Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Xianwen Gan"'
Publikováno v:
Tetrahedron. 71:3325-3332
A facile and efficient method for the synthesis of 3,4-disubstituted-furan-2(5 H )-one derivatives using PdCl 2 (dppf) 2 as catalyst via the Suzuki–Miyaura reaction was reported. 3,4-Dibenzylfuran-2(5 H )-ones were synthesized through the coupling
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:435-437
The natural product arctigenin (ATG) demonstrated preferential cytotoxicity to cancer cells under glucose starvation. A series of 4-amino-4-dehydroxylarctigenin derivatives based on lead compound ATG were designed and synthesized by bioisosteric modi
Autor:
Xin-gang Yao, Min Lei, Fanglei Chen, Chengqian Xiao, Xianwen Gan, Yunan Tian, Lihong Hu, Jing Chen, Xu Shen
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(5)
It is demonstrated that natural product vindoline can enhance the glucose-stimulated insulin secretion (GSIS) in MIN6 cells with the EC50 value of 50.2μM. In order to improve the activities, a series of vindoline derivatives are synthesized and eval
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 143:825-830
A facile method of synthesizing 8-oxoprotoberberines is described from 6-benzoyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline-5-carbaldehyde via acid-mediated cyclization or from 2-(2-iodophenethyl)isoquinolin-1(2H)-one via the Heck reaction. T
Publikováno v:
Planta Medica. 75:1344-1348
Six new terpenoids, including three diterpenoids ( 1- 3), one norditerpenoid ( 4) and two sesquiterpenoids ( 11 and 12), were isolated from the roots of CHLORANTHUS HENRYI. The structures were elucidated mainly by 1D, and 2D NMR and MS experiments, a
Publikováno v:
Organic Letters. 11:589-592
Two sequential Suzuki coupling reactions have been developed for efficient synthesis of synthetically and biologically important 3,6-disubstituted 2,5-dioxybenzoquinone architectures in a highly chemoselective controlled manner. The method serves as
Publikováno v:
Natural Product Research. 22:623-627
Three new chalcone C-glycosides named schoepfin A, B, C (1-3), together with three known compounds 4,2',4'-trihydroxy-3'-C-beta-D-glucosylchalcone (4), nothofagin (5) and hemiphloin (6) were isolated from ethanolic extract of the bark of Schoepfia ch
Publikováno v:
ChemInform. 46
The Suzuki—Miyaura reaction of dibromide (I) with excess benzyltrifluoroborates (II) in the presence of Cs2CO3 leads to 3,4-symmetric dibenzyl-furanones (III), whilst the reaction with a stoichiometric amount of benzyltrifluoroborates (II) in the p
Publikováno v:
ChemInform. 43
Publikováno v:
ChemInform. 41
Jatrophalactam (1), a novel diterpenoid lactam possessing an unprecedented 5/13/3 tricyclic skeleton, was isolated from the roots of Jatropha curcas. The structure and relative configuration of jatrophalactam (1) were elucidated by extensive spectros