Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Xiangde, Zhao"'
Autor:
Hongyi Zhou, Ziang Xie, Yu Qian, Weiyu Ni, Lei Cui, Xiangqian Fang, Shuanglin Wan, Xiangde Zhao, An Qin, Shunwu Fan, Yizheng Wu
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 10, Pp 2283-2295 (2024)
Abstract N6-methyladenosine (m6A) modification is one of the most prevalent forms of epigenetic modification and plays an important role in the development of degenerative diseases such as osteoarthritis (OA). However, the evidence concerning the rol
Externí odkaz:
https://doaj.org/article/4c577424afc64586869ae5acc3995191
Autor:
Hong Xue, Zhenhua Feng, Putao Yuan, Li Qiao, Qiliang Lou, Xiangde Zhao, Qingliang Ma, Shiyu Wang, Yang Shen, Huali Ye, Jiao Cheng, Jiying Wang, Shuanglin Wan, Boya Zhang, Peihua Shi, Xuewu Sun
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Bone and mineral metabolism homeostasis accounts for the maintenance of normal skeletal remodeling. However, with aging and changes in hormone levels, over-activated osteoclasts disrupt homeostasis, induce osteoporosis, and even cause osteop
Externí odkaz:
https://doaj.org/article/f2970c58a18b48229aaf53d433d160e5
Autor:
Hong Xue, Zhenhua Feng, Putao Yuan, Li Qiao, Qiliang Lou, Xiangde Zhao, Qingliang Ma, Shiyu Wang, Yang Shen, Huali Ye, Jiao Cheng, Jiying Wang, Shuanglin Wan, Boya Zhang, Peihua Shi, Xuewu Sun
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/37fd9436e9fb42e1bb973b0b40361b4f
Autor:
Ziang Xie, Lei Hou, Shuying Shen, Yizheng Wu, Jian Wang, Zhiwei Jie, Xiangde Zhao, Xiang Li, Xuyang Zhang, Junxin Chen, Wenbin Xu, Lei Ning, Qingliang Ma, Shiyu Wang, Haoming Wang, Putao Yuan, Xiangqian Fang, An Qin, Shunwu Fan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Mechanical force is critical for the development and remodeling of bones. Here the authors report that mechanical force regulates the production of the metabolite asymmetric dimethylarginine via regulating the expression of the hydrolytic enzyme dime
Externí odkaz:
https://doaj.org/article/de35a50f762c45b28e46ba6913cdceeb
Autor:
Zhiwei Jie, Shiyu Wang, Qingliang Ma, Yang Shen, Xiangde Zhao, Hejun Yu, Ziang Xie, Chao Jiang
Publikováno v:
Journal of Bone Oncology, Vol 35, Iss , Pp 100439- (2022)
Breast cancer metastases to the bone can lead to a series of bone-related events that seriously affect the quality of life. Pexmetinib, a novel p38 mitogen-activated protein kinase (p38) inhibitor that has been evaluated in phase I clinical trials fo
Externí odkaz:
https://doaj.org/article/6c9f85baa97c459db52e0afa520c1c95
Autor:
Xiang Li, Lei Ning, Jianjun Ma, Ziang Xie, Xiangde Zhao, Gangliang Wang, Xinyu Wan, Pengcheng Qiu, Teng Yao, Haoming Wang, Shunwu Fan, Shuanglin Wan
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-21 (2019)
Abstract Background Osteoclasts are key determinant cellular components implicated in the development and progression of disorders driven by bone damage. Herein, we studied the upshot of T007, an antagonist of peroxisome proliferator-activated recept
Externí odkaz:
https://doaj.org/article/f9d19aa8b3a249ad984b0dda67822d0f
Autor:
Xuewu Sun, Ziang Xie, Bin Hu, Boya Zhang, Yan Ma, Xin Pan, Hai Huang, Jiying Wang, Xiangde Zhao, Zhiwei Jie, Peihua Shi, Zhijun Chen
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
The dysregulation of ROS production and osteoclastogenesis is involved in the progress of osteoporosis. To identify novel and effective targets to treat this disease, it is important to explore the underlying mechanisms. In our study, we firstly test
Externí odkaz:
https://doaj.org/article/c755db587a6e4802abda0fd74faddf9c
Autor:
Bao Huang, Jiasheng Wang, Xuyang Zhang, Ziang Xie, Hao Wu, Junhui Liu, Zhiwei Jie, Xiangde Zhao, An Qin, Shunwu Fan, Jian Chen, Fengdong Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Activation of osteoclast formation and function is crucial for the development of osteolytic diseases such as osteoporosis. RANKL (receptor activator of nuclear factor-κB ligand) activates NF-κB (nuclear factor κB), MAPK (mitogen-activated protein
Externí odkaz:
https://doaj.org/article/0ba521d21bd24cc585c3ffc2d3c2be67
Autor:
Putao, Yuan, Zhenhua, Feng, Hai, Huang, Gangliang, Wang, Zhijun, Chen, Guang, Xu, Ziang, Xie, Zhiwei, Jie, Xiangde, Zhao, Qingliang, Ma, Shiyu, Wang, Yang, Shen, Yizhen, Huang, Ying, Han, Huali, Ye, Jiying, Wang, Peihua, Shi, Xuewu, Sun
Publikováno v:
International Journal of Biological Sciences. 18:3122-3136
Mutations and altered expression of deubiquitinating enzymes (DUBs) profoundly influence tumor progression. Ubiquitin-specific protease 1 (USP1) is a well-characterized human DUB reportedly overexpressed in and associated with maintaining the mesench
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a903f4818a148020343824a3224d33
https://doi.org/10.7150/ijbs.65428
https://doi.org/10.7150/ijbs.65428
Autor:
Hong Xue, Zhenhua Feng, Putao Yuan, Li Qiao, Qiliang Lou, Xiangde Zhao, Qingliang Ma, Shiyu Wang, Huali Ye, Jiao Cheng, Jiying Wang, Peihua Shi, Xuewu Sun
Background and Purpose: Overactivated osteoclasts disrupt the mineral homeostasis of bone, inducing osteoporosis. Despite the rapid development of pharmacological therapy in osteoporosis, a safer and more effective treatment remains to be explored. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f70781d214360dc0c99e41dfb1d7bca
https://doi.org/10.22541/au.167749195.50259925/v1
https://doi.org/10.22541/au.167749195.50259925/v1
