Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Xianjun, Zhu"'
Autor:
Kaifang Wang, Huijuan Xu, Rong Zou, Guangqun Zeng, Ye Yuan, Xianjun Zhu, Xiaohui Zhao, Jie Li, Lin Zhang
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Inherited retinal dystrophies (IRDs) are a group of debilitating visual disorders characterized by the progressive degeneration of photoreceptors, which ultimately lead to blindness. Among the causes of this condition, mutations i
Externí odkaz:
https://doaj.org/article/2a13d01ad60744988aa5297255f648af
Autor:
Wenjing Liu, Shujin Li, Mu Yang, Jie Ma, Lu Liu, Ping Fei, Qianchun Xiang, Lulin Huang, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu
Publikováno v:
eLife, Vol 13 (2024)
Familial exudative vitreoretinopathy (FEVR) is a severe genetic disorder characterized by incomplete vascularization of the peripheral retina and associated symptoms that can lead to vision loss. However, the underlying genetic causes of approximatel
Externí odkaz:
https://doaj.org/article/d74e1bf8c8cd48a5a233414b8dbc8fa7
Autor:
Xijun Luo, Hui Deng, Fei Xie, Liyan Wang, Junjie Liang, Xianjun Zhu, Tao Li, Xingkui Tang, Weixiong Liang, Zhiming Xiang, Jialin He
Publikováno v:
Translational Oncology, Vol 47, Iss , Pp 101997- (2024)
The liver is the most common organ for the formation of colorectal cancer metastasis. Non-invasive prognostication of colorectal cancer liver metastasis (CRLM) may better inform clinicians for decision-making. Contrast-enhanced computed tomography im
Externí odkaz:
https://doaj.org/article/2d709a6331784310a01ad813e2a62e57
Autor:
Guo Liu, Longxiang Huang, Junkai Tan, Yun Wang, Chunlin Lan, Yaxi Chen, Yukai Mao, Xizhen Wang, Ning Fan, Yihua Zhu, Xianjun Zhu, Xuyang Liu
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/2a697a00dad44490ae9b7fbbfa03db9c
Publikováno v:
MedComm, Vol 5, Iss 8, Pp n/a-n/a (2024)
Abstract Metabolic disorders, including obesity, dyslipidemia, diabetes, nonalcoholic fatty liver disease, and metabolic syndrome, are characterized by insulin resistance, abnormalities in circulating cholesterol and lipid profiles, and hypertension.
Externí odkaz:
https://doaj.org/article/cd33d490678d47ee9cc79fb35e5d36aa
Autor:
Kuanxiang Sun, Lu Liu, Xiaoyan Jiang, Heting Wang, Lin Wang, Yeming Yang, Wenjing Liu, Lin Zhang, Xiaohui Zhao, Xianjun Zhu
Publikováno v:
Genes and Diseases, Vol 11, Iss 2, Pp 1035-1049 (2024)
The endoplasmic reticulum (ER) membrane protein complex (EMC) is responsible for monitoring the biogenesis and synthetic quality of membrane proteins with tail-anchored or multiple transmembrane domains. The EMC subunit EMC6 is one of the core member
Externí odkaz:
https://doaj.org/article/38196c1721994bb3ae8ae8bb43ab0309
Autor:
Yanpei Hou, Sipei Chen, Lei Peng, Liming Huang, Huijian Zhang, Ping Zhang, Min Yu, Lin Xiong, Xiang Zhong, Wenjing Liu, Xianjun Zhu, Li Wang, Yi Li, Guisen Li
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109976- (2024)
Summary: Podocytopathies, such as focal segmental glomerulosclerosis (FSGS), are characterized by podocyte injury and can easily progress to end-stage kidney disease. However, the mechanisms underlying podocyte injury remain unclear. We observed podo
Externí odkaz:
https://doaj.org/article/c2da1e7268b64c8b9dd98ade3c31a212
Autor:
Shujin Li, Mu Yang, Rulian Zhao, Li Peng, Wenjing Liu, Xiaoyan Jiang, Yunqi He, Erkuan Dai, Lin Zhang, Yeming Yang, Yi Shi, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu
Publikováno v:
Genes and Diseases, Vol 10, Iss 6, Pp 2572-2585 (2023)
Endoplasmic reticulum (ER) membrane protein complex (EMC) is required for the co-translational insertion of newly synthesized multi-transmembrane proteins. Compromised EMC function in different cell types has been implicated in multiple diseases. Usi
Externí odkaz:
https://doaj.org/article/0c4f12a9a6714b3f8f53aa6ac4741f7a
Autor:
Xue Yang, Chun Gu, Jingshu Cai, Feiyang Li, Xing He, Lunan Luo, Wengan Xiao, Boyan Hu, Jing Hu, Hao Qian, Shangqing Ren, Lin Zhang, Xianjun Zhu, Lu Yang, Jing Yang, Zhenglin Yang, Yi Zheng, Xiang Huang, Ziyan Wang
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 103002- (2024)
Lipid peroxidation and redox imbalance are hallmarks of ferroptosis, an iron-dependent form of cell death. Growing evidence suggests that dysregulation in glycolipid metabolism and iron homeostasis substantially contribute to the development of hepat
Externí odkaz:
https://doaj.org/article/7610ac05aa394545a26eec5632e51a54
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-8 (2023)
Abstract The kidney reabsorbs large amounts of glucose through Na+-glucose cotransporter 2 (SGLT2). P4-ATPase acts together with the β-subunit TMEM30A to mediate the asymmetric distribution of phosphatidylserine (PS), phosphatidylethanolamine (PE),
Externí odkaz:
https://doaj.org/article/78f60afaf94d4ccb99b5e89d2c374ca3