Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Xiangxue Guo"'
Autor:
Yan Lü, Yulin Jiang, Xiya Zhou, Na Hao, Guizhen Lü, Xiangxue Guo, Ruidong Guo, Wenjie Liu, Chenlu Xu, Jiazhen Chang, Mengmeng Li, Hanzhe Zhang, Jing Zhou, Wei (Victor) Zhang, Qingwei Qi
Publikováno v:
Diagnostics, Vol 13, Iss 3, p 560 (2023)
Objective: Absence of homozygosity (AOH) is a genetic characteristic known to cause human diseases mainly through autosomal recessive or imprinting mechanisms. The importance and necessity of accurate AOH detection has become more clinically signific
Externí odkaz:
https://doaj.org/article/91e683b5e4e54e4aa40718e40177b55f
Autor:
Ha Eun, Kong, Junghwa, Lim, Alexander, Linsalata, Yunhee, Kang, Indranil, Malik, Emily G, Allen, Yiqu, Cao, Lisa, Shubeck, Rich, Johnston, Yanting, Huang, Yanghong, Gu, Xiangxue, Guo, Michael E, Zwick, Zhaohui, Qin, Thomas S, Wingo, Jorge, Juncos, David L, Nelson, Michael P, Epstein, David J, Cutler, Peter K, Todd, Stephanie L, Sherman, Stephen T, Warren, Peng, Jin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(22)
Fragile X–associated tremor/ataxia syndrome (FXTAS) is a debilitating late-onset neurodegenerative disease in premutation carriers of the expanded CGG repeat in FMR1 that presents with a spectrum of neurological manifestations, such as gait ataxia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41085d2235672607c137326ca7ff6f70
https://pubmed.ncbi.nlm.nih.gov/35617426
https://pubmed.ncbi.nlm.nih.gov/35617426
Autor:
Ha Eun Kong, Junghwa Lim, Alexander Linsalata, Yunhee Kang, Indranil Malik, Emily G. Allen, Yiqu Cao, Lisa Shubeck, Rich Johnston, Yanting Huang, Yanghong Gu, Xiangxue Guo, Michael E. Zwick, Zhaohui Qin, Thomas S. Wingo, Jorge Juncos, David L. Nelson, Michael P. Epstein, David J. Cutler, Peter K. Todd, Stephanie L. Sherman, Stephen T. Warren, Peng Jin
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance Expansion of 55-200 CGG repeats in the 5′ untranslated region of FMR1 predisposes carriers to fragile X–associated tremor/ataxia syndrome (FXTAS), a late-onset neurodegenerative disorder. FXTAS demonstrates incomplete penetrance, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1df20e3bb38f81d058ee328019f3f9f3
https://doi.org/10.1073/pnas.2118124119
https://doi.org/10.1073/pnas.2118124119
Autor:
Xiangxue Guo, Hui Mao, Y. Andrew Wang, Erica N. Bozeman, Toncred M. Styblo, Ruth O'Regan, Xin Ji, Weiping Qian, Hongyu Zhou, Jasmine Miller-Kleinhenz, Lily Yang, Lei Zhu
Publikováno v:
Biomaterials. 152:47-62
Heterogeneous tumor cells, high incidence of tumor recurrence, and decrease in overall survival are the major challenges for the treatment of chemo-resistant breast cancer. Results of our study showed differential chemotherapeutic responses among bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fe3b9a42e75c7f84cce4184c2de4bc
https://doi.org/10.1016/j.biomaterials.2017.10.035
https://doi.org/10.1016/j.biomaterials.2017.10.035
Autor:
Zhengjia Chen, Haian Fu, Leon Bernal-Mizrachi, Sampath Ramachandiran, Arsene M. Adon, Ustun R. Sunay, Karen P. Mann, Jessica C. Mar, Andrew N. Young, Yuhong Du, Huichen Wang, Xiangxue Guo, Izidore S. Lossos, Lawrence H. Boise, Yi Wang, Jeanne Kowalski, Yasodha Natkunam, Harold I. Saavedra, Theresa Brown
Publikováno v:
International Journal of Cancer. 136:2341-2351
Diffuse large B cell lymphoma (DLBCL) is the most common form of lymphoma in the United States. DLBCL comprises biologically distinct subtypes including germinal center-like (GCB) and activated-B-cell-like DLBCL (ABC). The most aggressive type, ABC-D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::573a8811774be5d234540cf0e2989e4d
https://doi.org/10.1002/ijc.29301
https://doi.org/10.1002/ijc.29301
Autor:
Zhengjia Chen, Leon Bernal-Mizrachi, Jean L. Koff, Marina Mosunjac, Lawrence H. Boise, Sandeep S. Dave, Xiangxue Guo, Andrea B. Moffitt, Mahir Bagirov, Jeanne Kowalski, Christopher R. Flowers, Stuart Neill, Yasodha Natkunam, Jeffrey M. Switchenko, Sampath Ramachandiran, Yuhong Du, H.J. Khoury, I. S. Lossos, Michael R. Rossi, Wayne Harris, Munevver Cinar, Karen P. Mann
Publikováno v:
Oncogene. 36(29)
Diffuse large B-cell lymphoma (DLBCL) has been categorized into two molecular subtypes that have prognostic significance, namely germinal center B-cell like (GCB) and activated B-cell like (ABC). Although ABC-DLBCL has been associated with NF-κB act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a547c81301ac1f99d1c731473790cc6f
https://pubmed.ncbi.nlm.nih.gov/28368397
https://pubmed.ncbi.nlm.nih.gov/28368397
Autor:
Albert Liao, Lawrence H. Boise, Xiangxue Guo, Hanna Jean Khoury, Yanjuan He, Leon Bernal-Mizrachi, Lee Ratner, Haian Fu, Joan Cain, Sampath Ramachandiran
Publikováno v:
Leukemia Research. 36:784-790
The inhibitors of apoptosis (IAP) are important regulators of apoptosis. However, little is known about the capacity of Smac mimetics (IAP inhibitor) to overcome virally associated-lymphoma's (VAL) resistance to apoptosis. Here, we explored the pro-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e6f8ec8254107239ad33292e8723f1
https://doi.org/10.1016/j.leukres.2011.12.024
https://doi.org/10.1016/j.leukres.2011.12.024
Autor:
H. Jean Khoury, Lin Pan, Martha Arellano, Zhengjia Chen, Amelia Langston, Georgia Z. Chen, Xiangxue Guo, Mourad Tighiouart, Lisa Lima, Liliana Souza, Susan Sunay, Morgan L. McLemore, Leonard T. Heffner, Elliott F. Winton, Leon Bernal-Mizrachi
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 11:427-432
We investigated the clinical significance of leukopenia at the time of diagnosis in a cohort of 225 patients with newly diagnosed acute myeloid leukemia (AML) at a single institution. Leukocyte count was treated as a continuous variable and, using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecc68e08e2f8de98bad2956148a29a4
https://doi.org/10.1016/j.clml.2011.03.035
https://doi.org/10.1016/j.clml.2011.03.035
Autor:
Jan Mrázek, Xiangxue Guo
Publikováno v:
Journal of Molecular Evolution. 67:497-509
Simple sequence repeats (SSRs) in DNA sequences are tandem iterations of a single nucleotide or a short oligonucleotide. SSRs are subject to slipped-strand mutations and a common source of phase variation in bacteria and antigenic variation in pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4da5b243609e93062dec0a7d3bb0ea
https://doi.org/10.1007/s00239-008-9166-5
https://doi.org/10.1007/s00239-008-9166-5
Publikováno v:
Biochemistry. 45:14473-14480
The cytoplasmic membrane protein CvaB, involved in colicin V secretion in Escherichia coli, belongs to the ABC-transporter family in which ATP hydrolysis is typically the driving force for substrate transport. However, our previous studies indicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ced54a84bcc4ebca2e3cffb27aba2c1
https://doi.org/10.1021/bi061506i
https://doi.org/10.1021/bi061506i