Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Xianwen Chen"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
ObjectiveAmong the disturbing motor symptoms in Parkinson’s disease (PD), freezing of gait (FOG) stands out as one of the most severe challenges. It typically arises during the initiation of gait or when turning. This phenomenon not only impose a h
Externí odkaz:
https://doaj.org/article/2af3d82113544e509ed1cd04f5c8b07d
Publikováno v:
Brain Research Bulletin, Vol 213, Iss , Pp 110991- (2024)
Neurodegenerative diseases such as Parkinson's disease (PD) have complex pathogenetic mechanisms. Genetic, age, and environmental factors are all related to PD. Due to the unclear pathogenesis of PD and the lack of effective cure methods, it is urgen
Externí odkaz:
https://doaj.org/article/bcc6c270bbaa44a982fff786ba932552
Publikováno v:
International Journal of Health Policy and Management, Vol 12, Iss Issue 1, Pp 1-15 (2023)
Background Benchmarking has been increasingly used on drug regulatory systems to achieve sustainable pharmaceutical system strengthening. This study aimed to identify the scope, tools and benefits of benchmarking regulatory capacities and the most re
Externí odkaz:
https://doaj.org/article/51872f969d1d4263ba4d57b1e135cbdc
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-40 (2023)
Abstract Background Cancer-related fatigue (CRF) is an extremely common and long-term condition that affects the physical and mental health of oncology patients. While the treatment for CRF with western medicine and non-pharmacological therapy remain
Externí odkaz:
https://doaj.org/article/92e65b1411fd4022a18544d747b8d858
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionAlthough restriction of vertical ocular range of motion is known to be the hallmark of progressive supranuclear palsy (PSP), the maximal amplitude of ocular movement has not been quantitatively assessed despite of accumulating evidences o
Externí odkaz:
https://doaj.org/article/8f8171e709854b6c88a3a0df0cc43879
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background Non-alcoholic steatohepatitis (NASH) is a liver disease currently lacking an approved therapy, resulting in significant clinical demand. Traditional Chinese medicines (TCMs) have been commonly used to manage NASH. This study aimed
Externí odkaz:
https://doaj.org/article/efdf0027035d4691a931073da5cb409d
Autor:
Yan Xue, Huimin Zou, Zhen Ruan, Xianwen Chen, Yunfeng Lai, Dongning Yao, Carolina Oi Lam Ung, Hao Hu
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionPharmacological therapy is recommended as a second-line alternative to reverse obesity. Currently, five anti-obesity drugs (AODs) have been approved by the U.S. Food and Drug Administration (FDA) for chronic weight management. The aim of
Externí odkaz:
https://doaj.org/article/acd6f7620743429ab8411509a4268263
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Chronic fatigue syndrome (CFS) is an increasingly common condition that is challenging to treat due to unclear etiology and a lack of consensus on clinical diagnosis and treatment guidance. Many affected people resorted to using traditi
Externí odkaz:
https://doaj.org/article/6b816dea2254465b9d47bb595211b86f
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionThe purpose of developing and adopting regulatory science (RS) for drug regulatory authorities (DRAs) is to enhance regulatory capacity by advancing the scientific approach for the evaluation of health-related products. While many DRAs ar
Externí odkaz:
https://doaj.org/article/b3ca8372a8a249039f2ae4393fa2989c
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundThe downregulation of monoamines, especially dopamine in substantia nigra (SN) and norepinephrine in locus coeruleus (LC), may be responsible for freezing of gait (FOG) pathological basis in Parkinson’s disease (PD).MethodsThirty-two Park
Externí odkaz:
https://doaj.org/article/785a365b3cd94ce18289b1a801ead0d8