Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Xiao Jian Sun"'
Autor:
Xiaoquan Rao, Michael Razavi, Georgeta Mihai, Yingying Wei, Zachary Braunstein, Matthew B. Frieman, Xiao Jian Sun, Quan Gong, Jun Chen, Gang Zhao, Zheng Liu, Michael J. Quon, Lingli Dong, Sanjay Rajagopalan, Jixin Zhong
Publikováno v:
Advanced Science, Vol 10, Iss 9, Pp n/a-n/a (2023)
Abstract T cells play a crucial role in atherosclerosis, with its infiltration preceding the formation of atheroma. However, how T‐cell infiltration is regulated in atherosclerosis remains largely unknown. Here, this work demonstrates that dipeptid
Externí odkaz:
https://doaj.org/article/1a03d47b9fa342238ccecd0a4c5e5f9b
Autor:
Kai Xue, Ji-Chuan Wu, Xi-Ya Li, Ran Li, Qun-ling Zhang, Jin-Jia Chang, Yi-Zhen Liu, Chun-Hui Xu, Jia-Ying Zhang, Xiao-Jian Sun, Juan J. Gu, Wei-Jian Guo, Lan Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-11 (2021)
Abstract Rituximab/chemotherapy relapsed and refractory B cell lymphoma patients have a poor overall prognosis, and it is urgent to develop novel drugs for improving the therapy outcomes. Here, we examined the therapeutic effects of chidamide, a new
Externí odkaz:
https://doaj.org/article/01cbf1d04174447286c96ab3ad4ae816
Autor:
Fan Zhang, Qi-Yu Zeng, Hao Xu, Ai-Ning Xu, Dian-Jia Liu, Ning-Zhe Li, Yi Chen, Yi Jin, Chun-Hui Xu, Chang-Zhou Feng, Yuan-Liang Zhang, Dan Liu, Na Liu, Yin-Yin Xie, Shan-He Yu, Hao Yuan, Kai Xue, Jing-Yi Shi, Ting Xi Liu, Peng-Fei Xu, Wei-Li Zhao, Yi Zhou, Lan Wang, Qiu-Hua Huang, Zhu Chen, Sai-Juan Chen, Xiao-Long Zhou, Xiao-Jian Sun
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-17 (2021)
Abstract The amino acid response (AAR) and unfolded protein response (UPR) pathways converge on eIF2α phosphorylation, which is catalyzed by Gcn2 and Perk, respectively, under different stresses. This close interconnection makes it difficult to spec
Externí odkaz:
https://doaj.org/article/fd805927c9df437cbb23cd88b541200f
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 9, Pp 602-613 (2021)
Lymphoma is a common and aggressive form of hematopoietic malignancies with diverse clinical and pathological features due to its heterogeneity. Although the current immunochemotherapeutic regimens improve clinical outcomes, many patients still displ
Externí odkaz:
https://doaj.org/article/99ef0f3a554f4d2193e3654d4ed18325
Autor:
Yi-Fan Zhang, Xiao-Lin Wang, Chun-Hui Xu, Na Liu, Ling Zhang, Yu-Ming Zhang, Yin-Yin Xie, Yuan-Liang Zhang, Qiu-Hua Huang, Lan Wang, Zhu Chen, Sai-Juan Chen, Robert G. Roeder, Shuhong Shen, Kai Xue, Xiao-Jian Sun
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The ETO-family transcriptional corepressors, including ETO, ETO2, and MTGR1, are all involved in leukemia-causing chromosomal translocations. In every case, an ETO-family corepressor acquires a DNA-binding domain (DBD) to form a typical transcription
Externí odkaz:
https://doaj.org/article/8a602dc4f5f34b6aa8aa68c6b8b9d60a
Autor:
Ya-Kai Fu, Yun Tan, Bo Wu, Yu-Ting Dai, Xiao-Guang Xu, Meng-Meng Pan, Zhi-Wei Chen, Niu Qiao, Jing Wu, Lu Jiang, Jing Lu, Bing Chen, Avigail Rein, Shai Izraeli, Xiao-Jian Sun, Jin-Yan Huang, Qiu-Hua Huang, Zhu Chen, Sai-Juan Chen
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-17 (2021)
Abstract GATA2, a key transcription factor in hematopoiesis, is frequently mutated in hematopoietic malignancies. How the GATA2 mutants contribute to hematopoiesis and malignant transformation remains largely unexplored. Here, we report that Gata2-L3
Externí odkaz:
https://doaj.org/article/070f84f5a9a041eb8a6fce56b49ec3ee
Autor:
Ying Fang, Mu‐Chen Zhang, Peng‐Peng Xu, Su‐Jiang Zhang, Li Wang, Shu Cheng, Di Fu, Chun‐Kang Chang, Xiao‐Jian Sun, Yan Zhao, Yi‐Jia Tang, Xin Tian, Hong‐Mei Yi, Feng Liu, Wei‐Li Zhao
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/1346a5afdf334778bbbf99e4d1966114
Autor:
Yuting Dai, Aining Xu, Jianfeng Li, Liang Wu, Shanhe Yu, Jun Chen, Weili Zhao, Xiao-Jian Sun, Jinyan Huang
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-20 (2021)
Abstract Background The rapidly increasing dimensionality and throughput of flow and mass cytometry data necessitate new bioinformatics tools for analysis and interpretation, and the recently emerging single-cell-based algorithms provide a powerful s
Externí odkaz:
https://doaj.org/article/ff8ba4a7e2bf471bb17b266ef27514a7
Autor:
Yao-Hui Huang, Kun Cai, Peng-Peng Xu, Li Wang, Chuan-Xin Huang, Ying Fang, Shu Cheng, Xiao-Jian Sun, Feng Liu, Jin-Yan Huang, Meng-Meng Ji, Wei-Li Zhao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract Epigenetic alterations play an important role in tumor progression of diffuse large B-cell lymphoma (DLBCL). However, the biological relevance of epigenetic gene mutations on tumor microenvironment remains to be determined. The core set of g
Externí odkaz:
https://doaj.org/article/082abdeeebbb4e8a9f26361b0e286609
Autor:
Jie Xiong, Nan Wang, Hui-Juan Zhong, Bo-Wen Cui, Shu Cheng, Rui Sun, Jia-Yi Chen, Peng-Peng Xu, Gang Cai, Li Wang, Xiao-Jian Sun, Jin-Yan Huang, Wei-Li Zhao
Publikováno v:
EBioMedicine, Vol 72, Iss , Pp 103614- (2021)
Background: Metabolic reprogramming plays an essential role on lymphoma progression. Dysregulation of glutamine metabolism is implicated in natural-killer T-cell lymphoma (NKTCL) and tumor cell response to asparaginase-based anti-metabolic treatment.
Externí odkaz:
https://doaj.org/article/af0d5b4be7e9461b9c915d99a1f6ab28