Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Xianyi Sha"'
Autor:
Yiting Chen, Xinhong Li, Kuankuan Luo, Tao Wang, Tongyao Liu, Enhao Lu, Rui Wang, Yu Luo, Xianyi Sha
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101085- (2024)
Breast cancer is the most diagnosed malignancy in women globally, and drug resistance is among the major obstacles to effective breast cancer treatment. Emerging evidence indicates that photothermal therapy and ferroptosis are both promising therapeu
Externí odkaz:
https://doaj.org/article/bcbf09ff5914478595ed7b567b545611
Autor:
Rui Wang, Tongyao Liu, Xinhong Li, Enhao Lu, Yiting Chen, Kuankuan Luo, Tao Wang, Xueli Huang, Zhiwen Zhang, Shilin Du, Xianyi Sha
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 3, Pp 100913- (2024)
Flare and multiple recurrences pose significant challenges in gouty arthritis. Traditional treatments provide temporary relief from inflammation but fail to promptly alleviate patient pain or effectively prevent subsequent recurrences. It should also
Externí odkaz:
https://doaj.org/article/de097ec3b1244bcc9f2306bbfa00c978
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Ferroptosis plays a critical role in ischemic stroke, and anti-ferroptosis strategies were regarded as potentially effective measures. Based on ferroptosis-related mechanisms, this study aims to design and prepare anti-ferroptosis exosomes f
Externí odkaz:
https://doaj.org/article/bd2c54daa487426d9039ca63b41777a0
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 25 (2023)
Developing drugs that are highly selective to host tissues but are the least toxic remains one of the most difficult challenges in cancer treatment. Recent studies have shown that tumor cells from a variety of sources can express vitamin D3 receptors
Externí odkaz:
https://doaj.org/article/461f19cdf631430db1133253a74acff7
Autor:
Xin Yan, Xianyi Sha
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2457 (2023)
Airway mucus is a complex viscoelastic gel composed mainly of water, glycoproteins, lipids, enzymes, minerals, etc. Among them, glycoproteins are the main factors determining mucus’s gel-like rheology. Airway mucus forms a protective barrier by sec
Externí odkaz:
https://doaj.org/article/fb94bfc8debc41dfabd7aa0bb63aec2a
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 799 (2021)
This study aimed to investigate the idarubicin loading method, compatible stability with contrast agent, release profiles, and morphological properties of 50–150, 100–300, and 300–500 μm CalliSpheres®. The amounts of idarubicin added, loading
Externí odkaz:
https://doaj.org/article/096ec14f967f47618fa69276d5df65a7
Publikováno v:
Pharmaceutics, Vol 12, Iss 8, p 776 (2020)
(1) Background: It is common practice in the treatment of respiratory diseases to mix different inhalation solutions for simultaneous inhalation. At present, a small number of studies have been published that evaluate the physicochemical compatibilit
Externí odkaz:
https://doaj.org/article/949fba86670e400eb0fb6e98c575512e
Autor:
Zhuoyang Fan, Cheng Chen, Xiaoying Pang, Zhou Yu, Yang Qi, Xinyi Chen, Huihui Liang, Xiaoling Fang, Xianyi Sha
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120129 (2015)
Genexol-PM, produced by Samyang Company (Korea) is an excellent preparation of paclitaxel (PTX) for clinical cancer treatment. However, it cannot resolve the issue of multidrug resistance (MDR)-a significant problem in the administration of PTX to ca
Externí odkaz:
https://doaj.org/article/8ee811f198b84f74ab3d5ab709c9e2e6
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80390 (2013)
Previous research suggests that carbohydrate mimetic peptide IF7 (IFLLWQR) has an excellent targeting property to annexin1 (Anxa1), a specific marker on the tumor endothelium. However, IF7 is susceptible to proteolysis and has a poor stability in viv
Externí odkaz:
https://doaj.org/article/770582914a4b4b20ad719316eed7c249
Supplementary Table 1. PBPK model-predicted veliparib plasma pharmacokinetic (PK) parameters and mechanistic kidney model parameters under different scenarios. Supplementary Figure S1. In vitro metabolism of veliparib. The disappearance of veliparib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21aaff2257c7f7d2ea0a3f756dbedec8
https://doi.org/10.1158/1078-0432.22460772
https://doi.org/10.1158/1078-0432.22460772