Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Xianling, Gong"'
Autor:
Xianling Gong, Ruibo Sun, Zhuowei Gao, Weili Han, Yawei Liu, Liang Zhao, Linlin Jing, Xueqing Yao, Xuegang Sun
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/4bcb489c37304d0a8ec646d3b7911259
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 595-603 (2019)
With high morbidity and death rates, liver cancer has become one of the most common cancers in the world. But, most chemotherapeutic anticancer drugs have high toxicity as well as low specificity. To improve the treatment modalities and enhance the t
Externí odkaz:
https://doaj.org/article/aa8e8a73df354e11b365cece9fd0696c
Autor:
Xianling Gong, Zhihong Chen, Qinrui Han, Chunhui Chen, Linlin Jing, Yawei Liu, Liang Zhao, Xueqing Yao, Xuegang Sun
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
Abstract Background Previous studies showed sanguinarine induced apoptosis in CRC cells but did not define the underlying mechanisms. The purpose of this work was to determine the in vivo and in vitro effects of sanguinarine on CRC tumors and to eluc
Externí odkaz:
https://doaj.org/article/d765245c106149739260582c939bf6d7
Publikováno v:
Physical Chemistry Chemical Physics. 24:14947-14952
The reaction mechanisms of p-benzoquinone (PBQ) and tryptophan (Trp) were investigated and clarified, and the quenching rate constant was determined as 6.8 × 108 M−1 s−1, which close to the diffusion-controlled rate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::504a2c2ed5d0078ce93e50d495725521
https://doi.org/10.1039/d2cp01447e
https://doi.org/10.1039/d2cp01447e
Autor:
Xianling Gong, Ruibo Sun, Zhuowei Gao, Weili Han, Yawei Liu, Liang Zhao, Linlin Jing, Xueqing Yao, Xuegang Sun
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Macropinocytosis is a highly conserved endocytic process which characterizes the engulfment of extracellular fluid and its contents into cells via large, heterogeneous vacuoles known as macropinosomes. Tubeimoside-1 (TBM1) is a low toxic triterpenoid
Externí odkaz:
https://doaj.org/article/1667823fe1db484c8b5b9da670b569cb
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 595-603 (2019)
Drug Delivery
Drug Delivery
With high morbidity and death rates, liver cancer has become one of the most common cancers in the world. But, most chemotherapeutic anticancer drugs have high toxicity as well as low specificity. To improve the treatment modalities and enhance the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98cf52285643e3026b74a27ea83501ff
https://doaj.org/article/aa8e8a73df354e11b365cece9fd0696c
https://doaj.org/article/aa8e8a73df354e11b365cece9fd0696c
Autor:
Jun-Jiang Wang, Ye Ma, Xuegang Sun, Lu Li, Yiye Zhao, Wenjuan Xu, Linlin Jing, Xueqing Yao, Xianling Gong
Publikováno v:
Journal of Cell Communication and Signaling. 12:689-698
Colorectal cancer is generally believed to progress through an adenoma - carcinoma sequence. Adenomatous polyposis coli (APC) mutations serve as the initiating event in adenoma formation. The ApcMin/+ mouse harbors a mutation in the APC gene, which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb19e806d5c12765f1ec7737fe9570c3
https://doi.org/10.1007/s12079-018-0454-6
https://doi.org/10.1007/s12079-018-0454-6
Autor:
Qinrui Han, Xianling Gong, Chunhui Chen, Zhihong Chen, Linlin Jing, Yawei Liu, Liang Zhao, Xueqing Yao, Xuegang Sun
Publikováno v:
BMC Cancer
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
Background Previous studies showed sanguinarine induced apoptosis in CRC cells but did not define the underlying mechanisms. The purpose of this work was to determine the in vivo and in vitro effects of sanguinarine on CRC tumors and to elucidate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78be44dfabf9e3d46fd0fdbf1ec1ad2c
https://doi.org/10.1186/s12885-018-4463-x
https://doi.org/10.1186/s12885-018-4463-x
Autor:
J. Leung, Yingnian Lv, Ernest C.W. Chak, Li Li, Xianling Gong, Nian Ci Liang, George G. Chen, Ursula P. F. Chan, Billy C.S. Leung, Yi Feng Deng, Paul B.S. Lai, Jing Du, Mingyue Li, Kefeng Wu
Publikováno v:
Investigational New Drugs. 30:2210-2218
Ent-11-hydroxy-15-oxo-kaur-16-en-19-oic-acid (5F) isolated from Pteris Semipinnata L is known to inhibit certain tumor cells in vitro. The information on the in vivo effect of 5F is limited and its effect on hepatocellular carcinoma (HCC) is unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c283f4b86f7d02ac32984d40326df4
https://doi.org/10.1007/s10637-011-9791-5
https://doi.org/10.1007/s10637-011-9791-5
Autor:
Yingnian Lv, George G. Chen, Yi Feng Deng, Ming Yue Li, Nian Ci Liang, Kefeng Wu, J. Leung, Tony Mok, Xianling Gong, Angel W. Y. Kong, Malcolm J. Underwood, Michael K.Y. Hsin
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 88(12)
The mechanism responsible for the apoptotic effect induced by ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid (5F) is not fully understood and its in vivo effect has not been tested. In this study, the effect and mechanism of 5F was investigated in ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d203ed7308a6cae655ec1b146c6a8005
https://pubmed.ncbi.nlm.nih.gov/20830463
https://pubmed.ncbi.nlm.nih.gov/20830463