Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Xiangrui, Jiang"'
Autor:
Xiangrui Jiang, Haixia Su, Weijuan Shang, Feng Zhou, Yan Zhang, Wenfeng Zhao, Qiumeng Zhang, Hang Xie, Lei Jiang, Tianqing Nie, Feipu Yang, Muya Xiong, Xiaoxing Huang, Minjun Li, Ping Chen, Shaoping Peng, Gengfu Xiao, Hualiang Jiang, Renhong Tang, Leike Zhang, Jingshan Shen, Yechun Xu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The persistent pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants accentuates the great demand for developing effective therapeutic agents. Here, we report
Externí odkaz:
https://doaj.org/article/a28e5c09138247129c790be1234763fd
Autor:
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hangping Yao, Weiliang Zhu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-8 (2023)
Abstract Effective drugs with broad spectrum safety profile to all people are highly expected to combat COVID-19 caused by SARS-CoV-2. Here we report that nelfinavir, an FDA approved drug for the treatment of HIV infection, is effective against SARS-
Externí odkaz:
https://doaj.org/article/cbeb9c93ea5442cba5846201420e2c42
Autor:
Shavkat I. Salikhov, Ibrokhim Y. Abdurakhmonov, Yuliya I. Oshchepkova, Jamolitdin F. Ziyavitdinov, Nodir Sh. Berdiev, Haji Akber Aisa, Jingshan Shen, Yechun Xu, H. Eric Xu, Xiangrui Jiang, Leike Zhang, Natalia L. Vypova, Dilshod Sh. Allaberganov, Nigora A. Tagayalieva, Erkin I. Musabaev, Gulnara A. Ibadova, Ilxom B. Rajabov, Lyubov M. Lokteva
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Previously, from the tannic sumac plant (Rhus coriaria), we developed the Rutan 25 mg oral drug tablets with antiviral activity against influenza A and B viruses, adenoviruses, paramyxoviruses, herpes virus, and cytomegalovirus. Here, our re-purposin
Externí odkaz:
https://doaj.org/article/8dfb66c2f40449c8a848cd89e71ebd15
Autor:
Fuxiang Wang, Wen Xiao, Yimin Tang, Mengli Cao, Dan Shu, Tetsuya Asakawa, Yechun Xu, Xiangrui Jiang, Leike Zhang, Wei Wang, Jianxing Tang, Yuansheng Huang, Yang Yang, Yumei Yang, Renhong Tang, Jingshan Shen, Hongzhou Lu
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 38, Iss , Pp 100835- (2023)
Summary: Background: SIM0417 (SSD8432) is an orally administered coronavirus main proteinase (3CLpro) inhibitor with potential anti-SARS-CoV-2 activity. This study aimed to evaluate the efficacy and safety of SIM0417 plus ritonavir (a pharmacokinetic
Externí odkaz:
https://doaj.org/article/e5cbb5b842784fa9b314a8ee813b9849
Autor:
Haixia Su, Sheng Yao, Wenfeng Zhao, Yumin Zhang, Jia Liu, Qiang Shao, Qingxing Wang, Minjun Li, Hang Xie, Weijuan Shang, Changqiang Ke, Lu Feng, Xiangrui Jiang, Jingshan Shen, Gengfu Xiao, Hualiang Jiang, Leike Zhang, Yang Ye, Yechun Xu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
SARS-CoV-2 3CL protease (3CLpro) is essential for coronavirus replication and of great interest as an antiviral drug target. Here, the authors show that the naturally occurring flavonoid myricetin is a non-peptidomimetic and covalent inhibitor of 3CL
Externí odkaz:
https://doaj.org/article/ff68234682c746f3aa209aef3785fbf8
Autor:
Debin Zou, Mingyang Yu, Xiangrui Jiang, Na Zhao, Tongpu Yu, Hongbin Zhuo, Alexander Pukhov, Yanyun Ma, Fuqiu Shao, Cangtao Zhou, Shuangchen Ruan
Publikováno v:
Advanced Photonics Research, Vol 2, Iss 7, Pp n/a-n/a (2021)
Energetic heavy ions with short duration can be generated in the interaction of ultrashort ultraintense (USUI) laser pulse with solid matter. However, the energy conversion efficiency from laser to heavy ions is usually very low. Herein, a novel sche
Externí odkaz:
https://doaj.org/article/5666e977dfab4d74baebbd4220e1bc5c
Autor:
Wu He, Gang Yuan, Yu Han, Yongcui Yan, Gen Li, Chengcheng Zhao, Jingshan Shen, Xiangrui Jiang, Chen Chen, Li Ni, Dao Wen Wang
Publikováno v:
European Journal of Preventive Cardiology. 30:474-487
Aims Glimepiride has good cardiovascular safety. However, whether glimepiride benefits clinical cardiovascular outcomes is unclear. Methods and results A total of 21 451 inpatients with type 2 diabetes (T2D) and chronic heart failure (CHF) were analy
Autor:
Liyuan Peng, Ziping Song, Chengcheng Zhao, Kudusi Abuduwufuer, Yanwen Wang, Zheng Wen, Li Ni, Chenze Li, Ying Yu, Yi Zhu, Hualiang Jiang, Jinshan Shen, Xiangrui Jiang, Chen Chen, Xu Zhang, Dao Wen Wang
Publikováno v:
Phenomics. 3:34-49
Autor:
Salikhov, Shavkat I., Abdurakhmonov, Ibrokhim Y., Oshchepkova, Yuliya I., Ziyavitdinov, Jamolitdin F., Berdiev, Nodir Sh., Aisa, Haji Akber, Jingshan Shen, Yechun Xu, Xu, H. Eric, Xiangrui Jiang, Leike Zhang, Vypova, Natalia L., Allaberganov, Dilshod Sh., Tagayalieva, Nigora A., Musabaev, Erkin I., Ibadova, Gulnara A., Rajabov, Ilxom B., Lokteva, Lyubov M.
Publikováno v:
Frontiers in Medicine; 2023, p1-13, 13p
Publikováno v:
Journal of Carbohydrate Chemistry. 41:18-27
A new route for the synthesis of tetrahydrocortisone 3-glucuronide has been developed with cortisone acetate as a starting material. The key step was using lithium tri-tert-butoxyaluminum hydride to reduce the C-3 carbonyl group of 5��-dihydrocor