Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Xianmei Qi"'
Autor:
Yanjiang Xing, Yangfeng Hou, Tianfei Fan, Ran Gao, Xiaohang Feng, Bolun Li, Junling Pang, Wenjun Guo, Ting Shu, Jinqiu Li, Jie Yang, Qilong Mao, Ya Luo, Xianmei Qi, Peiran Yang, Chaoyang Liang, Hongmei Zhao, Wenhui Chen, Jing Wang, Chen Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1726-1741 (2024)
Pulmonary hypertension (PH) is a fatal disorder characterized by pulmonary vascular remodeling and obstruction. The phosphodiesterase 4 (PDE4) family hydrolyzes cyclic AMP (cAMP) and is comprised of four subtypes (PDE4A–D). Previous studies have sh
Externí odkaz:
https://doaj.org/article/82a1a91c028b46718e666010f9ed51d1
Autor:
Meiyue Song, Jiaxin Wang, Youliang Sun, Junling Pang, Xiaona Li, Yuan Liu, Yitian Zhou, Peiran Yang, Tianhui Fan, Ying Liu, Zhaoguo Li, Xianmei Qi, Baicun Li, Xinri Zhang, Jing Wang, Chen Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 3, Pp 1213-1224 (2022)
Silicosis is a leading cause of occupational disease-related morbidity and mortality worldwide, but the molecular basis underlying its development remains unclear. An accumulating body of evidence supports gasdermin D (GSDMD)-mediated pyroptosis as a
Externí odkaz:
https://doaj.org/article/55aaf8605ea148b29c657cb5658a431d
Autor:
Junling Pang, Ya Luo, Dong Wei, Zhujie Cao, Xianmei Qi, Meiyue Song, Ying Liu, Zhaoguo Li, Jin Zhang, Baicun Li, Jingyu Chen, Jing Wang, Chen Wang
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Silicosis is a fatal occupational lung disease which currently has no effective clinical cure. Recent studies examining the underlying mechanism of silicosis have primarily examined experimental models, which may not perfectly reflect the nature of h
Externí odkaz:
https://doaj.org/article/cb997e45ccd34e779989e2dcb6b6f44e
Autor:
Ya Luo, Xianmei Qi, Zhenxi Zhang, Jiawei Zhang, Bolun Li, Ting Shu, Xiaona Li, Huiyuan Hu, Jinqiu Li, Qihao Tang, Yitian Zhou, Mingyao Wang, Tianfei Fan, Wenjun Guo, Ying Liu, Jin Zhang, Junling Pang, Peiran Yang, Ran Gao, Wenhui Chen
Publikováno v:
Circulation; 4/23/2024, Vol. 149 Issue 17, p1354-1371, 18p
Autor:
You-Liang Sun, Zhaoguo Li, Baicun Li, Meiyue Song, Yuan Liu, Pei-Ran Yang, Tian-Hui Fan, Xianmei Qi, Junling Pang, Jia-Xin Wang, Xin-Ri Zhang, Yitian Zhou, Xiaona Li, Jing Wang, Ying Liu, Chen Wang
Publikováno v:
Acta Pharmaceutica Sinica B. 12:1213-1224
Silicosis is a leading cause of occupational disease-related morbidity and mortality worldwide, but the molecular basis underlying its development remains unclear. An accumulating body of evidence supports gasdermin D (GSDMD)-mediated pyroptosis as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a90709f12cf04c52c6ef28e0d0739b
https://doi.org/10.1016/j.apsb.2021.10.006
https://doi.org/10.1016/j.apsb.2021.10.006
Autor:
Baicun Li, Jing Wang, Jingyu Chen, Chen Wang, Xianmei Qi, Dong Wei, Xiaona Li, Ting Shu, Ying Liu, Junling Pang, Ya Luo, Mei-Yue Song
Publikováno v:
Theranostics
Rationale: Silicosis is a severe occupational lung disease. Current treatments for silicosis have highly limited availability (i.e., lung transplantation) or, do not effectively prolong patient survival time (i.e., lung lavage). There is thus an urge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6163899f5fd854eaa9c22ecbcddb0b
http://europepmc.org/articles/PMC7797695
http://europepmc.org/articles/PMC7797695
Autor:
Zhujie Cao, Xin-Ri Zhang, Zhaoguo Li, Zhe Zhang, Xianmei Qi, Chen Wang, Pei-Ran Yang, Ying Liu, Jing Wang, Zhi-Fa Han, Meiyue Song, Junling Pang, Baicun Li, Hua-Ping Dai
Publikováno v:
Acta Pharmacol Sin
Silicosis is a global occupational disease characterized by lung dysfunction, pulmonary inflammation, and fibrosis, for which there is a lack of effective drugs. Pirfenidone has been shown to exert anti-inflammatory and anti-fibrotic properties in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d6f4c22eda6f8d608613a92f437c9f
https://europepmc.org/articles/PMC8976043/
https://europepmc.org/articles/PMC8976043/
Autor:
Jingyu Chen, Baicun Li, Zhujie Cao, Jing Wang, Jin Zhang, Zhaoguo Li, Dong Wei, Chen Wang, Xianmei Qi, Ying Liu, Meiyue Song, Ya Luo, Junling Pang
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
Frontiers in Genetics
Silicosis is a fatal occupational lung disease which currently has no effective clinical cure. Recent studies examining the underlying mechanism of silicosis have primarily examined experimental models, which may not perfectly reflect the nature of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49a92c0de6e98f8e0040e1095d94532
https://www.frontiersin.org/articles/10.3389/fgene.2021.652901/full
https://www.frontiersin.org/articles/10.3389/fgene.2021.652901/full
Autor:
Tian-Hui Fan, Yitian Zhou, Ya Luo, Jia-Xin Wang, Zhi-Fa Han, Xianmei Qi, Ying Liu, Pei-Ran Yang, You-Liang Sun, Baicun Li, Jing Wang, Xin-Ri Zhang, Chen Wang, Zhaoguo Li, Mei-Yue Song
Publikováno v:
Acta pharmacologica Sinica. 43(5)
Silicosis caused by inhalation of silica particles leads to more than ten thousand new occupational exposure-related deaths yearly. Exacerbating this issue, there are currently few drugs reported to effectively treat silicosis. Tetrandrine is the onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3549348083fbd089c092c73077ae0d2
https://pubmed.ncbi.nlm.nih.gov/34417574
https://pubmed.ncbi.nlm.nih.gov/34417574
Autor:
Dong Wei, Mei-Yue Song, Bolun Li, Jingyu Chen, Ting Shu, Chen Wang, Zhaoguo Li, Ying Liu, Junling Pang, Zhujie Cao, Jing Wang, Baicun Li, Xianmei Qi
Publikováno v:
Ecotoxicology and environmental safety. 202
Silicosis is caused by massive inhalation of silica-based particles, which leads to pulmonary inflammation, pulmonary fibrosis and lung dysfunction. Currently, the pathophysiological process of silicosis has not been well studied. Here, we defined th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1bc2c04715891a69539943ca73c8d5
https://pubmed.ncbi.nlm.nih.gov/32622305
https://pubmed.ncbi.nlm.nih.gov/32622305