Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Xiao Min Schebye"'
Autor:
Ornella Pagliano, Robert M. Morrison, Joe-Marc Chauvin, Hridesh Banerjee, Diwakar Davar, Quanquan Ding, Tokiyoshi Tanegashima, Wentao Gao, Saranya R. Chakka, Richelle DeBlasio, Ava Lowin, Kevin Kara, Mignane Ka, Bochra Zidi, Rada Amin, Itay Raphael, Shuowen Zhang, Simon C. Watkins, Cindy Sander, John M. Kirkwood, Marcus Bosenberg, Ana C. Anderson, Vijay K. Kuchroo, Lawrence P. Kane, Alan J. Korman, Arvind Rajpal, Sean M. West, Minhua Han, Christine Bee, Xiaodi Deng, Xiao Min Schebye, Pavel Strop, Hassane M. Zarour
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
T cell immunoglobulin mucin domain-containing protein 3 (Tim-3) negatively regulates innate and adaptive immunity in cancer. To identify the mechanisms of Tim-3 in cancer immunity, we evaluated the effects of Tim-3 blockade in human and mouse melanom
Externí odkaz:
https://doaj.org/article/00341078d5a94f57ba93043742d00efb
Autor:
Matthew H. Taylor, Manish R. Patel, John D. Powderly, Paul Woodard, Luke Chung, Hongyu Tian, Xiang Hong, Kyu Hong, Donna Valencia, Tao Huang, Xiao Min Schebye, Charlene Liao, Aung Naing
Publikováno v:
Cancer Research. 83:CT040-CT040
Background: IO-108 is a fully human IgG4 monoclonal antibody with high affinity and specificity towards LILRB2 (also known as ILT4). It blocks the interaction of LILRB2 with the known ligands for LILRB2, including HLA-G, ANGPTLs, SEMA4A and CD1d. Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6599c2dec42591a331157c9eaa306a96
https://doi.org/10.1158/1538-7445.am2023-ct040
https://doi.org/10.1158/1538-7445.am2023-ct040
Autor:
Cheng-Chi Chao, Pengfei Zhou, Lawrence L'Italien, Xiao Min Schebye, Danling Gu, Junzhuan Qiu, Douglas Hodges
Publikováno v:
Journal of Immunotherapy. 33:789-797
An agonistic antibody DTA-1, to glucocorticoid-induced TNFR-related protein (GITR), induces T-cell activation and antitumor immunity. CD4(+) effector T cells are essential in initiating GITR-induced immune activation, and the sequentially activated c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bf0865ab09f1fa3666d5aac721daff
https://doi.org/10.1097/cji.0b013e3181ee6ba9
https://doi.org/10.1097/cji.0b013e3181ee6ba9
Publikováno v:
The Journal of Immunology. 179:7365-7375
Glucocorticoid-induced TNF receptor family related protein (GITR) is a member of the TNFR superfamily. Previous studies have shown that in vivo administration of a GITR agonistic Ab (DTA-1) is able to overcome tolerance and induce tumor rejection in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e2fd15ad20fc344149bef60d97d67b
https://doi.org/10.4049/jimmunol.179.11.7365
https://doi.org/10.4049/jimmunol.179.11.7365
Publikováno v:
Cell cycle (Georgetown, Tex.). 5(9)
A series of studies published in 2003 has challenged the essentiality of Cdk2. A recently published work indicates that cyclin E-Cdk1 compensates for Cdk2's function at G1/S transition in Cdk2(-/-) Mefs. In this study, we uncovered a redundant mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e50786c9176c3c05b17dcf760416bdf
https://pubmed.ncbi.nlm.nih.gov/16687918
https://pubmed.ncbi.nlm.nih.gov/16687918
Autor:
Doll Ronald J, Yonghong Zhu, Emma Lees, Xiao Min Schebye, David A.D. Parry, Carmen S. Alvarez, Hirokazu Kurata
To ensure proper progression through a cell cycle, checkpoints have evolved to play a surveillance role in maintaining genomic integrity. In this study, we demonstrate that loss of CDK2 activity activates an intra-S-phase checkpoint. CDK2 inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48da945cd5e8289f6395eddb4ec2536
https://europepmc.org/articles/PMC434231/
https://europepmc.org/articles/PMC434231/
Publikováno v:
Cell Cycle; May2006, Vol. 5 Issue 9, p984-993, 10p