Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Xiansi Zeng"'
Thioredoxin-1 decreases alpha-synuclein induced by MPTP through promoting autophagy-lysosome pathway
Autor:
Rou Gu, Liping Bai, Fang Yan, Se Zhang, Xianwen Zhang, Ruhua Deng, Xiansi Zeng, Bo Sun, Xiaomei Hu, Ye Li, Jie Bai
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Parkinson’s disease (PD) is characterized by the formation of Lewy body in dopaminergic neurons in the substantia nigra pars compacta (SNpc). Alpha-synuclein (α-syn) is a major component of Lewy body. Autophagy eliminates damaged organell
Externí odkaz:
https://doaj.org/article/7daed040e59b492a9c65c2d12c48406d
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 11, Pp 2400-2410 (2024)
The inflammasome is a multiprotein complex involved in innate immunity that mediates the inflammatory response leading to pyroptosis, which is a lytic, inflammatory form of cell death. There is accumulating evidence that nucleotide-binding domain and
Externí odkaz:
https://doaj.org/article/75d9748ce7bb4ebf96dc0601d0277414
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/0d1e16ad13d849c8ac0cbccecfbfe5a0
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Since the first 70 years of reporting cancer chemotherapy, malignant tumors have been the second most common cause of death in children and adults. Currently, the commonly used anti-cancer methods include surgery, chemotherapy, radiotherapy, and immu
Externí odkaz:
https://doaj.org/article/070b4bece56442629771d1e203bafd28
Autor:
Jinjing Jia, Jiayi Yin, Yu Zhang, Guangtao Xu, Min Wang, Haiying Jiang, Li Li, Xiansi Zeng, Dongsheng Zhu
Publikováno v:
ASN Neuro, Vol 15 (2023)
Alzheimer's disease (AD) is the most common neurodegenerative disease. Increasing studies suggest that mitochondrial dysfunction is closely related to the pathogenesis of AD. Thioredoxin-1 (Trx-1), one of the major redox proteins in mammalian cells,
Externí odkaz:
https://doaj.org/article/c1ddade94a5849968cd78871bd1c3b32
Autor:
Liang Gong, Jiayi Yin, Yu Zhang, Ren Huang, Yuxuan Lou, Haojie Jiang, Liyan Sun, Jinjing Jia, Xiansi Zeng
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Panax ginseng and Panax notoginseng, two well-known herbs with enormous medical value in Asian countries, have a long usage history in China for the therapy of some diseases, such as stroke. Ginsenoside Rb1 is one of most important active ingredients
Externí odkaz:
https://doaj.org/article/5ad43e3d062a49c687d4583537dfb8b0
Autor:
Devin M. Barry, Xue-Ting Liu, Benlong Liu, Xian-Yu Liu, Fang Gao, Xiansi Zeng, Juan Liu, Qianyi Yang, Steven Wilhelm, Jun Yin, Ailin Tao, Zhou-Feng Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The role of gastrin related peptide (GRP+) neurons in itch is debated. Here, the authors generate a conditional knock-in mouse to label and manipulate GRP expressing DRG neurons and investigate their role in itch and nociception.
Externí odkaz:
https://doaj.org/article/53f793802fe24f6f9367fe8f40d917ea
Publikováno v:
ASN Neuro, Vol 13 (2021)
Alzheimer’s disease (AD) is the most common neurodegenerative diseases. Increasing studies have demonstrated the critical importance for redox proteins mediating neuronal protection in models of AD. This review briefly describes some of the risk fa
Externí odkaz:
https://doaj.org/article/a570539b11d44f5581b454d823f4402c
Publikováno v:
Molecular Biology Reports. 49:3445-3452
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1430dc22cf50adceefa0fda09fe0dfb
https://doi.org/10.1007/s11033-022-07177-8
https://doi.org/10.1007/s11033-022-07177-8
Publikováno v:
Current Stem Cell Research & Therapy. 16:958-969
Parkinson’s disease (PD) is a common neurodegenerative disease and is a major culprit that harms the health of elderly people. The main pathological feature is the progressive loss of dopaminergic neurons in the substantia nigra pars compacta of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c690c1572c8e34daa0a1d2fbd16eb1c8
https://doi.org/10.2174/1574888x16666210309153949
https://doi.org/10.2174/1574888x16666210309153949