Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Xiangju Wang"'
Autor:
Xiangju Wang, Chang Seong Kim, Benjamin C. Adams, Ray Wilkinson, Michelle M. Hill, Alok K. Shah, Ahmed Mohamed, Mriga Dutt, Monica S.Y. Ng, Jacobus P.J. Ungerer, Helen G. Healy, Andrew J. Kassianos
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103042- (2024)
Hypoxia is the key pathobiological trigger of tubular oxidative stress and cell death that drives the transition of acute kidney injury (AKI) to chronic kidney disease (CKD). The mitochondrial-rich proximal tubular epithelial cells (PTEC) are uniquel
Externí odkaz:
https://doaj.org/article/898c2efbe8a34d2eb160c44c13860921
Autor:
Kurt T. K. Giuliani, Anca Grivei, Purba Nag, Xiangju Wang, Melissa Rist, Katrina Kildey, Becker Law, Monica S. Ng, Ray Wilkinson, Jacobus Ungerer, Josephine M. Forbes, Helen Healy, Andrew J. Kassianos
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-13 (2022)
Abstract Inflammasomes are multiprotein platforms responsible for the release of pro-inflammatory cytokines interleukin (IL)-1β and IL-18. Mouse studies have identified inflammasome activation within dendritic cells (DC) as pivotal for driving tubul
Externí odkaz:
https://doaj.org/article/3f6627c645814f06a5a8676f3b366cb9
Autor:
Muhammad Ali Khan, Purba Nag, Anca Grivei, Kurt T. K. Giuliani, Xiangju Wang, Vishal Diwan, Wendy Hoy, Helen Healy, Glenda Gobe, Andrew J. Kassianos
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-12 (2022)
Externí odkaz:
https://doaj.org/article/f82ab151dced496797be4d83e6b73a17
Autor:
Xiangju Wang, Ray Wilkinson, Katrina Kildey, Jacobus P. J. Ungerer, Michelle M. Hill, Alok K. Shah, Ahmed Mohamed, Mriga Dutt, Jeffrey Molendijk, Helen Healy, Andrew J. Kassianos
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 4, Pp n/a-n/a (2021)
Abstract Proximal tubular epithelial cells (PTEC) are central players in inflammatory kidney diseases. However, the complex signalling mechanism/s via which polarized PTEC mediate disease progression are poorly understood. Small extracellular vesicle
Externí odkaz:
https://doaj.org/article/362686f92a7b4321ab77cd8a5c3ee295
Autor:
Katrina Kildey, Ross S. Francis, Sebastian Hultin, Michelle Harfield, Kurt Giuliani, Becker M. P. Law, Xiangju Wang, Emily J. See, George John, Jacobus Ungerer, Ray Wilkinson, Andrew J. Kassianos, Helen Healy
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Human natural killer (NK) cells are key functional players in kidney transplant rejection. However, the respective contributions of the two functionally distinct human NK cell subsets (CD56bright cytokine-producing vs. CD56dim cytotoxic e
Externí odkaz:
https://doaj.org/article/d20211faf0f04c63aad11cdff41ffb57
Autor:
Xiangju Wang, Ray Wilkinson, Katrina Kildey, Jeremy Potriquet, Jason Mulvenna, Richard J. Lobb, Andreas Möller, Nicole Cloonan, Pamela Mukhopadhyay, Andrew J. Kassianos, Helen Healy
Publikováno v:
Journal of Extracellular Vesicles, Vol 6, Iss 1 (2017)
Human proximal tubular epithelial cells (PTEC) of the kidney are known to respond to and mediate the disease process in a wide range of kidney diseases, yet their exosomal production and exosome molecular cargo remain a mystery. Here we investigate,
Externí odkaz:
https://doaj.org/article/4fa2d015c4ba42aea975120cb4604e2b
Autor:
Sandeep Sampangi, Andrew J Kassianos, Xiangju Wang, Kenneth W Beagley, Travis Klein, Sadia Afrin, Helen Healy, Ray Wilkinson
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134688 (2015)
Proximal tubule epithelial cells (PTEC) of the kidney line the proximal tubule downstream of the glomerulus and play a major role in the re-absorption of small molecular weight proteins that may pass through the glomerular filtration process. In the
Externí odkaz:
https://doaj.org/article/8ce69e093c894a93984f501f6a62b0fa
Autor:
Ray Wilkinson, Xiangju Wang, Andrew J Kassianos, Steven Zuryn, Kathrein E Roper, Andrew Osborne, Sandeep Sampangi, Leo Francis, Vishwas Raghunath, Helen Healy
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87345 (2014)
Interstitial fibrosis, a histological process common to many kidney diseases, is the precursor state to end stage kidney disease, a devastating and costly outcome for the patient and the health system. Fibrosis is historically associated with chronic
Externí odkaz:
https://doaj.org/article/9841129d5b174259b8ad15be40b12cd1
Autor:
Khan, Muhammad Ali1,2,3,4,5,6 Muhammad.A.Khan@uq.edu.au, Xiangju Wang3,4 Xiangju.Wang@qimrberghofer.edu.au, Giuliani, Kurt T. K.2,3,4 Kurt.Giuliani@uqconnect.edu.au, Nag, Purba3,4 Purba.Nag@qimrberghofer.edu.au, Grivei, Anca3,4 Anca.Grivei@qimrberghofer.edu.au, Ungerer, Jacobus2,3 W.Hoy@uq.edu.au, Hoy, Wendy1,7 Helen.Healy@health.qld.gov.au, Healy, Helen1,3,4,7 G.Gobe@uq.edu.au, Gobe, Glenda1,2,5,7 Andrew.Kassianos@qimrberghofer.edu.au, Kassianos, Andrew J.3,4,7
Publikováno v:
International Journal of Molecular Sciences. 1/15/2020, Vol. 21 Issue 2, p1-15. 15p. 1 Chart, 6 Graphs.
Autor:
Anca Grivei, Xiangju Wang, Kurt T. K. Giuliani, Pedro F. H. Gois, Kirsten Hepburn, George John, Jacobus P.J. Ungerer, Helen Healy, L. Francis, Andrew J. Kassianos
Publikováno v:
Free Radical Biology and Medicine. 160:690-695
Acute kidney injury (AKI) is a life-threatening complication of rhabdomyolysis. The pathophysiological mechanisms of rhabdomyolysis-induced AKI (RIAKI) have been extensively studied in the murine system, yet clinical translation of this knowledge to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fa5e27459533aaa6f6cef2a4a539a0
https://doi.org/10.1016/j.freeradbiomed.2020.09.011
https://doi.org/10.1016/j.freeradbiomed.2020.09.011