Výsledky vyhledávání - "Xiao Bo Miao"

A novel miR-200c/c-myc negative regulatory feedback loop is essential to the EMT process, CSC biology and drug sensitivity in nasopharyngeal cancer

Autor: Jing Yang, Yue Wu, Qiuzhen Liu, Si-Pei Wu, Xiao-Bo Miao, Kaitai Yao, De-Ming Gou, Wen-Jun Wang, Zhi-Ru Jin

Publikováno v: Experimental Cell Research. 391:111817

Overexpression of the c-Myc oncogene has been implicated in cancer stem cell - like (CSC) phenotypes and epithelial-to-mesenchymal transition (EMT) in cancer. However, the underlying molecular mechanism by which c-Myc regulates EMT and CSC potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bbdea71b3fac42b742be1fc28b5c29
https://doi.org/10.1016/j.yexcr.2020.111817

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Cancer stem-like cell properties are regulated by EGFR/AKT/β-catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma

Autor: Ying Liu, Qiu Zhen Liu, Kai Tai Yao, Xi Qing Li, Lei Ma, Guang Hui Xiao, Gong Zhang, Yue Wu, Zhi Ru Jin, Xiao Bo Miao, Xu Bin Deng, Du Xin Sun, Joseph R. Testa

Publikováno v: FEBS Journal. 280:2027-2041

We report that the epidermal growth factor receptor (EGFR) pathway plays a critical role in regulating cancer stem-like cells (CSCs) in nasopharyngeal carcinoma (NPC), one of the most common malignant tumors in Southeast Asia. Effects of EGFR on main

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005c2538e446bac32fbdb9279d446a45
https://doi.org/10.1111/febs.12226

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Sulforaphane inhibits cancer stem-like cell properties and cisplatin resistance through miR-214-mediated downregulation of c-MYC in non-small cell lung cancer

Autor: Qiuzhen Liu, Qian-Qian Li, Linlin Li, Guang-Hui Xiao, Ying Liu, Yue Wu, You-Ke Xie, Xiao-Bo Miao, Kaitai Yao

Publikováno v: Oncotarget

// Qian-Qian Li 1, * , You-Ke Xie 1, * , Yue Wu 1 , Lin-Lin Li 1 , Ying Liu 1 , Xiao-Bo Miao 1 , Qiu-Zhen Liu 1 , Kai-Tai Yao 1 , Guang-Hui Xiao 1 1 Cancer Institute, Southern Medical University, Guangzhou 510515, China * These authors have contribut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099b784909a7467b7f5562d9f61d358f
https://pubmed.ncbi.nlm.nih.gov/28076844

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Esophageal cancer tumorspheres involve cancer stem-like populations with elevated aldehyde dehydrogenase enzymatic activity

Autor: Gong Zhang, Xiao-Bo Miao, Lei Ma, Chuan Jin, You-ke Xie

Publikováno v: Molecular Medicine Reports. 6:519-524

Cancer stem cells (CSCs) form spheres in vitro in serum-free suspension culture. Sphere formation is particularly useful to enrich the potential CSC subpopulations as a functional approach. Few reports are currently available on tumorspheres in esoph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2529b8ead799e874a677c523ac42c87
https://doi.org/10.3892/mmr.2012.939

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