Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Xiao Huo"'
Autor:
Jiaqi Huang, Qianqian Yin, Yuqing Wang, Xin Zhou, Yunyun Guo, Yuanjun Tang, Rui Cheng, Xiaotong Yu, Jie Zhang, Chen Huang, Zhanya Huang, Jianlin Zhang, Zhengyang Guo, Xiao Huo, Yan Sun, Yanfang Li, Hao Wang, Jianling Yang, Lixiang Xue
Publikováno v:
Advanced Science, Vol 11, Iss 23, Pp n/a-n/a (2024)
Abstract The regulation of PD‐L1 is the key question, which largely determines the outcome of the immune checkpoint inhibitors (ICIs) based therapy. However, besides the transcription level, the protein stability of PD‐L1 is closely correlated wi
Externí odkaz:
https://doaj.org/article/d6dbdb4db2dc4d5bb8cacfb58f1b695d
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Tumors with BRCA1/2 mutations or homologous recombination repair defects are sensitive to PARP inhibitors through the mechanism of synthetic lethality. Several PARP inhibitors are currently approved for ovarian, breast and pancreatic cancer in clinic
Externí odkaz:
https://doaj.org/article/154b1d42355942db821cf39571e87edb
Autor:
Tengrui Zhang, Zhengyang Guo, Xiao Huo, Yueqing Gong, Chen Li, Jiaqi Huang, Yan Wang, Hao Feng, Xiaojuan Ma, Changtao Jiang, Qianqian Yin, Lixiang Xue
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103872- (2022)
Summary: Background: Sensitivity has been a key issue for Enhancer of zeste homolog 2 (EZH2) inhibitors in cancer therapy. The EZH2 inhibitor EPZ-6438 was first approved by the US Food and Drug Administration (FDA) in 2020. However, its inadequate an
Externí odkaz:
https://doaj.org/article/0662ed4407564567ac1a57d87e32c475
Publikováno v:
IEEE Access, Vol 8, Pp 75884-75893 (2020)
Micro-lens array (MLA) based light field cameras have been commercialized and had a wide range of applications in various fields in recent years. To promote these applications, especially for 3D reconstruction, it is crucial to calibrate light field
Externí odkaz:
https://doaj.org/article/719a33c96b654e6cba8692449a4213eb
Publikováno v:
Applied Sciences, Vol 12, Iss 16, p 8179 (2022)
Point clouds are widely used as representations of 3D objects and scenes in a number of applications, including virtual and mixed reality, autonomous driving, antiques reconstruction. To reduce the cost for transmitting and storing such data, this pa
Externí odkaz:
https://doaj.org/article/f41b4040e19b4049b0b1732c749c4d71
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Background: Ovarian cancer is highly malignant and has a poor prognosis in the advanced stage. Studies have shown that infiltration of tumor microenvironment cells, immune cells and stromal cells has an important impact on the prognosis of cancers. H
Externí odkaz:
https://doaj.org/article/d7ba24a2d01a42f79a8842ee9207f540
Autor:
Xiao Huo, Hengzi Sun, Qiuhong Qian, Xiangwen Ma, Peng Peng, Mei Yu, Ying Zhang, Jiaxin Yang, Dongyan Cao, Ting Gui, Keng Shen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
BackgroundOvarian cancer has the highest mortality rate among gynecologic cancers, and most patients are diagnosed in advanced stages. Enhancer of zeste homolog 2 (EZH2) is a major tumor marker and an effective therapeutic target for ovarian cancer,
Externí odkaz:
https://doaj.org/article/5b23e49b02d24f618c7fb95db46d8034
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Purpose: To investigate the efficacy of fertility-sparing treatment for young women with grade 2 presumed stage IA endometrioid endometrial adenocarcinoma (EEA).Methods: We performed a retrospectively review of eight patients affected by grade 2 pres
Externí odkaz:
https://doaj.org/article/e31ee40b7d164be8bfcc9550663578a7
Clinical and Expression Significance of AKT1 by Co-expression Network Analysis in Endometrial Cancer
Autor:
Xiao Huo, Hengzi Sun, Qian Liu, Xiangwen Ma, Peng Peng, Mei Yu, Ying Zhang, Dongyan Cao, Keng Shen
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Introduction: Endometrial cancer is one of the most common uterine cancers worldwide. AKT is reported to regulate progesterone receptor B dependent transcription and angiogenesis in endometrial cancer. However, the potential mechanisms of AKT in the
Externí odkaz:
https://doaj.org/article/3a7bf657ad6342bab62e36eaafd88193
Autor:
Hengzi Sun, Dongyan Cao, Xiangwen Ma, Jiaxin Yang, Peng Peng, Mei Yu, Huimei Zhou, Ying Zhang, Lei Li, Xiao Huo, Keng Shen
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Introduction: Ovarian cancer is a highly malignant cancer with a poor prognosis. At present, there is no accurate strategy for predicting the prognosis of ovarian cancer. A prognosis prediction signature associated with DNA repair genes in ovarian ca
Externí odkaz:
https://doaj.org/article/086ec58daf724158bff294459a90cda0