Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Xianglei He"'
Autor:
Mengjia Lin, Xiaoyun Zheng, Jianing Yan, Fei Huang, Yilin Chen, Ran Ding, Jinkai Wan, Lei Zhang, Chenliang Wang, Jinchang Pan, Xiaolei Cao, Kaiyi Fu, Yan Lou, Xin-Hua Feng, Junfang Ji, Bin Zhao, Fei Lan, Li Shen, Xianglei He, Yunqing Qiu, Jianping Jin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract RNF214 is an understudied ubiquitin ligase with little knowledge of its biological functions or protein substrates. Here we show that the TEAD transcription factors in the Hippo pathway are substrates of RNF214. RNF214 induces non-proteolyti
Externí odkaz:
https://doaj.org/article/214141194198442996d29f4941f0603c
Autor:
Jianjuan Zhang, Fubo Ji, Yaqi Tan, Lei Zhao, Yongzhi Zhao, Jiaxin Liu, Liyuan Shao, Jiong Shi, Meihua Ye, Xianglei He, Jianping Jin, Bin Zhao, Jun Huang, Stephanie Roessler, Xin Zheng, Junfang Ji
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Intrahepatic cholangiocarcinoma (iCCA) is a highly lethal biliary epithelial cancer in the liver. Here, Laminin subunit gamma‐2 (LAMC2) with important oncogenic roles in iCCA is discovered. In a total of 231 cholangiocarcinoma patients (82
Externí odkaz:
https://doaj.org/article/93b88d3271324f46a375036d2ec012df
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Squamous cell carcinomas are the most common head and neck malignancies. Significant progress has been made in standard therapeutic methods combining surgery, radiation, and chemotherapy. Nevertheless, the 5-year survival rate remains at 40
Externí odkaz:
https://doaj.org/article/b423e4a4f4b947d49d814ba8ed93b56e
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Microsatellite instability (MSI) is one of the hallmarks of colorectal cancer (CRC). Mismatch repair (MMR) protein expression may reflect MSI status. To analyze the concordance between MSI and MMR expression in CRC and their clinicopathological chara
Externí odkaz:
https://doaj.org/article/683f5a8674e34795aa173353745f9329
Autor:
Hujuan Yang, Zhiquan Qin, Xianglei He, Qian Xue, Hongying Zhou, Jie Sun, Xiaoyi Li, Tongwei Zhao
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Undifferentiated pleomorphic sarcoma (UPS) is a rare and aggressive soft tissue tumor with a high degree of malignancy and rapid progression, usually occurring in the extremities, retroperitoneum, and abdomen, whereas it rarely arises in the mediasti
Externí odkaz:
https://doaj.org/article/01cd9572709742ee83fc373623c3e81b
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeTo investigate the clinicopathological characteristics, diagnosis and key points in the differential diagnosis of patients with gastric cancer (GC) with features of a submucosal tumour (GCSMT).MethodsThe clinical presentation and imaging findi
Externí odkaz:
https://doaj.org/article/d69fa3c07eab4f6b92f9fd5c79224e9d
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-21 (2022)
Abstract Background Inspired by nature, the biomimetic approach has been incorporated into drug nanocarriers for cancer targeted chemotherapy. The nanocarriers are cloaked in cell membranes, which enables them to incorporate the functions of natural
Externí odkaz:
https://doaj.org/article/895a7540255a4c25a7dae494c9041b7e
Autor:
Miaomiao Shen, Xiaona Yin, Yanfeng Bai, Huizhi Zhang, Guoqing Ru, Xianglei He, Xiaodong Teng, Guorong Chen, Ming Zhao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Papillary renal neoplasm with reverse polarity (PRNRP) is a recently described, rare renal tumor that differs clinically, morphologically, and molecularly from papillary renal cell carcinoma (RCC). To further characterize the pathological spectrum of
Externí odkaz:
https://doaj.org/article/979d9dc2d7154b399214f0bc527adbb9
Autor:
Zhaoqiang Jiang, Wei Shen, Shibo Ying, Zhibin Gao, Xianglei He, Riping Chen, Hailing Xia, Xinnian Guo, Yuan Fang, Yixiao Zhang, Jianjiang Miao, Jian Zhou, Xing Zhang, Junqiang Chen, Jianlin Lou
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Fibulin-3 is an extracellular matrix glycoprotein widely expressed in various tissues. Tissue fibulin-3 expression have never been reported in association with prognosis of mesothelioma. Hence, we sought to determine the association between
Externí odkaz:
https://doaj.org/article/581dcb45178e4732b0734e5acddf5304
Publikováno v:
Mathematical Biosciences and Engineering, Vol 17, Iss 4, Pp 3252-3259 (2020)
To investigate the significance of lymph node micrometastasis in T1N0 early gastric cancer. Lymph node micrometastasis may be a key mechanism in the recurrent T1N0 EGC patients after surgical treatment. It’s unknow whether it is safe to leave the l
Externí odkaz:
https://doaj.org/article/12f35fdbe004435aa078f16f846b80a9