Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Xiao Mei Qi"'
Autor:
Xiao-Mei Qi, Guan Chen
Publikováno v:
Cells, Vol 12, Iss 13, p 1674 (2023)
p38γ MAPK (also called ERK6 or SAPK3) is a family member of stress-activated MAPKs and has common and specific roles as compared to other p38 proteins in signal transduction. Recent studies showed that, in addition to inflammation, p38γ metabolic s
Externí odkaz:
https://doaj.org/article/f82237967aa148a784c6fb143fac468d
Akademický článek
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Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 1, p 031 (2022)
p38 MAPK (mitogen-activated protein kinases) family proteins (α, β, γ and δ) are key inflammatory kinases and play an important role in relaying and processing intrinsic and extrinsic signals in response to inflammation, stress, and oncogene to r
Externí odkaz:
https://doaj.org/article/f671e6e0ac834f859c713e9baf4a12ce
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 8, Iss 4, Pp 511-517 (2018)
Protein kinases and phosphatases signal by phosphorylation and dephosphorylation to precisely control the activities of their individual and common substrates for a coordinated cellular outcome. In many situations, a kinase/phosphatase complex signal
Externí odkaz:
https://doaj.org/article/218630de7dc745fa8a6f3a740286ae7a
Autor:
Guan Chen, Liwu Fu, Ramon Bartrons Bach, Charles R. Myers, Michael Dwinell, Alexander Mackinnon, James Thomas, Susan Tsai, Pengyuan Liu, Michael James, Yuri Sheinin, John Evans, Catherine Hagen, Matthew Mortensen, Ryan Wertz, Xiao-Mei Qi, Fang Wang
Figure S2. p38ÃŽÃ,³ knockout (KO) decreases p-Rb and CDK6 protein levels, slows G1/S transition, and inhibits cell growth, migration, and invasion in KPC cells, but lacks significant effects in PanIN lesions in KC mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70281160814f0734eb94b01381316a68
https://doi.org/10.1158/0008-5472.22423434.v1
https://doi.org/10.1158/0008-5472.22423434.v1
Autor:
Guan Chen, Liwu Fu, Ramon Bartrons Bach, Charles R. Myers, Michael Dwinell, Alexander Mackinnon, James Thomas, Susan Tsai, Pengyuan Liu, Michael James, Yuri Sheinin, John Evans, Catherine Hagen, Matthew Mortensen, Ryan Wertz, Xiao-Mei Qi, Fang Wang
KRAS is mutated in most pancreatic ductal adenocarcinomas (PDAC) and yet remains undruggable. Here, we report that p38γ MAPK, which promotes PDAC tumorigenesis by linking KRAS signaling and aerobic glycolysis (also called the Warburg effect), is a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a99aaaf7275f0a9afbbee242fbfd8b21
https://doi.org/10.1158/0008-5472.c.6511497.v1
https://doi.org/10.1158/0008-5472.c.6511497.v1
Autor:
Guan Chen, Zainab Basir, Rong-Shan Li, Xiao-Mei Qi, Mathew Loesch, Nicole Pohl, Hui-Ying Zhi, Song-Wang Hou
Supplementary Methods, Figures 1-4, Table 1 from PTPH1 Dephosphorylates and Cooperates with p38γ MAPK to Increase Ras Oncogenesis through PDZ-Mediated Interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abdf579d6e0e06d1c6cfaa35ff03231
https://doi.org/10.1158/0008-5472.22387149.v1
https://doi.org/10.1158/0008-5472.22387149.v1
Publikováno v:
Frontiers in Bioscience-Landmark. 27:1
Publikováno v:
Encyclopedia of Signaling Molecules ISBN: 9781461464389
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3050a5e4ca569a45f3422c29d2ecb2a
https://doi.org/10.1007/978-3-319-67199-4_101521
https://doi.org/10.1007/978-3-319-67199-4_101521
Publikováno v:
The Journal of China Universities of Posts and Telecommunications. 20:11-16
Business process families provide a unified representation of the possible business processes of a specific domain for rapid developments. The configuration of business process families depends on a group of stakeholders' requirements. However, multi