Zobrazeno 1 - 10
of 555
pro vyhledávání: '"Xianqun, Fan"'
Publikováno v:
Holistic Integrative Oncology, Vol 3, Iss 1, Pp 1-13 (2024)
Abstract Retinoblastoma is the most common intraocular malignant tumor that poses a serious threat to the lives of children. Treatment plans for RB vary depending on the stage of the disease, and there is an uneven distribution of medical resources a
Externí odkaz:
https://doaj.org/article/874dadfc4bfa47d78a77acadc15787ec
Publikováno v:
European Thyroid Journal, Vol 13, Iss 4, Pp 1-10 (2024)
Background: Thyroid eye disease (TED) is an autoimmune orbital disease, with intravenous glucocorticoid (IVGC) therapy as the first-line treatment. Due to uncertain response rates and possible side effects, various prediction models have been develop
Externí odkaz:
https://doaj.org/article/5d3ea591b8e44f5bb8ae5e38e14f438d
Autor:
Hanhan Shi, Hao Tian, Tianyu Zhu, Qili Liao, Chang Liu, Peng Yuan, Yongyun Li, Jie Yang, Chunyan Zong, Shichong Jia, Jing Ruan, Shengfang Ge, Renbing Jia, Peiwei Chai, Shiqiong Xu, Xianqun Fan
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Conjunctival melanoma (CoM) is a potentially devastating tumor that can lead to distant metastasis. Despite various therapeutic strategies for distant metastatic CoM, the clinical outcomes remain unfavorable. Herein, we performed single-cell
Externí odkaz:
https://doaj.org/article/308ff374b615437b9c05b694d34ef349
Publikováno v:
BMJ Global Health, Vol 9, Iss 9 (2024)
Introduction This study examines the impact of China’s family doctor system (FDS) on healthcare utilisation and costs among diabetic patients with distinct long-term service utilisation patterns.Methods Conducted in City A, eastern China, this retr
Externí odkaz:
https://doaj.org/article/32f4252cd76b4f73934e583502530cc8
Autor:
Liang Ma, Jie Yu, Yidian Fu, Xiaoyu He, Shengfang Ge, Renbing Jia, Ai Zhuang, Zhi Yang, Xianqun Fan
Publikováno v:
MedComm, Vol 5, Iss 9, Pp n/a-n/a (2024)
Abstract Cellular senescence, one of the hallmarks of cancer, is characterized by cell cycle arrest and the loss of most normal cellular functions while acquiring a hypersecretory, proinflammatory phenotype. The function of senescent cells in cancer
Externí odkaz:
https://doaj.org/article/5eee344a33a245aa9270e4d2012a1c15
Autor:
Yongyun Li, Tianyu Zhu, Jie Yang, Qianqian Zhang, Shiqiong Xu, Shengfang Ge, Renbing Jia, Jianming Zhang, Xianqun Fan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1187-1203 (2024)
Constitutive activation of GNAQ/11 is the initiative oncogenic event in uveal melanoma (UM). Direct targeting GNAQ/11 has yet to be proven feasible as they are vital for a plethora of cellular functions. In search of genetic vulnerability for UM, we
Externí odkaz:
https://doaj.org/article/3eb653eb05ac41c1a5eceecc08536f44
Autor:
Haiyang Zhang, Yuting Liu, Duojin Xia, Mengda Jiang, Yinwei Li, Jing Sun, Haixia Guan, Ling Zhu, Xuefei Song, Jue Wang, Xianqun Fan, Huifang Zhou
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background Thyroid eye disease (TED) is highly correlated with dysregulated immunoendocrine status. The insular cortex was found to regulate peripheral inflammation and immunomodulation in mice. This study aimed to explore whether the insula
Externí odkaz:
https://doaj.org/article/11a4f13973bf4052878ed104face73a1
Autor:
Haiyang Zhang, Mengda Jiang, Hoi Chi Chan, Huijie Zhang, Jiashuo Xu, Yuting Liu, Ling Zhu, Xiaofeng Tao, Duojin Xia, Lei Zhou, Yinwei Li, Jing Sun, Xuefei Song, Huifang Zhou, Xianqun Fan
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Radiomics analysis of orbital magnetic resonance imaging (MRI) shows preliminary potential for intravenous glucocorticoid (IVGC) response prediction of thyroid eye disease (TED). The current region of interest segmentation contain
Externí odkaz:
https://doaj.org/article/b0d0e3db93e64d5988f71bb8983b53ec
Autor:
Ai Zhuang, Xiang Gu, Tongxin Ge, Shaoyun Wang, Shengfang Ge, Peiwei Chai, Renbing Jia, Xianqun Fan
Publikováno v:
Cancer Communications, Vol 43, Iss 11, Pp 1185-1206 (2023)
Abstract Background Diversified histone deacetylation inhibitors (HDACis) have demonstrated encouraging outcomes in multiple malignancies. N6‐methyladenine (m6A) is the most prevalent messenger RNA modification that plays an essential role in the r
Externí odkaz:
https://doaj.org/article/4ac9993639d944488fddab79b4e4859c
Autor:
Yijia Wu, Yao Lin, Feiyang Shen, Rui Huang, Zhe Zhang, Min Zhou, Yan Fang, Jianfeng Shen, Xianqun Fan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 49, Iss , Pp 100973- (2024)
F-box only protein 38 (FBXO38) is a member of the F-box family that mediates the ubiquitination and proteasome degradation of programmed death 1 (PD-1), and thus has important effects on T cell-related immunity. While its powerful role in adaptive im
Externí odkaz:
https://doaj.org/article/bff1cad3dd5345a1ae6bb09d7013864b