontiersin.org/article/10.3389/fphar.2019.01151/full
Autor:
Xiao-Yi Zeng, Ruo-Qiong Sun, Eunjung Jo, Ji-Ming Ye, Stanley M H Chan, Terence P. Herbert, Daria Camera, Hao Wang, Juan C. Molero
Publikováno v:
The FASEB Journal. 30:2549-2556
The accumulation of unfolded proteins within the endoplasmic reticulum (ER) causes ER stress and activation of unfolded protein response (UPR). This response can trigger ER-associated degradation and autophagy, which clear unfolded proteins and resto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9717e2fb13f24103d3407e19fb37b6bc
https://doi.org/10.1096/fj.201500119
https://doi.org/10.1096/fj.201500119
Autor:
David E. James, Marin E. Nelson, Xiao-Yi Zeng, James R. Krycer, Ciana Diskin, Daniel J. Fazakerley
Publikováno v:
BioTechniques. 64:27-29
Research into cellular metabolism has become more high-throughput, with typical cell-culture experiments being performed in multiwell plates (microplates). This format presents a challenge when trying to collect gaseous products, such as carbon dioxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2da345d3ecc8c4ef0d7dfddf3c13e08
https://doi.org/10.2144/000114629
https://doi.org/10.2144/000114629
Autor:
Ali Mahzari, Stephen R. Robinson, Xiu Zhou, Jun Xu, Wen Tan, Songpei Li, Ji-Ming Ye, Xiao-Yi Zeng, Ross Vlahos
The present study investigated the efficacy of the hepatoprotective drug matrine (Mtr) for its new application for hepatosteatosis and associated disorders in glucose homeostasis. The study was performed in two nutritional models of hepatosteatosis i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ace1727b5ed72eba6795f88fbfd7da
https://europepmc.org/articles/PMC6289344/
https://europepmc.org/articles/PMC6289344/
