Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Xiangnan Guan"'
Autor:
Thomas C. Westbrook, Xiangnan Guan, Eva Rodansky, Diana Flores, Chia Jen Liu, Aaron M. Udager, Radhika A. Patel, Michael C. Haffner, Ya-Mei Hu, Duanchen Sun, Tomasz M. Beer, Adam Foye, Rahul Aggarwal, David A. Quigley, Jack F. Youngren, Charles J. Ryan, Martin Gleave, Yuzhuo Wang, Jiaoti Huang, Ilsa Coleman, Colm Morrissey, Peter S. Nelson, Christopher P. Evans, Primo Lara, Robert E. Reiter, Owen Witte, Matthew Rettig, Christopher K. Wong, Alana S. Weinstein, Vlado Uzunangelov, Josh M. Stuart, George V. Thomas, Felix Y. Feng, Eric J. Small, Joel A. Yates, Zheng Xia, Joshi J. Alumkal
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Lineage plasticity is increasingly recognized as an emergent resistance mechanism after treatment with androgen receptor signalling inhibitors. To understand determinants of resistance, the authors analyzed the transcriptomes of patient tumor biopsie
Externí odkaz:
https://doaj.org/article/84a852fcb0624999ab330bdca23f4d3f
Autor:
Kamalakannan Rajasekaran, Xiangnan Guan, Alireza Tafazzol, Habib Hamidi, Martine Darwish, Mahesh Yadav
Publikováno v:
Translational Oncology, Vol 27, Iss , Pp 101559- (2023)
Background: Recent advances in single-cell technologies and an improved understanding of tumor antigens have empowered researchers to investigate tumor antigen-specific CD8+ T cells at the single-cell level. Peptide-MHC I tetramers are often utilized
Externí odkaz:
https://doaj.org/article/2c46d971ad4c4375b7ee0e590ee03894
Autor:
Andrew Wallace, Deepali Rishipathak, Mahesh Yadav, Sanjeev Mariathasan, Evan W Newell, Alessandra Nardin, Oliver A Zill, Michael Fehlings, Leesun Kim, Xiangnan Guan, Kobe Yuen, Alireza Tafazzol, Shomyseh Sanjabi, Siming Ma, Ana Milojkovic
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background A growing body of evidence suggests that T-cell responses against neoantigens are critical regulators of response to immune checkpoint blockade. We previously showed that circulating neoantigen-specific CD8 T cells in patients with lung ca
Externí odkaz:
https://doaj.org/article/1b1d22e3dd284708b9bfcaa707c18a5e
Autor:
Ashish N. Rao, Hannah M. Campbell, Xiangnan Guan, Tarah A. Word, Xander H.T. Wehrens, Zheng Xia, Thomas A. Cooper
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
Myotonic dystrophy type 1 (DM1) is caused by a CTG repeat expansion in the DMPK gene. Expression of pathogenic expanded CUG repeat (CUGexp) RNA causes multisystemic disease by perturbing the functions of RNA-binding proteins, resulting in expression
Externí odkaz:
https://doaj.org/article/57ad09e152f94a3589084046d23de525
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Apple ring rot caused by Botryosphaeria dothidea is an important disease in China, which leads to serious economic losses during storage. Plant activators are compounds that induce resistance against pathogen infection and are considered as a promisi
Externí odkaz:
https://doaj.org/article/990126deb65141be91897b1bf99305a4
Publikováno v:
The Scientific World Journal, Vol 2013 (2013)
Valsa mali is a causal agent of apple and pear trees canker disease, which is a destructive disease that causes serious economic losses in eastern Asia, especially in China. The lack of an efficient transformation system for Valsa mali retards its in
Externí odkaz:
https://doaj.org/article/3a2cf0fa74714c82814422adbb06fbe0
Autor:
Christin E. Burd, Jianying Zhang, Reena Shakya, Christina Y. Yu, Rebecca C. Hennessey, Kyle M. LaPak, Xiangnan Guan
Real-time PCR hit validation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c3a95c89975fb1160563ffe2b7cf3d
https://doi.org/10.1158/1541-7786.22511602
https://doi.org/10.1158/1541-7786.22511602
Autor:
Christin E. Burd, Jianying Zhang, Reena Shakya, Christina Y. Yu, Rebecca C. Hennessey, Kyle M. LaPak, Xiangnan Guan
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16610c6825bd2ace4458dbaf4fa8142e
https://doi.org/10.1158/1541-7786.22511590
https://doi.org/10.1158/1541-7786.22511590
Supplemental Table 1 from Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth
Autor:
Christin E. Burd, Jianying Zhang, Reena Shakya, Christina Y. Yu, Rebecca C. Hennessey, Kyle M. LaPak, Xiangnan Guan
Real-time PCR primer sets for the analysis of SASP gene expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1372adcf31bc1e7e69a0db72c538a18f
https://doi.org/10.1158/1541-7786.22511593.v1
https://doi.org/10.1158/1541-7786.22511593.v1
Autor:
Christin E. Burd, Jianying Zhang, Reena Shakya, Christina Y. Yu, Rebecca C. Hennessey, Kyle M. LaPak, Xiangnan Guan
Figure S1. Activation of p38 is not observed in CDK4/6i fibroblasts. Figure S2. The response of melanoma cells to co-culture conditioned media is genotype dependent. Figure S3. Senescent fibroblasts promote the growth of B16-F1 melanomas. Figure S4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d0515338c9391f8a97b854884ca487
https://doi.org/10.1158/1541-7786.22511587
https://doi.org/10.1158/1541-7786.22511587