Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Xiao Jiang Yu"'
Autor:
Ming Zhao, Run-Qing Xue, Qing Wu, Dong-Ling Li, Wei-Jin Zang, Xi He, Xiao-Jiang Yu, Shengpeng Wang
Publikováno v:
Cell Cycle
Lipid droplets (LDs), which are neutral lipid storage organelles, are important for lipid metabolism and energy homeostasis. LD lipolysis and interactions with mitochondria are tightly coupled to cellular metabolism and may be potential targets to bu
Autor:
Yong-Hua Yang, Dong-Ling Li, Xue-Yuan Bi, Lei Sun, Xiao-Jiang Yu, Huan-Le Fang, Yi Miao, Ming Zhao, Xi He, Jin-Jun Liu, Wei-Jin Zang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 5, Pp 2025-2038 (2015)
Background: Excessive activation of matrix metalloproteinase 9 (MMP-9) has been found in several inflammatory diseases. Previous studies have shown that acetylcholine (ACh) reduced the levels of pro-inflammatory cytokines and decreased tissue damage.
Externí odkaz:
https://doaj.org/article/533e612514d24fb89de7d2197d15325d
Autor:
Ming Zhao, Xi He, Yong-Hua Yang, Xiao-Jiang Yu, Xue-Yuan Bi, Yang Yang, Man Xu, Xing-Zhu Lu, Qiang Sun, Wei-Jin Zang
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 4, Pp 481-488 (2015)
The Ca2+-sensing receptor (CaSR) plays an important role in regulating vascular tone. In the present study, we investigated the positive effects of the vagal neurotransmitter acetylcholine by suppressing CaSR activation in mesenteric arteries exposed
Externí odkaz:
https://doaj.org/article/ba902d49b6ad4b1582dee676ee0cd0ba
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 5, Pp 1614-1625 (2014)
Background/Aims: Acetylcholine (ACh) is known to modulate the cardiac redox environment and thereby suppress reactive oxygen species (ROS) generation during oxidative stress. However, there is little information about its regulation on ROS clearance.
Externí odkaz:
https://doaj.org/article/65b03d4d540442768d3a9a2b83a6824b
Autor:
Hong-Ke Jiang, You-Hua Wang, Lei Sun, Xi He, Mei Zhao, Zhi-Hui Feng, Xiao-Jiang Yu, Wei-Jin Zang
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 4, Pp 5304-5322 (2014)
Aerobic interval training (AIT) can favorably affect cardiovascular diseases. However, the effects of AIT on post-myocardial infarction (MI)—associated mitochondrial dysfunctions remain unclear. In this study, we investigated the protective effects
Externí odkaz:
https://doaj.org/article/c3d181c914484a948db51c0d0260ffaf
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 3, Pp 601-613 (2013)
Background: Acetylcholine (ACh), a neurotransmitter of vagal nerve, offers tolerance to ischemia/reperfusion injury. Given the regulation of autophagy in cardioprotection, this study was to examine the role of autophagy in ACh-elicited protection aga
Externí odkaz:
https://doaj.org/article/b88dd12ba9eb4fae9f3654a442a36af4
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 11, Pp 14311-14325 (2012)
Reactive oxygen species (ROS) production is an important mechanism in myocardial ischemia and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is one of major sources of ROS in the heart. Previous studies showed that vagus nerve stimulatio
Externí odkaz:
https://doaj.org/article/1c7e093198f84c9baabb6f65286d7ba4
Autor:
Lei Sun, Jun Lu, Xiao-Jiang Yu, Dong-Ling Li, Xiao-Li Xu, Bing Wang, Ke-Yu Ren, Jian-Kang Liu, Wei-Jin Zang
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 2, Pp 205-213 (2011)
Recent studies have shown that vagal activation may have an important therapeutic implication for myocardial infarction (MI), but effective strategies remain unexplored. Here, we investigate whether adenine sulfate can preserve cardiac function and t
Externí odkaz:
https://doaj.org/article/1750ae0198dd493a976c0249d3e40988
Autor:
Ming Zhao, Xiao-Jiang Yu, Wei-Jin Zang, Si Yang, Run-Qing Xue, Qing Wu, Dong-Ling Li, Yan-Ling Cui, Man Xu
Publikováno v:
Free Radical Biology and Medicine. 134:119-132
Insulin resistance and autonomic imbalance are important pathological processes in metabolic syndrome-induced cardiac remodeling. Recent studies determined that disruption of mitochondrial cristae shape is associated with myocardial ischemia; however
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 40(11)
Objective: Phenotypic switching of vascular smooth muscle cells (VSMCs) plays a critical role in atherosclerosis, vascular restenosis, and hypertension. Choline exerts cardioprotective effects; however, little is known about its effects on VSMC pheno