Výsledky vyhledávání - "Xianqi, Kong"

Solid-State 17O NMR Study of Carboxylic Acid Dimers: Simultaneously Accessing Spectral Properties of Low- and High-Energy Tautomers

Autor: Victor V. Terskikh, Ivan Hung, Zhehong Gan, Xianqi Kong, Gang Wu

Publikováno v: The Journal of Physical Chemistry A. 123:8243-8253

We report a solid-state 17O NMR study of several crystalline carboxylic acids. We found that, while each of these compounds forms discrete hydrogen-bonded dimers in the crystal lattice, their solid-state 17O magic-angle spinning (MAS) NMR spectra dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89dde587608ee97cf0c8aa82e6f41b57
https://doi.org/10.1021/acs.jpca.9b07224

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Differential inhibition of rat and mouse microsome heme oxygenase by derivatives of imidazole and benzimidazole

Autor: Maaike Hum, Jason Z. Vlahakis, Brian E. McLaughlin, Walter A. Szarek, Kanji Nakatsu, Dragic Vukomanovic, Xianqi Kong

Publikováno v: Canadian Journal of Physiology and Pharmacology. 95:1454-1461

Metalloporphyrin heme oxygenase (HO) inhibitors have made an important contribution to elucidating the role of HO in physiological processes. Nevertheless, their off-target effects have drawn substantial criticism, which prompted us to develop non-po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59678bc6a877554837628dea4a07a2d9
https://doi.org/10.1139/cjpp-2017-0236

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Solid-state 17O NMR study of 2-acylbenzoic acids and warfarin

Autor: Xianqi Kong, Gang Wu, Yizhe Dai

Publikováno v: Solid State Nuclear Magnetic Resonance. 84:59-64

We report synthesis and solid-state 17 O NMR characterization of four site-specifically 17 O-labeled 2-acylbenzoic acids (2-RC(O)C 6 H 4 COOH) where R=H and CH 3 ): 2-[3- 17 O]formylbenzoic acid, 2-[1,2- 17 O 2 ]formylbenzoic acid, 2-[3- 17 O]acetylb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3351887fe37a93bd99aea15817ae5573
https://doi.org/10.1016/j.ssnmr.2016.12.011

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Solid‐State 17 O NMR Reveals Hydrogen‐Bonding Energetics: Not All Low‐Barrier Hydrogen Bonds Are Strong

Autor: Jia-Sheng Lu, Andreas Brinkmann, Xianqi Kong, Ivan Hung, Zhehong Gan, Gang Wu

Publikováno v: Angewandte Chemie International Edition. 56:6166-6170

While NMR and IR spectroscopic signatures and structural characteristics of low‐barrier hydrogen bond (LBHB) formation are well documented in the literature, direct measurement of the LBHB energy is difficult. Here, we show that solid‐state 17O N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e3f9ad6d3c23a981ce34d1a3060469
https://doi.org/10.1002/anie.201700488

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Solid-State

Autor: Gang, Wu, Ivan, Hung, Zhehong, Gan, Victor, Terskikh, Xianqi, Kong

Publikováno v: The journal of physical chemistry. A. 123(38)

We report a solid-state

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5fa05ce7c425a17ee4ff72867b690c47
https://pubmed.ncbi.nlm.nih.gov/31454240

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Solid-State 17O NMR of Unstable Acyl-Enzyme Intermediates: A Direct Probe of Hydrogen Bonding Interactions in the Oxyanion Hole of Serine Proteases

Autor: Aaron W. Tang, Victor V. Terskikh, Gang Wu, Xianqi Kong

Publikováno v: The Journal of Physical Chemistry B. 120:11142-11150

We report preparation, trapping, and solid-state 17O NMR characterization of three unstable acyl-enzyme intermediates (≈ 26 kDa): p-N,N-dimethylamino-[17O]benzoyl-chymotrypsin, trans-o-methoxy-[17O]cinnamoyl-chymotrypsin, and trans-p-methoxy-[17O]c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d91d5a661350052bcc18df21bb81309b
https://doi.org/10.1021/acs.jpcb.6b08798

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Akademický článek

A solid-state ¹⁷O NMR study of platinum-carboxylate complexes: carboplatin and oxaliplatin.

Autor: Xianqi Kong¹, Terskikh, Victor^1,2, Toubaei, Abouzar¹, Gang Wu¹ gang.wu@chem.queensu.ca

Publikováno v: Canadian Journal of Chemistry. Sep2015, Vol. 93 Issue 9, p945-953. 9p. 3 Diagrams, 2 Charts, 4 Graphs.

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Inhibition of bacterial growth and galactosyltransferase activity of WbwC by α, ω-bis(3-alkyl-1H-imidazolium)alkane salts: Effect of varying carbon content

Autor: Jason Z. Vlahakis, Jacob Melamed, Alexander Kocev, Inka Brockhausen, Yaozu Xu, Shuo Wang, Xianqi Kong, Walter A. Szarek

Publikováno v: Bioorganic & Medicinal Chemistry. 28:115494

A series of compounds was designed and synthesized having two imidazolium rings separated by a polymethylene spacer and having alkyl substituents on each of the imidazolium rings. The compounds were assayed for their effects on the activity of galact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59cf343da4ea60a1699ad12977b7caff
https://doi.org/10.1016/j.bmc.2020.115494

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Solving the 170-Year-Old Mystery About Red-Violet and Blue Transient Intermediates in the Gmelin Reaction

Autor: Xianqi Kong, Abouzar Toubaei, Gang Wu, Yin Gao

Publikováno v: Chemistry - A European Journal. 21:17172-17177

The Gmelin reaction between nitroprusside and sulfides in aqueous solution is known to produce two transient intermediates with distinct colors: an initial red-violet intermediate that subsequently converts into a blue intermediate. In this work, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f447b9f4534dccaf64ea4d969687cdd
https://doi.org/10.1002/chem.201503353

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