Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Xiao‐Kui Wang"'
Publikováno v:
Molecules, Vol 20, Iss 12, Pp 22272-22285 (2015)
Bedaquiline is the first FDA-approved new chemical entity to fight multidrug-resistant tuberculosis in the last forty years. Our group replaced the quinoline ring with a naphthalene ring, leading to a new type of triarylbutanol skeleton. An asymmetri
Externí odkaz:
https://doaj.org/article/97c8a9a5f64e4698af2e386ef685a8ff
Autor:
Guo-Ming Zhao, Zhi-Bing Zheng, Dong-Mei Zhao, Xiao-Kui Wang, Guang-Qiang Xia, Xiu-Yan Yang, Song Li
Publikováno v:
Molecules, Vol 18, Iss 9, Pp 11144-11152 (2013)
An efficient synthesis of enantiopure (R)-heteroarylpyrimidine analogs is described here, which involves introduction of a chiral group, formation and separation of diasteroisomers and final transformation of an amide to an ester. The absolute config
Externí odkaz:
https://doaj.org/article/8a33f4e2d43e4ad7aa5696328068f126
Autor:
Jun‐Nian Zhou, Biao Zhang, Hai‐Yang Wang, Dong‐Xing Wang, Ming‐Ming Zhang, Min Zhang, Xiao‐Kui Wang, Shi‐Yong Fan, Ying‐Chen Xu, Quan Zeng, Ya‐Li Jia, Jia‐Fei Xi, Xue Nan, Li‐Juan He, Xin‐Bo Zhou, Song Li, Wu Zhong, Wen Yue, Xue‐Tao Pei
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(22)
Cancer stem cells (CSCs) are reported to play essential roles in chemoresistance and metastasis. Pathways regulating CSC self-renewal and proliferation, such as Hedgehog, Notch, Wnt/β-catenin, TGF-β, and Myc, may be potential therapeutic targets. H
Publikováno v:
Bioorganic chemistry. 102
Bedaquiline (TMC207), a typical diarylquinoline anti-tuberculosis drug, has been approved by FDA to specifically treat MDR-TB. Herein we describe design, synthesis, and in vitro biological evaluation against Mycobacterium tuberculosis of a series of
Publikováno v:
Instrumentation Science & Technology. 34:743-753
An electrokinetic flow analysis system was introduced for reversed‐phase chromatography separation. It consisted of a C8‐modified silica monolithic column, a UV‐Vis detector, and a pressurizing electroosmosis pump (EOP) to deliver mobile phase
Autor:
Jing, Song, Hui-Ling, Guo, Da-Jiang, Wang, Ji-Feng, Yu, Gai-Ping, DU, Xiao-Kui, Wang, Yi-Fei, Huang
Publikováno v:
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology. 47(5)
To study the cell membrane of corneal endothelium with a micromolecular compound J2 in corneal allograft of rat using atomic force microscopy (AFM).Cohort study. Subjects were divided into two groups: group A (n = 15): experimental group; group B (n
Publikováno v:
Guang pu xue yu guang pu fen xi = Guang pu. 30(3)
In the present paper, a laboratory-made high-performance electrophoresis microcolumn unit was prepared for UV-Vis spectrophotometer. X-ray diffraction was used in the preparation of electrophoretic microcolumns. And an analytical technique of microco
Publikováno v:
Talanta. 79(2)
The feasibility of a microcolumn electrophoresis technique was investigated with a 100 mm length, 2 mm I.D. fused-silica microcolumn packed with uniform quartz microncrystals prepared by hydrothermal synthesis. To evaluate the separation technique, t
Publikováno v:
Talanta. 74(1)
A simple and convenient method of micellar electrokinetic capillary chromatography (MEKC) using polyoxyethylene sorbitan monolaurate (Tween 20) to form single micelle and methanol as a buffer additive was introduced for the simultaneous determination
Publikováno v:
Talanta. 70(2)
A porous core electroosmosis pump was studied and improved in accordance with the electroosmosis theory. Hexamethylene tetraamine (HMTA) was used as the additive of pump carrier solution to improve the flow rate stability and delivery efficiency. The