Výsledky vyhledávání - "Xianpeng Jiang"

Akademický článek

Mitochondrial Toxicity of Azithromycin Results in Aerobic Glycolysis and DNA Damage of Human Mammary Epithelia and Fibroblasts

Autor: Xianpeng Jiang, Catherine Baucom, Robert L. Elliott

Publikováno v: Antibiotics, Vol 8, Iss 3, p 110 (2019)

Mitochondria evolved from free-living bacteria via endocytosis within eukaryotic host cells millions of year ago. We hypothesized that antibiotics cause mammalian mitochondrial damage while causing bacterial lethality. Mitochondrial toxicity of azith

Externí odkaz: https://doaj.org/article/ef38a8e3ff9b47ffad24b2efe83b0aaf

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Mitochondrial Organelle Transplantation Is a Potential Therapeutic for Mitochondria Dysfunction in Severe Acute Respiratory Syndrome (SARS) Coronavirus Diseases

Autor: Xianpeng Jiang, Catherine C. Baucom

Publikováno v: Advances in Infectious Diseases. 11:298-309

COVID-19 severe symptoms and high mortality are mainly seen in elders with age-associated diseases who have mitochondrial dysfunction. Mitochondrial dysfunction is a vulnerability and comorbidity of COVID-19. Cytokine storm, and increased serum iron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ccd7ee8466f60e4b8913137e2c416164
https://doi.org/10.4236/aid.2021.113027

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Mitochondria Dynamically Transplant into Cells in Vitro and in Mice and Rescue Aerobic Respiration of Mitochondrial DNA-Depleted Motor Neuron NSC-34

Autor: Robert L. Elliott, Catherine C. Baucom, Xianpeng Jiang

Publikováno v: Journal of Biomedical Science and Engineering. 13:203-221

It has been reported that transplantation of pheochromocytoma P12 and hepatoma cells’ mitochondria improve the locomotive activity and prevent disease progress in experimental Parkinson’s disease rats. To prepare for mitochondrial transplantation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1a45216cc5697d532068ae6adf8ea33
https://doi.org/10.4236/jbise.2020.139019

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Initial Experience with Contrast Enhanced Digital Mammography (SenoBright)—In a Comprehensive Clinical Breast Center

Autor: Xianpeng Jiang, Mary C. Elliott, Robert L. Elliott, Catherine C. Baucom, Emorly H. Millet

Publikováno v: Journal of Cancer Therapy. :146-154

Objective: The purpose of initiating contrast enhanced digital mammography in our center was to evaluate the complimentary benefit of this technology with screening digital mammography and real time ultrasound in equivocal cases and high risk patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb78d68cb513025c15bc954a036d4df2
https://doi.org/10.4236/jct.2017.82012

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Mitochondrial Toxicity of Azithromycin Results in Aerobic Glycolysis and DNA Damage of Human Mammary Epithelia and Fibroblasts

Autor: Robert L. Elliott, Catherine C. Baucom, Xianpeng Jiang

Publikováno v: Antibiotics, Vol 8, Iss 3, p 110 (2019)
Antibiotics
Volume 8
Issue 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53a88f3556a328078f1c7a6715f351d
https://www.mdpi.com/2079-6382/8/3/110

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Abstract 3795: Antibiotics induce mitochondrial dysfunction, DNA damage and aerobic glycolysis of human mammary epithelia and fibroblast

Autor: Xianpeng Jiang, Robert L. Elliott

Publikováno v: Cancer Research. 79:3795-3795

Mitochondria evolved from free-living bacteria after being endocytosed by eukaryotic host cells millions of year ago. We hypothesized that antibiotics could cause mammalian mitochondrial damage while causing bacterial lethality. Mitochondrial toxicit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e70a89e200d326ded48e2a98fb0e26c
https://doi.org/10.1158/1538-7445.am2019-3795

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Abstract 3600: Antibiotics suppress growth of breast cancer cells and synergize cytotoxicity of 2-Deoxy-D-glucose: Treating cancer like an infection

Autor: Robert L. Elliott, Toby Jiang, Amanda Benoit, Xianpeng Jiang

Publikováno v: Cancer Research. 79:3600-3600

Mitochondria evolved from free-living bacteria via endocytosis within a eukaryotic host cell millions of year ago. We hypothesized that antibiotics might damage mitochondria of human cancer cells and lead to oxidative damage of cancer cells. We exami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03a0d5f5c0e22c7d6ff403c8a0ae6c20
https://doi.org/10.1158/1538-7445.am2019-3600

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Exogenous normal mammary epithelial mitochondria suppress glycolytic metabolism and glucose uptake of human breast cancer cells

Autor: Robert L. Elliott, Jonathan F. Head, Xianpeng Jiang

Publikováno v: Breast Cancer Research and Treatment. 153:519-529

We hypothesized that normal mitochondria inhibited cancer cell proliferation and increased drug sensitivity by the mechanism of suppression of cancer aerobic glycolysis. To demonstrate the mechanism, we used real-time PCR and glycolysis cell-based as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33f889b7504bbc5edd20d2c8a6a9bd2
https://doi.org/10.1007/s10549-015-3583-0

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Decreased Iron in Cancer Cells and Their Microenvironment Improves Cytolysis of Breast Cancer Cells by Natural Killer Cells

Autor: Robert L. Elliott, Xianpeng Jiang

Publikováno v: Anticancer research. 37(5)

The association of iron with anticancer immunity is unclear. In order to determine the role of iron in anticancer immunity, we manipulated intracellular iron levels of the human MCF-7 and MDA-MB-231 breast cancer cell lines, and measured cytolysis of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7787d433f5d6dfdd73bcc0e1eedec8b7
https://pubmed.ncbi.nlm.nih.gov/28476795

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