Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Xiangguo, Meng"'
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
In this study, the absorption, distribution, metabolism and excretion (ADME) of sodium danshensu (Sodium DL-β-(3, 4-dihydroxyphenyl)lactate), one of the main water-soluble active constituents in Salvia miltiorrhiza, were evaluated in rats. Pharmacok
Externí odkaz:
https://doaj.org/article/6636d8c2632c462f9ff02bb261f9a8cd
Publikováno v:
International Journal of Theoretical Physics. 61
Publikováno v:
2022 IEEE 10th Asia-Pacific Conference on Antennas and Propagation (APCAP).
Autor:
Jing-Gen Liu, Xiangguo Meng, Jing Liu, Wenli Wang, Huoming Huang, Jing-Rui Chai, Jing Chen, Wei Li, Xue-Ping Li, Congmin Yuan, Wei Fu, Xinwei Li, Xue-Jun Xu, Peng Xie, Yujun Wang, Yuanyuan Qian
Publikováno v:
Journal of Medicinal Chemistry. 64:9458-9483
Management of moderate to severe pain relies heavily on opioid analgesics such as morphine, oxycodone, and fentanyl in clinics. However, their prolonged use was associated with undesirable side effects. Many new strategies to reduce side effects have
Autor:
Xiangguo Meng, Siju Bi, Shixin Jin, Kai Wu, Shanchao Wu, Lei Shao, Pierre-Antoine Bonnet, Chunquan Sheng
Publikováno v:
Chinese Chemical Letters. 34:108096
Publikováno v:
Evidence-based complementary and alternative medicine : eCAM. 2022
Type 2 diabetes mellitus (T2DM) has been regarded as a critical risk factor for pulmonary tuberculosis (PTB). Ginsenoside Rg1 has been identified as a potential therapeutic agent for T2DM by suppressing the inflammatory response. However, the effect
Publikováno v:
2022 China Semiconductor Technology International Conference (CSTIC).
Publikováno v:
Catalysis Science & Technology. 10:1650-1660
Steric hindrance in the binding pocket of an alcohol dehydrogenase (ADH) has a great impact on its activity and stereoselectivity simultaneously. Due to the subtle structural difference between two bulky phenyl substituents, the asymmetric synthesis
Publikováno v:
Bioorganic chemistry. 122
On the basis of synergistic effect between topoisomerase (Top) and histone deacetylase (HDAC) inhibitors, a series of novel evodiamine-based Top/HDAC dual inhibitors were designed and synthesized. Systematic structure-activity relationship (SAR) stud
Publikováno v:
Applied Microbiology and Biotechnology. 103:4417-4427
(2R,3S)-N-tert-Butoxycarbonyl-3-amino-1-chloro-2-hydroxy-4-phenylbutane (1b) is key for the synthesis of the antiviral drug atazanavir. It can be obtained via the stereoselective bioreduction of (3S)-3-(N-Boc-amino)-1-chloro-4-phenyl-butanone (1a) wi