Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Xiao Rong Zeng"'
Autor:
Li-Ying Zhong, Xin-Rong Fan, Zhang-Jing Shi, Zhong-Cai Fan, Jian Luo, Na Lin, Ying-Cai Liu, Lin Wu, Xiao-Rong Zeng, Ji-Min Cao, Yan Wei
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Hyperpolarization-activated cyclic nucleotide-gated ion channels (HCN channels) are widely expressed in the central and peripheral nervous systems and organs, while their functions are not well elucidated especially in the sympathetic nerve. The pres
Externí odkaz:
https://doaj.org/article/19b6a4dbe44d4eb998fba80363dd81c7
Autor:
Xiao-Dong Zhang, Chun-Xia He, Jun Cheng, Jing Wen, Peng-Yun Li, Na Wang, Guang Li, Xiao-Rong Zeng, Ji-Min Cao, Yan Yang
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Background: We previously have proved that sodium tanshinone II-A sulfonate (DS-201), a derivative of traditional Chinese medicinal herb Danshen (Salvia miltiorrhiza), is an opener and vasodilator of BKCa channel in the vascular smooth muscle cells (
Externí odkaz:
https://doaj.org/article/a171a344bd704f20b39c6dc79b12d899
Autor:
Jun Cheng, Liang Mao, Jing Wen, Peng‐Yun Li, Na Wang, Xiao‐Qiu Tan, Xiao‐Dong Zhang, Xiao‐Rong Zeng, Liang Xu, Xian‐Ming Xia, Dong Xia, Kai He, Song Su, Hui Yao, Yan Yang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 9, Pp n/a-n/a (2016)
Background Large‐conductance calcium‐ and voltage‐activated potassium channels (BKCa channels) play important roles in the maintenance of vascular tone, and their dysregulation is associated with abnormal vascular relaxation and contraction. We
Externí odkaz:
https://doaj.org/article/393e505f1c9b42fcb23be9763da3df04
Autor:
Xiao-Dong, Zhang, Chun-Xia, He, Jun, Cheng, Jing, Wen, Peng-Yun, Li, Na, Wang, Guang, Li, Xiao-Rong, Zeng, Ji-Min, Cao, Yan, Yang
Publikováno v:
Frontiers in Pharmacology
Background: We previously have proved that sodium tanshinone II-A sulfonate (DS-201), a derivative of traditional Chinese medicinal herb Danshen (Salvia miltiorrhiza), is an opener and vasodilator of BKCa channel in the vascular smooth muscle cells (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5091eafdb779a6c513d49c11962ec857
https://pubmed.ncbi.nlm.nih.gov/29456510
https://pubmed.ncbi.nlm.nih.gov/29456510
Publikováno v:
Sheng li xue bao : [Acta physiologica Sinica]. 69(3)
This study was aimed to establish a method to create a stable planar lipid bilayer membranes (PLBMs), in which large conductance calcium-activated potassium channels (BK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2347a880d40cd94d592dc7664c9c6ed4
https://pubmed.ncbi.nlm.nih.gov/28638923
https://pubmed.ncbi.nlm.nih.gov/28638923
Autor:
Miao-Ling Li, Xiao-Rong Zeng, Wei-Zhong Wang, Wang Yangkai, Zhao-Tang Wu, Pei-Lei Jiao, Tan Xing
SummaryAims It has been demonstrated that neuroinflammation is associated with cardiovascular dysfunction. The phosphoinositide-3 kinase (PI3K) signaling in the rostral ventrolateral medulla (RVLM), a key region for sympathetic outflow, is upregulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc8309f6627d03c3d71591c8841fe7f
https://europepmc.org/articles/PMC6492662/
https://europepmc.org/articles/PMC6492662/
Autor:
Xiao-Rong Zeng, Yan Yang, Peng-Yun Li, Xiao-Qiu Tan, Ming Lei, Miaoling Li, Fang Cai, Zhi-Fei Liu, Jun Cheng
Publikováno v:
Biochemical and Biophysical Research Communications. 439:363-368
Large conductance Ca(2+)-activated K(+) channel (BKCa) is a potential target for coronary artery-relaxing medication, but its functional regulation is largely unknown. Here, we report that inositol trisphosphate (IP3) activated BKCa channels in isola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1a4b53ac83af881f7e96ef75e0466b
https://doi.org/10.1016/j.bbrc.2013.08.079
https://doi.org/10.1016/j.bbrc.2013.08.079
Propofol increases the Ca2+ sensitivity of BKCa in the cerebral arterial smooth muscle cells of mice
Publikováno v:
Acta Pharmacologica Sinica. 33:19-26
Aim: Propofol has the side effect of hypotension especially in the elderly and patients with hypertension. Previous studies suggest propofol-caused hypotension results from activation of large conductance Ca 2+ -sensitive K channels (BKCa). In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789015e8bbfb7b02519f67bc5aedfaf7
https://doi.org/10.1038/aps.2011.134
https://doi.org/10.1038/aps.2011.134
Publikováno v:
European Journal of Pharmacology. 656:27-32
Sodium tanshinone II-A sulfonate (DS-201) is a water-soluble derivative of tanshinone IIA, a main active constituent of Salvia miltiorrhiza which has been used for treatments of cardio- and cerebro-vascular diseases. DS-201 activates large conductanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af06f3926fe3482c4f7e4375ebf5241
https://doi.org/10.1016/j.ejphar.2011.01.028
https://doi.org/10.1016/j.ejphar.2011.01.028
Publikováno v:
Acta Pharmacologica Sinica. 30:166-174
Tetrandrine (Tet) is a Ca(2+) channel blocker and has antiarrhythmic effects. Less information exists with regard to the mechanisms underlying its antiarrhythmic action other than blocking Ca(2+) channels. In this study, the effects of Tet on the Na(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eac2490ce23c42c8a65c4566372dae7
https://doi.org/10.1038/aps.2008.23
https://doi.org/10.1038/aps.2008.23