Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Xiangmeng WANG"'
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 271, Iss , Pp 115966- (2024)
Aluminum (Al) is a common neurotoxicant in the environment, but the molecular mechanism of its toxic effects is still unclear. Studies have shown that aluminum exposure causes an increase in neuronal apoptosis. The aim of this study was to investigat
Externí odkaz:
https://doaj.org/article/eef75389f26d47f4a73cd6f1da0ed193
Publikováno v:
Zhongguo shuxue zazhi, Vol 35, Iss 8, Pp 810-813 (2022)
Hemoglobin-based oxygen carriers(HBOCs) is a category of artificial blood substitute with efficient oxygen carrying and delivery functions. Due to the outstanding oxygen-carrying properties of HBOCs, the studies of expanding its clinical applications
Externí odkaz:
https://doaj.org/article/e268787e37994943aa263f8f530bb844
Autor:
Bing Z. Carter, Po Yee Mak, Hong Mu, Xiangmeng Wang, Wenjing Tao, Duncan H. Mak, Elisha J. Dettman, Michael Cardone, Oleg Zernovak, Takahiko Seki, Michael Andreeff
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Although highly effective, BCR-ABL1 tyrosine kinase inhibitors do not target chronic myeloid leukemia (CML) stem cells. Most patients relapse upon tyrosine kinase inhibitor therapy cessation. We reported previously that combined BCR-ABL1 and BCL-2 in
Externí odkaz:
https://doaj.org/article/0f39552a7a3c496389d9f574bb13f752
Publikováno v:
Neurocomputing. 529:128-139
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9d612732d4545ecaf5445eac67031ff
https://doi.org/10.1016/j.neucom.2023.01.089
https://doi.org/10.1016/j.neucom.2023.01.089
Autor:
Michael Andreeff, Phuong K. Morrow, Xiaoyue Chen, Paul E. Hughes, Elias J. Jabbour, Marina Konopleva, Venkata L. Battula, Duncan H. Mak, Xiangmeng Wang, Vinitha M. Kuruvilla, Vivian Ruvolo, Qi Zhang, Wenjing Tao, Po Yee Mak, Bing Z. Carter
MCL-1 is known to play a major role in resistance to BCL-2 inhibition, but the contribution of other BCL-2 family proteins has not been fully explored. We, here, demonstrate the ineffectiveness of MCL-1 inhibitor AMG176 in venetoclax-resistant, and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392313a08e17e9b157cafff9a72d8ade
https://doi.org/10.1158/1535-7163.c.6543211
https://doi.org/10.1158/1535-7163.c.6543211
Autor:
Michael Andreeff, Phuong K. Morrow, Xiaoyue Chen, Paul E. Hughes, Elias J. Jabbour, Marina Konopleva, Venkata L. Battula, Duncan H. Mak, Xiangmeng Wang, Vinitha M. Kuruvilla, Vivian Ruvolo, Qi Zhang, Wenjing Tao, Po Yee Mak, Bing Z. Carter
Supplementary Figure from Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic–Resistant AML and AML Stem Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b9df7bd881c979d213013aa6cf113b
https://doi.org/10.1158/1535-7163.22521877
https://doi.org/10.1158/1535-7163.22521877
Autor:
Michael Andreeff, Phuong K. Morrow, Xiaoyue Chen, Paul E. Hughes, Elias J. Jabbour, Marina Konopleva, Venkata L. Battula, Duncan H. Mak, Xiangmeng Wang, Vinitha M. Kuruvilla, Vivian Ruvolo, Qi Zhang, Wenjing Tao, Po Yee Mak, Bing Z. Carter
Supplementary Data from Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic–Resistant AML and AML Stem Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e00ceef29bc70045cb13ccbe483b487
https://doi.org/10.1158/1535-7163.22521880.v1
https://doi.org/10.1158/1535-7163.22521880.v1
Autor:
Bing Z. Carter, Bing Xu, Michael Andreeff, David T. Weaver, Jonathan A. Pachter, Vivian Ruvolo, Ravikumar Visweswaran, Arvind Rao, Wenjing Tao, Hong Mu, Po Yee Mak, Xiangmeng Wang
Focal adhesion kinase (FAK) promotes cancer cell growth and metastasis. We previously reported that FAK inhibition by the selective inhibitor VS-4718 exerted antileukemia activities in acute myeloid leukemia (AML). The mechanisms involved, and whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0107b0df852ddc54270c2ae6596711c9
https://doi.org/10.1158/1535-7163.c.6543057
https://doi.org/10.1158/1535-7163.c.6543057
Autor:
Bing Z. Carter, Bing Xu, Michael Andreeff, David T. Weaver, Jonathan A. Pachter, Vivian Ruvolo, Ravikumar Visweswaran, Arvind Rao, Wenjing Tao, Hong Mu, Po Yee Mak, Xiangmeng Wang
Supplemental Table 1. Characteristics of AML patient samples used for the study. Supplemental Figure 1. PDX cells (mixed cells of the bone marrow and spleen), cultured alone or co-cultured with MSCs, were treated with VS-4718, ABT-199, or both. Annex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276ed583eff20f325ce9b479d9f0feb4
https://doi.org/10.1158/1535-7163.22521543.v1
https://doi.org/10.1158/1535-7163.22521543.v1
Autor:
Michael Andreeff, Steven Kornblau, Jonathan A. Pachter, David T. Weaver, Brittany Ragon, Nianxiang Zhang, Kevin Coombes, Yihua Qiu, Vivian R. Ruvolo, Hong Mu, Duncan H. Mak, Guillermo Garcia-Manero, Hui Yang, Xiangmeng Wang, Po Yee Mak, Bing Z. Carter
Supplementary Fig. S1. The chemical structure of VS-4718.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f21dbb98d673062e9ae981547afe206
https://doi.org/10.1158/1535-7163.22503348
https://doi.org/10.1158/1535-7163.22503348