Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Xiangyuan, He"'
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
Objective. To investigate the effect and mechanism of curcumin (CUR) killing lung cancer HCC827 cell spheres. Method. HCC827 cell spheres were cultured in serum-free medium, and the protein expression of CD133, SOX2, EpCAM, and ABCG2 was detected by
Externí odkaz:
https://doaj.org/article/dd7c738d08564a909b23369c2f652c1d
Autor:
Guangyu Zhu, Nancy Wakeham, Xuejun C. Zhang, Karla K. Rodgers, Peng Zhai, Guangpu Li, Xiangyuan He, Jordan Tang
Publikováno v:
The EMBO Journal. 23:3909-3917
GGA proteins coordinate the intracellular trafficking of clathrin-coated vesicles through their interaction with several other proteins. The GAT domain of GGA proteins interacts with ARF, ubiquitin, and Rabaptin5. The GGA-Rabaptin5 interaction is bel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d41c263668ddd9d4b3f6d35502381ed
https://doi.org/10.1038/sj.emboj.7600411
https://doi.org/10.1038/sj.emboj.7600411
Autor:
Xuejun C. Zhang, Guangyu Zhu, Jian Liu, Guangpu Li, Nancy Wakeham, Xiangyuan He, Jordan Tang, Peng Zhai
Publikováno v:
Biochemistry. 42:13901-13908
GGA proteins regulate clathrin-coated vesicle trafficking by interacting with multiple proteins during vesicle assembly. As part of this process, the GAT domain of GGA is known to interact with both ARF and Rabaptin-5. Particularly, the GAT domains o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ed84064095cbe4f4a189ed1f0278b7
https://doi.org/10.1021/bi035392b
https://doi.org/10.1021/bi035392b
Publikováno v:
Biochemistry. 42:12174-12180
Memapsin 2 (beta-secretase) is a membrane-associated aspartic protease that initiates the hydrolysis of beta-amyloid precursor protein (APP) leading to the production of amyloid-beta and the onset of Alzheimer's disease (AD). Both memapsin 2 and APP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca174d3dd15a1b549f5012ff8832470
https://doi.org/10.1021/bi035199h
https://doi.org/10.1021/bi035199h
Autor:
Guangyu Zhu, Rongguang Zhang, Peng Zhai, Andrzej Joachimiak, Simon Terzyan, Xiangyuan He, Jordan Tang, Xuejun C. Zhang
Publikováno v:
Biochemistry. 42:6392-6399
GGAs are a family of vesicle-coating regulatory proteins that function in intracellular protein transport. A GGA molecule contains four domains, each mediating interaction with other proteins in carrying out intracellular transport. The GAT domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc538bf43f422fb6647d0029af1419e6
https://doi.org/10.1021/bi034334n
https://doi.org/10.1021/bi034334n
Publikováno v:
FEBS Letters. 524:183-187
Memapsin 2, or beta-secretase, is a membrane-anchored aspartic protease that initiates the cleavage of beta-amyloid precursor protein (APP) leading to the production of beta-amyloid peptide in the brain and the onset of Alzheimer's disease. Memapsin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1c77424b2afb072d6538c17f3cd6bd
https://doi.org/10.1016/s0014-5793(02)03052-1
https://doi.org/10.1016/s0014-5793(02)03052-1
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(15)
The homeostasis of amyloid-beta (Abeta) in the brain is critical to the pathogenesis of Alzheimer's disease (AD). Abeta is a fragment of amyloid-beta precursor protein (APP) generated in neurons by two proteases, beta- and gamma-secretases. APP and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af346a20b19b1997192d73aae56aa7a1
https://pubmed.ncbi.nlm.nih.gov/17428983
https://pubmed.ncbi.nlm.nih.gov/17428983
Publikováno v:
Methods in enzymology. 403
GGAs are a family of adaptor proteins involved in vesicular transport. As an effector of the small GTPase Arf, GGA interacts using its GAT domain with the GTP-bound form of Arf. The GAT domain is also found to interact with ubiquitin and rabaptin-5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::90ed1279f0d6f31fa727b3c91eab23c4
https://pubmed.ncbi.nlm.nih.gov/16473621
https://pubmed.ncbi.nlm.nih.gov/16473621
GGAs are a family of adaptor proteins involved in vesicular transport. As an effector of the small GTPase Arf, GGA interacts using its GAT domain with the GTP‐bound form of Arf. The GAT domain is also found to interact with ubiquitin and rabaptin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e7fcade08cc469feea4caf6df423b9
https://doi.org/10.1016/s0076-6879(05)03050-8
https://doi.org/10.1016/s0076-6879(05)03050-8
Publikováno v:
The Journal of biological chemistry. 280(12)
Memapsin 2 (BACE, beta-secretase) is a membrane-associated aspartic protease that initiates the hydrolysis of beta-amyloid precursor protein (APP) leading to the production of amyloid-beta (A beta) and the progression of Alzheimer disease. Both memap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f1c7fd5969619fe4bfcf3a789a9fed
https://pubmed.ncbi.nlm.nih.gov/15615712
https://pubmed.ncbi.nlm.nih.gov/15615712