Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Xiangru Lai"'
Autor:
Ying Shi, Lili Yan, Yuyan Wang, Naiming Zhou, Lingyan Ye, Xiangru Lai, Zhiqiang Guo, Weiwei Wang, Zheng Cao
Publikováno v:
The FASEB Journal. 33:4765-4779
The incidence of overweight and obesity has become a global public health problem, constituting a major risk factor for numerous comorbidities. Despite tremendous efforts, effective pharmacological agents for the treatment of obesity are still limite
Publikováno v:
The Journal of nutrition. 150(4)
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in the world. Hepatic de novo lipogenesis (DNL) has been suggested to contribute to the pathogenesis of NAFLD. Recent studies have demonstrated that niacin (NA) modu
Autor:
Xiangru Lai, Bin Lu, Ying Shi, Qiang Ma, Gang Wu, Yuan Liao, Jiashu Zang, Dongxiang Liu, Feng Han, Naiming Zhou
Publikováno v:
Journal of Biological Chemistry. 291:7505-7516
Human neuropeptide S (NPS) and its cognate receptor regulate important biological functions in the brain and have emerged as a future therapeutic target for treatment of a variety of neurological and psychiatric diseases. The human NPS (hNPS) recepto
Publikováno v:
International Journal of Earth Sciences. 105:1563-1589
Late Mesozoic magmatic rocks from the Taishanmiao Batholith were collected for LA–ICP–MS dating, Sr–Nd–Hf isotope systematics, and whole-rock major and trace element geochemistry to help understand the nature of collisional and extensional ev
Autor:
Jun Deng, M. Santosh, Chunying Guo, Rui Xia, Qingjie Gong, Emmanuel John M. Carranza, Changming Wang, Xiangru Lai
Publikováno v:
Ore Geology Reviews. 65:659-673
The Xincheng gold deposit located at the northwestern edge of the Jiaodong Peninsula in the North China Craton has a reserve of ~ 96 t Au and is among the largest in the Jiaodong gold province. Here, disseminated- and stockwork-style ores are hosted
Autor:
Keqiang Chen, Mingyong Liu, Ying Shi, Ji Ming Wang, Yuan Liao, Lili Jin, Chunyan Wang, Lingyan Ye, Zheng Cao, Naiming Zhou, Wanghua Gong, Xiangru Lai
Publikováno v:
Scientific Reports
The niacin receptor HCA2 is implicated in controlling inflammatory host responses with yet poorly understood mechanistic basis. We previously reported that HCA2 in A431 epithelial cells transduced Gβγ-protein kinase C- and Gβγ-metalloproteinase/E
Publikováno v:
Ore Geology Reviews. 56:327-351
In China, sediment-hosted Pb―Zn deposits represent a significant type of base-metal deposits are major sources of Pb and Zn and significant sources of Ag and Ge. In this paper, we focus discussion on MVT (Mississippi Valley type), SEDEX (sedimentar
Autor:
Bing Lu, Yuan Liao, Lili Jin, Yi Sun, Xiangru Lai, Lingyan Ye, Naiming Zhou, Ying Shi, Qiang Ma
Publikováno v:
Journal of neurochemistry. 137(2)
The histamine H3 receptor (H3R), abundantly expressed in the central and the peripheral nervous system, has been recognized as a promising target for the treatment of various important CNS diseases including narcolepsy, Alzheimer's disease, and atten
Autor:
Lingyan Ye, Zheng Cao, Xiangru Lai, Weiwei Wang, Zhiqiang Guo, Lili Yan, Yuyan Wang, Ying Shi, Naiming Zhou
Publikováno v:
FASEB Journal; Apr2019, Vol. 33 Issue 4, p4765-4779, 15p
Autor:
Ying Shi, Xiaobai He, Xiaopan Chen, Jiajie Shao, Linjie Chen, Naiming Zhou, Xiangru Lai, Yaping Zhang
Publikováno v:
Biochemistry. 53(17)
The pineal gland hormone melatonin exerts its regulatory roles in a variety of physiological and pathological responses through two G protein-coupled receptors, melatonin receptor type 1 (MT1) and melatonin receptor type 2 (MT2), which have been reco