Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Xiao‐Jiang Quan"'
Autor:
Carmen Bravo González‐Blas, Xiao‐Jiang Quan, Ramon Duran‐Romaña, Ibrahim Ihsan Taskiran, Duygu Koldere, Kristofer Davie, Valerie Christiaens, Samira Makhzami, Gert Hulselmans, Maxime de Waegeneer, David Mauduit, Suresh Poovathingal, Sara Aibar, Stein Aerts
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 5, Pp 1-32 (2020)
Abstract Single‐cell technologies allow measuring chromatin accessibility and gene expression in each cell, but jointly utilizing both layers to map bona fide gene regulatory networks and enhancers remains challenging. Here, we generate independent
Externí odkaz:
https://doaj.org/article/32070ef12bcb4df19d0631375f7ed3e5
Publikováno v:
Endocrine and Metabolic Science, Vol 5, Iss , Pp 100106- (2021)
A stable narrow range of extracellular calcium concentration in the blood is essential for life. The calcium-sensing receptor (CaSR), a member of the G protein-coupled receptors family, is required to adjust the set point of blood extracellular calci
Externí odkaz:
https://doaj.org/article/2a8c6c43a3e04a188ff7b5eaa76f2dcc
Autor:
Stein Aerts, Xiao-Jiang Quan, Annelies Claeys, Marina Naval Sanchez, Phillip Tate, Jiekun Yan, Bassem A Hassan
Publikováno v:
PLoS Biology, Vol 8, Iss 7, p e1000435 (2010)
A comprehensive systems-level understanding of developmental programs requires the mapping of the underlying gene regulatory networks. While significant progress has been made in mapping a few such networks, almost all gene regulatory networks underl
Externí odkaz:
https://doaj.org/article/cd19c781272241a2850d6f85798250d6
Autor:
Stein Aerts, Sven Vilain, Shu Hu, Leon-Charles Tranchevent, Roland Barriot, Jiekun Yan, Yves Moreau, Bassem A Hassan, Xiao-Jiang Quan
Publikováno v:
PLoS Genetics, Vol 5, Iss 1, p e1000351 (2009)
Genetic screens are powerful methods for the discovery of gene-phenotype associations. However, a systems biology approach to genetics must leverage the massive amount of "omics" data to enhance the power and speed of functional gene discovery in viv
Externí odkaz:
https://doaj.org/article/48b8e25fcd7f4b29aabd731c461451d8
Publikováno v:
Oncology Letters
Establishing the link between cellular processes and oncogenesis may aid the elucidation of targeted and effective therapies against tumor cell proliferation and metastasis. Previous studies have investigated the mechanisms involved in maintaining th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e548c7e6bad014a17f0ed0f39b2a021
http://europepmc.org/articles/PMC7400680
http://europepmc.org/articles/PMC7400680
Autor:
Jasper Janssens, Sara Aibar, Ibrahim Ihsan Taskiran, Joy N. Ismail, Alicia Estacio Gomez, Gabriel Aughey, Katina I. Spanier, Florian V. De Rop, Carmen Bravo González-Blas, Marc Dionne, Krista Grimes, Xiao Jiang Quan, Dafni Papasokrati, Gert Hulselmans, Samira Makhzami, Maxime De Waegeneer, Valerie Christiaens, Tony Southall, Stein Aerts
The Drosophila brain is a frequently used model in neuroscience. Single-cell transcriptome analysis1-6, three-dimensional morphological classification7 and electron microscopy mapping of the connectome8,9 have revealed an immense diversity of neurona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87607de00f68769629154bd50c4b66a7
https://lirias.kuleuven.be/handle/20.500.12942/688974
https://lirias.kuleuven.be/handle/20.500.12942/688974
Autor:
Katina I. Spanier, J. N. Ismail, Gert Hulselmans, Stein Aerts, Xiao-Jiang Quan, C. Bravo Gonzalez-Blas, Samira Makhzami, Ibrahim Ihsan Taskiran, Sara Aibar, Valerie Christiaens, M. De Waegeneer, Janssens J, Dafni Papasokrati
SummaryTheDrosophilabrain is a work horse in neuroscience. Single-cell transcriptome analysis1–5,3D morphological classification6, and detailed EM mapping of the connectome7–10have revealed an immense diversity of neuronal and glial cell types th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07788b3facad7ad4ddad86f9eded842e
https://doi.org/10.1101/2021.08.11.454937
https://doi.org/10.1101/2021.08.11.454937
Publikováno v:
Current Gene Therapy
Background: Myocardial infarction (MI) is the most severe ischemic heart disease and directly leads to heart failure till death. Target molecules have been identified in the event of MI including increasing angiogenesis, promoting cardiomyocyte survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea73615106cfae21d7db95ca8cbaa16a
https://doi.org/10.2174/1566523218666181003125308
https://doi.org/10.2174/1566523218666181003125308
Publikováno v:
Endocrine and Metabolic Science, Vol 5, Iss, Pp 100106-(2021)
A stable narrow range of extracellular calcium concentration in the blood is essential for life. The calcium-sensing receptor (CaSR), a member of the G protein-coupled receptors family, is required to adjust the set point of blood extracellular calci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6406a1eab799776272b32b5a071ca26
https://doi.org/10.1016/j.endmts.2021.100106
https://doi.org/10.1016/j.endmts.2021.100106
Publikováno v:
Current stem cell researchtherapy. 16(5)
Macrophage proliferation and skewed myelopoiesis-induced monocytosis, as well as neutrophils, enhance the generation of atherogenic inflammatory cells in a lesion area, leading to plaque formation and Cardiovascular Disease (CVD). Among all risk fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb928f0cb3a8469e992ed2b6d7f1ad48
https://pubmed.ncbi.nlm.nih.gov/32000654
https://pubmed.ncbi.nlm.nih.gov/32000654