Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Xiao‐Kang Lu"'
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107800- (2023)
Summary: Reproductive strategy is among the most important characteristics of organism. Here, we report reproductive strategy of singleton pregnancy of a fossil rhinoceros, Plesiaceratherium gracile, from 18 mya of the Shanwang Basin, China. Dental a
Externí odkaz:
https://doaj.org/article/d5125c52567c4bc2bfaecdaa6ce2e1eb
Publikováno v:
Frontiers in Ecology and Evolution, Vol 11 (2023)
This study presents the first phylogenetic analysis focused on the subfamily Aceratheriinae to date, with 392 characters (361 parsimony-informative characters) coded from 50 taxa at the species level. We added 80 newly defined and 33 revised characte
Externí odkaz:
https://doaj.org/article/1fdd3c5636644efeb1b666a5df678da0
Publikováno v:
The Anatomical Record.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84fbaa6f735580e539c7e1b79a382117
https://doi.org/10.1002/ar.25186
https://doi.org/10.1002/ar.25186
Publikováno v:
Open Chemistry, Vol 16, Iss 1, Pp 407-414 (2018)
The present study explores the mechanism of resistance to pulmonary fibrosis by observing the possible effects of serum containing drugs prepared from Gua Lou Xie Bai decoction (GLXB-D) on transforming growth factor beta 1 (TGF-β1) induced Epithelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205ad9667ec90edf59868ee55fbb2c26
https://doaj.org/article/0f26392d8185428c87739b1a6c07deb8
https://doaj.org/article/0f26392d8185428c87739b1a6c07deb8
Autor:
Ron Sarver, Christopher Whitehead, Heidi Baum, James Hicks, Richard Gowan, Brian Sanchez, Xiao Kang Lu, Susan E. Bove, Joseph A. Cornicelli, Howard Miller, Sandra Lightle, Aurash B Shahripour, Katherine Welch, Craig Banotai, Jayvardhan Pandit, Mark S. Plummer, Timothy Braden, David Beidler, Adam Ogden, Skalitzky Donald James, Annise Paige Goodman, Howard Roark, Nalini Sadagopan, Charles J. Stankovic, Cindy Spessard, Xi Qiang Shen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:3438-3442
We identified potent, selective PDE2 inhibitors by optimizing residual PDE2 activity in a series of PDE4 inhibitors, while simultaneously minimizing PDE4 activity. These newly designed PDE2 inhibitors bind to the PDE2 enzyme in a cGMP-like mode in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128c0eb423facb1ebd01be1c3f41f3b1
https://doi.org/10.1016/j.bmcl.2013.03.072
https://doi.org/10.1016/j.bmcl.2013.03.072
Autor:
Skalitzky Donald James, Craig Banotai, Jayvardhan Pandit, Adam Ogden, James Hicks, Annise Paige Goodman, Xiao Kang Lu, Howard Miller, Howard Roark, Susan E. Bove, Sandra Lightle, Aurash B Shahripour, Timothy Braden, Mark S. Plummer, Katherine Welch, Charles J. Stankovic, Ron Sarver, Joseph A. Cornicelli, Christopher Whitehead, Brian Sanchez, Nalini Sadagopan, Heidi Baum, Richard Gowan, David Beidler, Xi Qiang Shen, Cindy Spessard
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:3443-3447
Selective phosphodiesterase 2 (PDE2) inhibitors are shown to have efficacy in a rat model of osteoarthritis (OA) pain. We identified potent, selective PDE2 inhibitors by optimizing residual PDE2 activity in a series of phosphodiesterase 4 (PDE4) inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a8df19422ac729711863e191ea116e
https://doi.org/10.1016/j.bmcl.2013.03.082
https://doi.org/10.1016/j.bmcl.2013.03.082
Autor:
Wen-qin HUANG, Kai CUI, Yong HAN, Jian-min CHAI, Shi-qin WANG, Xiao-kang LÜ, Qi-yu DIAO, Nai-feng ZHANG
Publikováno v:
Journal of Integrative Agriculture, Vol 21, Iss 4, Pp 1146-1160 (2022)
Early life intervention is important to shape the gut microbiome profiles of adult animals due to the tremendous alteration of diet components. Nevertheless, there is still no unified understanding about its long-term effects in lambs. In this study,
Externí odkaz:
https://doaj.org/article/dedf752c373d4d339c246a8dd6add425
Autor:
Vito RT Zanotelli, Matthias Leutenegger, Xiao‐Kang Lun, Fanny Georgi, Natalie de Souza, Bernd Bodenmiller
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp 1-21 (2020)
Abstract Cells react to their microenvironment by integrating external stimuli into phenotypic decisions via an intracellular signaling network. To analyze the interplay of environment, local neighborhood, and internal cell state effects on phenotypi
Externí odkaz:
https://doaj.org/article/577f6dc37c6a41c6a2fe8bda0a9e1fce
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Intracellular signaling pathways are at the core of cellular information processing. The states of these pathways and their inputs determine signaling dynamics and drive cell function. Within a cancerous tumor, many combinations of cell states and mi
Externí odkaz:
https://doaj.org/article/98a27bfdd17a4bf28adcc91a9d898a72
Autor:
Maria Anna Rapsomaniki, Xiao-Kang Lun, Stefan Woerner, Marco Laumanns, Bernd Bodenmiller, María Rodríguez Martínez
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Mass cytometry is a powerful method of single cell analysis, but potential confounding effects of cell cycle and cell volume are not taken into account. Here the authors present a combined experimental and computational method to correct for these ef
Externí odkaz:
https://doaj.org/article/88cf8b87f8f24c58a5be08d7dbf1d961