Výsledky vyhledávání - "Xianheng WANG"

Akademický článek

Michael addition reaction in C-5 of Camptothecin

Autor: Changkuo Zhao, Linming Zuo, Xi Ke, Xianheng Wang

Publikováno v: Journal of Saudi Chemical Society, Vol 28, Iss 3, Pp 101867- (2024)

A simple method for Michael addition at C-5 of Camptothecin has been developed to construct 5-CPT derivatives. The addition products were obtained with moderate yields, and the structures of the target compounds were characterized by 1H NMR, 13C NMR,

Externí odkaz: https://doaj.org/article/4b5c526972024d4ca972f650ec78253e

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Akademický článek

Three-step synthetic procedure to prepare dolutegravir, cabotegravir, and bictegravir

Autor: Xianheng Wang, Song Chen, Hanqi Cui, Yuqi He, Changkuo Zhao

Publikováno v: Green Chemistry Letters and Reviews, Vol 15, Iss 2, Pp 312-319 (2022)

Dolutegravir, cabotegravir, and bictegravir are three integrase inhibitors, which were used for HIV-1 in the clinic. In this paper, a continuous three-step synthetic strategy was developed to prepare dolutegravir, cabotegravir, and bictegravir in a b

Externí odkaz: https://doaj.org/article/1cbe372ee7ad41fb8d32c7fd6a278cc6

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Akademický článek

Impact-induced bonding process of copper at low velocity and room temperature

Autor: Cong Chen, Hao Su, Xianheng Wang, Yan Liu, LeiYang Zhao, Xinqi Wei, Yuzhen Zhao, Jiacong Pan, Xinming Qiu

Publikováno v: Materials & Design, Vol 226, Iss , Pp 111603- (2023)

The impact-induced bonding can be foundation of fast solid-state additive manufacturing. The mechanisms behind impact-induced bonding have not been widely acknowledged due to complexity caused by too transient process and extreme loading conditions.

Externí odkaz: https://doaj.org/article/7c8fa8382c314e3eaf90424d99bb5187

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Akademický článek

NBS promoted cascade reaction of β-anhydroicaritine and alcohols

Autor: Hanqi Cui, Xianheng Wang, Shuang Qian, Yuqi He, Changkuo Zhao

Publikováno v: Green Chemistry Letters and Reviews, Vol 16, Iss 1 (2023)

ABSTRACTAn unusual NBS promoted cascade reaction of β-anhydroicaritine and alcohols was successfully developed to prepare chromane-3,4-dione 3 in a moderate yield. A mechanism was also put forward to explain this reaction. These chromane-3,4-dione d

Externí odkaz: https://doaj.org/article/1307d03ed0b546ffaf50ee7ff949f09d

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Akademický článek

A simple route to a novel acid-sensitive 20(S)-O-linked camptothecin norcantharidin acid ester derivative

Autor: Changkuo Zhao, Xianheng Wang, Fuhong Yang, Lei Gao, Yuhe Wang

Publikováno v: Royal Society Open Science, Vol 5, Iss 2 (2018)

A facile synthetic method was developed for a novel acid-sensitive camptothecin norcantharidin acid ester derivative I. The total yield can reach 71%. This method provides several advantages, including high yield and simple working procedure for the

Externí odkaz: https://doaj.org/article/087f15514f1249cd835f4d596132f9d6

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