Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Xiao‐jia Wang"'
Autor:
Jia-Ni Pan, Pu-Chun Li, Meng Wang, Ming-Wei Li, Xiao-Wen Ding, Tao Zhou, Hui-Na Wang, Yun-Kai Wang, Li-Bin Chen, Rong Wang, Wei-Wu Ye, Wei-Zhu Wu, Feng Lou, Xiao-Jia Wang, Wen-Ming Cao
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-10 (2024)
Abstract Purpose Our study aimed to develop and validate a homologous recombination deficiency (HRD) scoring algorithm in the Chinese breast cancer population. Methods and materials Ninety-six in-house breast cancer (BC) samples and 6 HRD-positive st
Externí odkaz:
https://doaj.org/article/61b76e98d4284ee985b5bf92ea9c589a
Publikováno v:
Clinical Case Reports, Vol 12, Iss 4, Pp n/a-n/a (2024)
Key Clinical Message In a patient with metastatic breast cancer, an acquired BRCA mutation in the BRCA gene was detected, resulting in benefits from olaparib treatment. This underscores the importance of ongoing genetic phenotype testing after paclit
Externí odkaz:
https://doaj.org/article/a454c43fc3c1406cb2820b8e92a0176a
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/9291bcf6d9c6495984e12eb53d3b6a45
Autor:
Rui-yuan Jiang, Zi-ru Fang, Huan-ping Zhang, Jun-yao Xu, Jia-yu Zhu, Ke-yu Chen, Wei Wang, Xiao Jiang, Xiao-jia Wang
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-28 (2023)
Abstract In 2021, breast cancer accounted for a substantial proportion of cancer cases and represented the second leading cause of cancer deaths among women worldwide. Although tumor cells originate from normal cells in the human body, they possess d
Externí odkaz:
https://doaj.org/article/b91188b18efb49939065c3cf4a93a4f5
Autor:
Ziyan Yang, Jianguo Feng, Ji Jing, Yuan Huang, Wei-Wu Ye, Lei Lei, Xiao-Jia Wang, Wen-Ming Cao
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract HER2-positive breast cancer patients carrying the germline TSC2 nonsynonymous variant c.4349 C > G (p.Pro1450Arg) are resistant to anti-HER2 therapy. Multi-predictor in silico analysis reveals that this variant is deleterious. We explore the
Externí odkaz:
https://doaj.org/article/dcd85a3b676d48349e729cc84beb2f2a
Autor:
Jin-Hu Fan, Su Zhang, Huan Yang, Zong-Bi Yi, Qu-Chang Ouyang, Min Yan, Xiao-Jia Wang, Xi-Chun Hu, Ze-Fei Jiang, Tao Huang, Zhong-Sheng Tong, Shu-Sen Wang, Yong-Mei Yin, Hui Li, Run-Xiang Yang, Hua-Wei Yang, Yue-E. Teng, Tao Sun, Li Cai, Hong-Yuan Li, Xue-Nong Ouyang, Jian-Jun He, Xin-Lan Liu, Shun-E. Yang, Jia-Yu Wang, Bing-He Xu, You-Lin Qiao
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
ObjectiveThis study aimed to explore possible associations between molecular subtypes and site of distant metastasis in advanced breast cancer (ABC).Methods3577 ABC patients were selected from 21 hospitals of seven geographic regions in China from 20
Externí odkaz:
https://doaj.org/article/d59fc4f00f5042a8a6ce6d73845e9301
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Carriers with BRCA1/2 germline pathogenic variants are associated with a high risk of breast and ovarian cancers (also pancreatic and prostate cancers). While the spectrum on germline BRCA mutations among the Chinese population shows ethnic specifici
Externí odkaz:
https://doaj.org/article/5e6450c42a9343da852d99fc25992a95
Autor:
Ping Huang, Jia-huan Huang, Ya-bing Zheng, Wen-ming Cao, Xi-ying Shao, Jun-qing Chen, Yuan Huang, Guang-liang Li, K Sharma, Huan-huan Zhou, Xiao-jia Wang, Hong-chuan Jin, Zhan-hong Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Cardiotoxicity associated with the sequential use of anthracyclines followed by trastuzumab is common in adjuvant therapy of patients with HER2-positive early breast cancer (eBC). However, the cardiac safety of trastuzumab concurrent with
Externí odkaz:
https://doaj.org/article/b9ada211e4b54f6bacce908dbd891efc
Autor:
Wen-Jun Tian, Xiao-Jia Wang
Publikováno v:
Viruses, Vol 15, Iss 5, p 1100 (2023)
Scientific advances have led to the development and production of numerous vaccines and antiviral drugs, but viruses, including re-emerging and emerging viruses, such as SARS-CoV-2, remain a major threat to human health. Many antiviral agents are rar
Externí odkaz:
https://doaj.org/article/c9cb827675594425a2850a7c788291ff
Autor:
Cui-Cui Li, Xiao-Jia Wang
Publikováno v:
Virology Journal, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background Porcine epidemic diarrhea virus (PEDV) of the family Coronaviridae has caused substantial economic losses in the swine husbandry industry. There’s currently no specific drug available for treatment of coronaviruses or PEDV. Meth
Externí odkaz:
https://doaj.org/article/ce877d3f2efc461581e84a023b067bb3