Zobrazeno 1 - 10
of 352
pro vyhledávání: '"Xiao‐Ming Yin"'
Autor:
Chenxiao Wang, Mst Shamima Khatun, Zhe Zhang, Michaela J. Allen, Zheng Chen, Calder R. Ellsworth, Joshua M. Currey, Guixiang Dai, Di Tian, Konrad Bach, Xiao-Ming Yin, Vicki Traina-Dorge, Jay Rappaport, Nicholas J. Maness, Robert V. Blair, Jay K. Kolls, Derek A. Pociask, Xuebin Qin
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract SARS-CoV-2 infection can cause persistent respiratory sequelae. However, the underlying mechanisms remain unclear. Here we report that sub-lethally infected K18-human ACE2 mice show patchy pneumonia associated with histiocytic inflammation a
Externí odkaz:
https://doaj.org/article/15de162092a24f62b3a66615cbf80085
Autor:
Bilon Khambu, Genxiang Cai, Gang Liu, Niani Tiaye Bailey, Arissa A. Mercer, Kamal Baral, Michelle Ma, Xiaoyun Chen, Yu Li, Xiao-Ming Yin
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Injury or stress can induce intracellular translocation and release of nuclear HMGB1, a DAMP molecule known to participate in inflammation and other pathological processes. Active release of HMGB1 from stimulated macrophages can be mediated
Externí odkaz:
https://doaj.org/article/ca573ba96c04491fa66ef547cc44b55f
Autor:
Taylor J Abele, Zachary P Billman, Lupeng Li, Carissa K Harvest, Alexia K Bryan, Gabrielle R Magalski, Joseph P Lopez, Heather N Larson, Xiao-Ming Yin, Edward A Miao
Publikováno v:
eLife, Vol 12 (2023)
Pyroptosis and apoptosis are two forms of regulated cell death that can defend against intracellular infection. When a cell fails to complete pyroptosis, backup pathways will initiate apoptosis. Here, we investigated the utility of apoptosis compared
Externí odkaz:
https://doaj.org/article/7eb48fcbd0d1487191217dd2ceb4740a
Autor:
Katherine Byrnes, Niani Tiaye Bailey, Kamal Baral, Arissa Mercer, Spandan Joshi, Nickol Wahby, Tyler Rorison, Gang Liu, Xiao-Ming Yin, Bilon Khambu
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Hepatotoxins activate the hepatic survival pathway, but it is unclear whether impaired survival pathways contribute to liver injury caused by hepatotoxins. We investigated the role of hepatic autophagy, a cellular survival pathway, in choles
Externí odkaz:
https://doaj.org/article/156cd16952f14d86b125c1f0583b67f5
Autor:
Shengmin Yan, Jun Zhou, Hao Zhang, Zhen Lin, Bilon Khambu, Gang Liu, Michelle Ma, Xiaoyun Chen, Naga Chalasani, Xiao‐Ming Yin
Publikováno v:
Hepatology Communications, Vol 6, Iss 12, Pp 3349-3362 (2022)
Abstract A growing body of evidence has indicated an expanding functional network of B‐cell lymphoma 2 (BCL‐2) family proteins beyond regulation of cell death and survival. Here, we examined the role and mechanisms of BH3 interacting‐domain dea
Externí odkaz:
https://doaj.org/article/0e5360b219444b849366cce026cd33b9
Autor:
Jiahui Long, Xia Luo, Dongmei Fang, Haikun Song, Weibin Fang, Hao Shan, Peiqing Liu, Boxun Lu, Xiao-Ming Yin, Liang Hong, Min Li
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Huntington’s disease (HD) is a neurodegenerative disorder caused by aggregation of the mutant huntingtin (mHTT) protein encoded from extra tracts of CAG repeats in exon 1 of the HTT gene. mHTT proteins are neurotoxic to render the death of
Externí odkaz:
https://doaj.org/article/8f89bb3958d34310afa77354245e8cca
Autor:
Sarah Reagan-Steiner, Julu Bhatnagar, Roosecelis B. Martines, Nicholas S. Milligan, Carly Gisondo, Frank B. Williams, Elizabeth Lee, Lindsey Estetter, Hannah Bullock, Cynthia S. Goldsmith, Pamela Fair, Julie Hand, Gillian Richardson, Kate R. Woodworth, Titilope Oduyebo, Romeo R. Galang, Rebecca Phillips, Elizaveta Belyaeva, Xiao-Ming Yin, Dana Meaney-Delman, Timothy M. Uyeki, Drucilla J. Roberts, Sherif R. Zaki
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 3, Pp 510-517 (2022)
Severe coronavirus disease in neonates is rare. We analyzed clinical, laboratory, and autopsy findings from a neonate in the United States who was delivered at 25 weeks of gestation and died 4 days after birth; the mother had asymptomatic severe acut
Externí odkaz:
https://doaj.org/article/dbba9e5d326d4e7fb088350a577698de
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286726 (2023)
Increased uptake of fat, such as through the ingestion of high fat diet (HFD), can lead to fatty liver diseases and metabolic syndrome. It is not clear whether certain fatty acids may be more pathogenic than others to the liver. Linoleic acid (LA) is
Externí odkaz:
https://doaj.org/article/be447e0c24bc4ae082f06c6b8cdaf96c
Autor:
Shengmin Yan, Xiao-Ming Yin
Publikováno v:
Liver Research, Vol 5, Iss 3, Pp 151-163 (2021)
An increasing amount of evidence has shown critical roles of gut microbiome in host pathophysiology. The gut and the liver are anatomically and physiologically connected. Given the critical role of gut-liver axis in the homeostasis of the liver, gut
Externí odkaz:
https://doaj.org/article/970c1a2618ab4f4e9166b9d6ecb174a6
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 973-997 (2021)
Background & Aims: The functions of the liver and the intestine are closely tied in both physiological and pathologic conditions. The gut microbiota (GM) often cause deleterious effects during hepatic pathogenesis. Autophagy is essential for liver ho
Externí odkaz:
https://doaj.org/article/9952d7d39a7b42c587e6ef23bbe51ec2