Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Xiangguo Qi"'
Publikováno v:
Acta Oto-Laryngologica. 140:501-508
Background: The auditory and speech development of the children with cochlear implants (CIs) are influenced by many factors.Objective: To study the developmental trajectory and influencing factors ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f00aee8152096de8996155b595d985
https://doi.org/10.1080/00016489.2020.1736622
https://doi.org/10.1080/00016489.2020.1736622
Autor:
Laura P. van Lieshout, Amira D. Rghei, Wenguang Cao, Shihua He, Geoff Soule, Wenjun Zhu, Sylvia P. Thomas, Debra Sorensen, Kathy Frost, Kevin Tierney, Brad Thompson, Stephanie Booth, David Safronetz, Raveendra R. Kulkarni, Byram W. Bridle, Xiangguo Qiu, Logan Banadyga, Sarah K. Wootton
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 505-518 (2022)
Filoviruses cause severe hemorrhagic fever with case fatality rates as high as 90%. Filovirus-specific monoclonal antibodies (mAbs) confer protection in nonhuman primates as late as 5 days after challenge, and FDA-approved mAbs REGN-EB3 and mAb114 ha
Externí odkaz:
https://doaj.org/article/50cc389f7095494bba9d58a113335768
Autor:
Guillaume Poliquin, Duane Funk, Shane Jones, Kaylie Tran, Charlene Ranadheera, Mable Hagan, Kevin Tierney, Allen Grolla, Amrinder Dhaliwal, Alexander Bello, Anders Leung, Cory Nakamura, Darwyn Kobasa, Darryl Falzarano, Lauren Garnett, Hugues Fausther Bovendo, Heinz Feldmann, Murray Kesselman, Gregory Hansen, Jason Gren, George Risi, Mia Biondi, Todd Mortimer, Trina Racine, Yvon Deschambault, Sam Aminian, Jocelyn Edmonds, Ray Sourette, Mark Allan, Lauren Rondeau, Sharron Hadder, Christy Press, Christine DeGraff, Stephanie Kucas, Bradley W. M. Cook, B. J. Hancock, Anand Kumar, Reeni Soni, Darryl Schantz, Jarrid McKitrick, Bryce Warner, Bryan D. Griffin, Xiangguo Qiu, Gary P. Kobinger, Dave Safronetz, Derek Stein, Todd Cutts, James Kenny, Geoff Soule, Robert Kozak, Steven Theriault, Liam Menec, Robert Vendramelli, Sean Higgins, Guodong Liu, Niaz Md Rahim, Samantha Kasloff, Angela Sloan, Shihua He, Nikesh Tailor, Michael Gray, James E. Strong
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background There are currently limited data for the use of specific antiviral therapies for the treatment of Ebola virus disease (EVD). While there is anecdotal evidence that supportive care may be effective, there is a paucity of direct exp
Externí odkaz:
https://doaj.org/article/877aaa5f56994221966d8a8be6302d4a
Publikováno v:
Biosafety and Health, Vol 1, Iss 1, Pp 6-13 (2019)
The development of monoclonal antibodies to treat disease caused by filoviruses, particularly Ebola virus, has risen steeply in recent years thanks to several key studies demonstrating their remarkable therapeutic potential. The increased drive to de
Externí odkaz:
https://doaj.org/article/ba76ee318cc04e5dbdf2d1c647b4f17f
Autor:
William J. Liu, Weifeng Shi, Wuyang Zhu, Cong Jin, Shumei Zou, Ji Wang, Yuehua Ke, Xiaofeng Li, Mi Liu, Tao Hu, Hang Fan, Yigang Tong, Xiang Zhao, Wenbin Chen, Yuhui Zhao, Di Liu, Gary Wong, Chengchao Chen, Chunyu Geng, Weiwei Xie, Hui Jiang, Idrissa Laybor Kamara, Abdul Kamara, Matt Lebby, Brima Kargbo, Xiangguo Qiu, Yu Wang, Xiaofeng Liang, Mifang Liang, Xiaoping Dong, Guizhen Wu, George F. Gao, Yuelong Shu
Publikováno v:
Biosafety and Health, Vol 1, Iss 1, Pp 14-24 (2019)
The onsite next generation sequencing (NGS) of Ebola virus (EBOV) genomes during the 2013–2016 Ebola epidemic in Western Africa provides an opportunity to trace the origin, transmission, and evolution of this virus. Herein, we have diagnosed a coho
Externí odkaz:
https://doaj.org/article/6daadf533e41410cb4f1a39465fe02b7
Publikováno v:
Virology Journal, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background HIV integrase (IN) and its cellular cofactors, including lens-epithelium-derived growth factor (LEDGF/p75), Ku70, p300, and Rad52, are subject to small ubiquitin-like modifier (SUMO) modification. In addition to covalent SUMOylati
Externí odkaz:
https://doaj.org/article/abe7d5312ff6450985fbffd68e5fb725
Autor:
Jennifer M. Brannan, Shihua He, Katie A. Howell, Laura I. Prugar, Wenjun Zhu, Hong Vu, Sergey Shulenin, Shweta Kailasan, Henna Raina, Gary Wong, Md Niaz Rahim, Logan Banadyga, Kevin Tierney, Xuelian Zhao, Yuxing Li, Frederick W. Holtsberg, John M. Dye, Xiangguo Qiu, M. Javad Aman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV). Here, authors develop cocktails of mAbs that protect nonhuman primates against EBOV, SU
Externí odkaz:
https://doaj.org/article/b99aa7a0e5ce4018ab41eac4e31287f3
Autor:
Logan Banadyga, Wenjun Zhu, Shweta Kailasan, Katie A. Howell, Krzysztof Franaszek, Shihua He, Vinayakumar Siragam, Keding Cheng, Feihu Yan, Estella Moffat, Wenguang Cao, Anders Leung, Carissa Embury-Hyatt, M. Javad Aman, Xiangguo Qiu
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Ebola virus remains a global threat to public health and biosecurity, yet we still know relatively little about its pathogenesis and the complications that arise following recovery. With nearly 20,000 survivors from the 2013–2016 West African outbr
Externí odkaz:
https://doaj.org/article/909040b19d774466a013d0a904fb9c04
Autor:
Haley L DeMers, Shihua He, Sujata G Pandit, Emily E Hannah, Zirui Zhang, Feihu Yan, Heather R Green, Denise F Reyes, Derrick Hau, Megan E McLarty, Louis Altamura, Cheryl Taylor-Howell, Marcellene A Gates-Hollingsworth, Xiangguo Qiu, David P AuCoin
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 11, p e0008817 (2020)
The 2013-2016 Ebola virus (EBOV) outbreak in West Africa and the ongoing cases in the Democratic Republic of the Congo have spurred development of a number of medical countermeasures, including rapid Ebola diagnostic tests. The likelihood of transmis
Externí odkaz:
https://doaj.org/article/1376dbcc49d2491e9ab334f9ee9fdbe4
Autor:
Pengfei Fan, Xiangyang Chi, Guodong Liu, Guanying Zhang, Zhengshan Chen, Yujiao Liu, Ting Fang, Jianmin Li, Logan Banadyga, Shihua He, Changming Yu, Xiangguo Qiu, Wei Chen
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Ebola virus (EBOV) can cause severe hemorrhagic fever in humans, and no approved treatment is currently available. Although several antibodies have achieved good protection in animal models, the potential emerging isolates of ebolavirus and the unkno
Externí odkaz:
https://doaj.org/article/1ff2ac0787694dc58c1932b5e05d7ebd