Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Xianwa Niu"'
Autor:
Oyekoya T. Ayonrinde, Katherine A. Stuart, Trevor A. Mori, Malcolm Webb, Michael J. House, Kevin D. Croft, Gary P. Jeffrey, Timothy G. St. Pierre, John K. Olynyk, H. Ching, Xianwa Niu, Jenny Kava, Leon A. Adams, Darrell H. G. Crawford, Gerry MacQuillan, Michael Bynevelt, George Garas
Publikováno v:
Hepatology. 61:1555-1564
Iron is implicated in the pathogenesis of liver injury and insulin resistance (IR) and thus phlebotomy has been proposed as a treatment for nonalcoholic fatty liver disease (NAFLD). We performed a prospective 6-month randomized, controlled trial exam
Publikováno v:
Liver Transplantation. 20:904-911
This study investigated iron-induced injury after warm ischemia in a non–heart-beating (NHB) rat liver model and the effects of deferoxamine (DFO). Livers from heart-beating (HB) rats or rats that were NHB for 60 minutes were stored in University o
Publikováno v:
Transplantation Proceedings. 42:1563-1568
Iron chelators and antioxidants have been shown to prevent hypothermia-induced apoptosis in hepatocytes. This study examined whether iron chelation and antioxidants could also prevent hypothermia-induced necrosis. Isolated rat hepatocytes were incuba
Publikováno v:
Free Radical Biology and Medicine. 44:24-33
Oxidative stress during cold preservation has been identified as a significant cause of cell injury but the process by which injury occurs is poorly understood. We examined loss of lysosomal integrity as a possible cause of cell injury during extende
Autor:
Xianwa Niu, Suzanne English, David J. Speers, Gary P. Jeffrey, William Reed, Gerry MacQuillan, Jane E. Allan, George Garas, Gerry B Harnett
Publikováno v:
Journal of Gastroenterology and Hepatology. 19:551-557
Background and Aim: The presence of four or more amino acid substitutions within the interferon sensitivity determining region (ISDR) of the hepatitis C virus (HCV) genotype 1b NS5A gene determines sensitivity to interferon (IFN) monotherapy in Japan
Autor:
Hongjie Wang, Anthony J. Kettle, Revathy Senthilmohan, Roland Stocker, Joanne M. Upston, Roger T. Dean, Ryuichi Mashima, Andrew J. Brown, Xianwa Niu
Publikováno v:
The American Journal of Pathology. 160:701-710
Oxidative modification of low-density lipoprotein is thought to promote arterial lipid accumulation and atherogenesis. Previous studies reported on the presence of certain lipid or protein oxidation products in lesions, although a systematic investig
Autor:
Xianwa, Niu, Wen Hua, Huang, Bastiaan, De Boer, Luc, Delriviere, Ling Jun, Mou, Gary P, Jeffrey
Publikováno v:
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 20(8)
This study investigated iron-induced injury after warm ischemia in a non-heart-beating (NHB) rat liver model and the effects of deferoxamine (DFO). Livers from heart-beating (HB) rats or rats that were NHB for 60 minutes were stored in University of
Publikováno v:
Journal of Cellular Physiology. 170:1-7
Isolated cell systems are now being used very effectively to study a range of important biochemical questions, but their energy metabolism has never been comprehensively investigated. We have developed a system, using J2E cells, which enables us to m
Autor:
Wen Hua Huang, Bastiaan DeBoer, Peter G. Arthur, Ching Tat Lai, Gary P. Jeffrey, Xianwa Niu, Enrico Rossi, John Joseph
To evaluate whether desferrioxamine decreases ischemia and perfusion injury aggravated by cold storage (CS) in a rat liver perfusion model.Isolated rat livers were kept in CS in University of Wisconsin Solution for 20 h at 4 °C, then exposed to 25 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd4bca3c36f817183be3c45a00ab99a
https://europepmc.org/articles/PMC3574593/
https://europepmc.org/articles/PMC3574593/
Publikováno v:
Comparative Haematology International. 2:35-43
During red cell storage the pH of the medium and that of the intracellular fluid decreases. The decrease in pH is due to glycolysis and is a likely contributor to red cell storage lesion. The trisodium salt of 3-phosphoglycerate (PGA) would be an ide