Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xiangshi Sun"'
Autor:
Shiyan Dong, Xuan Liu, Ye Bi, Yifan Wang, Abin Antony, DaeYong Lee, Kristin Huntoon, Seongdong Jeong, Yifan Ma, Xuefeng Li, Weiye Deng, Benjamin R. Schrank, Adam J. Grippin, JongHoon Ha, Minjeong Kang, Mengyu Chang, Yarong Zhao, Rongze Sun, Xiangshi Sun, Jie Yang, Jiayi Chen, Sarah K. Tang, L. James Lee, Andrew S. Lee, Lirong Teng, Shengnian Wang, Lesheng Teng, Betty Y. S. Kim, Zhaogang Yang, Wen Jiang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The recent success of mRNA therapeutics against pathogenic infections has increased interest in their use for other human diseases including cancer. However, the precise delivery of the genetic cargo to cells and tissues of interest remains
Externí odkaz:
https://doaj.org/article/daa7ff6703414ccab6b6c9e5982dab8f
Autor:
Xiangshi Sun, Xiaoxuan Xu, Jue Wang, Xinyue Zhang, Zitong Zhao, Xiaochen Liu, Guanru Wang, Lesheng Teng, Xia Chen, Dangge Wang, Yaping Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 7, Pp 3093-3105 (2023)
Deficiency of natural killer (NK) cells shows a significant impact on tumor progression and failure of immunotherapy. It is highly desirable to boost NK cell immunity by upregulating active receptors and relieving the immunosuppressive tumor microenv
Externí odkaz:
https://doaj.org/article/f5afbfb38faa4fff8db2ddee90c7038e
Autor:
Wenzhe Yi, Ping Xiao, Xiaochen Liu, Zitong Zhao, Xiangshi Sun, Jue Wang, Lei Zhou, Guanru Wang, Haiqiang Cao, Dangge Wang, Yaping Li
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-25 (2022)
Abstract Bioorthogonal chemistry reactions occur in physiological conditions without interfering with normal physiological processes. Through metabolic engineering, bioorthogonal groups can be tagged onto cell membranes, which selectively attach to c
Externí odkaz:
https://doaj.org/article/e050ae023adf45918874ce46faec51c4
Autor:
Lei Fang, Zitong Zhao, Jue Wang, Ping Xiao, Xiangshi Sun, Yaping Ding, Pengcheng Zhang, Dangge Wang, Yaping Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 353-363 (2022)
Nucleic acid drugs are highly applicable for cancer immunotherapy with promising therapeutic effects, while targeting delivery of these drugs to disease lesions remains challenging. Cationic polymeric nanoparticles have paved the way for efficient de
Externí odkaz:
https://doaj.org/article/fe3aa1eb47a240b2b705605c407a75ba
Autor:
Ping Xiao, Xiangshi Sun, Lei Fang, Pengcheng Zhang, Jue Wang, Dangge Wang, Yaping Li, Zitong Zhao, Yaping Ding
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 353-363 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Nucleic acid drugs are highly applicable for cancer immunotherapy with promising therapeutic effects, while targeting delivery of these drugs to disease lesions remains challenging. Cationic polymeric nanoparticles have paved the way for efficient de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428c0473fc726884308ff2ab0dca4053
http://www.sciencedirect.com/science/article/pii/S2211383521002185
http://www.sciencedirect.com/science/article/pii/S2211383521002185
Publikováno v:
Small Methods. 7
Photodynamic therapy (PDT)-mediated cancer immunotherapy is attenuated due to the dysfunction of T cells in immunosuppressive tumor microenvironment (TME). Cholesterol metabolism plays a vital role in T cell signaling and effector. While the metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae3a7967eadbee2b62f26a23e01faac
https://doi.org/10.1002/smtd.202200898
https://doi.org/10.1002/smtd.202200898
Autor:
Zitong Zhao, Lei Fang, Ping Xiao, Xiangshi Sun, Lei Zhou, Xiaochen Liu, Jue Wang, Guanru Wang, Haiqiang Cao, Pengcheng Zhang, Yanyan Jiang, Dangge Wang, Yaping Li
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 34(33)
Lung metastasis is challenging in patients with triple-negative breast cancer (TNBC). Surgery is always not available due to the dissemination of metastatic foci and most drugs are powerless because of poor retention at metastatic sites. TNBC cells g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2aaa2d9bf8ee200e2ae654bd2de2fa
https://pubmed.ncbi.nlm.nih.gov/35759925
https://pubmed.ncbi.nlm.nih.gov/35759925
Publikováno v:
Nano Letters. 21:2094-2103
Nanoscale artificial antigen-presenting cells (aAPCs) are promising to activate T cells directly for cancer immunotherapy, while feasible and flexible strategy to develop nanoscale aAPCs remains highly desirable. Metabolic glycoengineering is used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f10b52bc1649c63a1a16d47ab9b700
https://doi.org/10.1021/acs.nanolett.0c04783
https://doi.org/10.1021/acs.nanolett.0c04783
Autor:
Shiyan Dong, Ye Bi, Xiangshi Sun, Yarong Zhao, Rongze Sun, Fei Hao, Yating Sun, Yifan Wang, Xuefeng Li, Weiye Deng, Xuan Liu, JongHoon Ha, Lirong Teng, Ping Gong, Jing Xie, Betty Y. S. Kim, Zhaogang Yang, Wen Jiang, Lesheng Teng
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 18(16)
Triple-negative breast cancer (TNBC) is the most lethal subtypes of breast cancer. Although chemotherapy is considered the most effective strategy for TNBC, most chemotherapeutics in current use are cytotoxic, meaning they target antiproliferative ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473d52823af7ab5fdefe7ecf729ae144
https://pubmed.ncbi.nlm.nih.gov/35277914
https://pubmed.ncbi.nlm.nih.gov/35277914
Autor:
Chaoxing long, Fengying Sun, Xueyan Zhang, Jiaxin Liu, Changhui Yu, Robert J. Lee, Lesheng Teng, Xiangshi Sun, Na Liu, Youxin Li, Xiangyu Li
Publikováno v:
International Journal of Pharmaceutics. 552:148-153
Ketoprofen, a non-steroid anti-inflammatory drug, is widely used for relieving the pain and swelling caused by rheumatoid arthritis. However, ketoprofen can't suppress disease progression effectively. In this study, in an effort to improve the therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a33a2e5cb35506b08a005789267d2b
https://doi.org/10.1016/j.ijpharm.2018.09.063
https://doi.org/10.1016/j.ijpharm.2018.09.063