Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Xiangcheng, Zhu"'
Autor:
Zhoukang Zhuang, Wenping Kong, Zhongqing Wen, Nian Tong, Jing Lin, Fan Zhang, Zhiying Fan, Liwei Yi, Yong Huang, Yanwen Duan, Xiaohui Yan, Xiangcheng Zhu
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Anthraquinone-fused enediynes (AFEs) are excellent payloads for antibody-drug conjugates (ADCs). The yields of AFEs in the original bacterial hosts are extremely low. Multiple traditional methods had been adopted to enhance the pr
Externí odkaz:
https://doaj.org/article/f308de08a1c74e6889ca58ff96e8b3c3
Publikováno v:
Bioengineering, Vol 11, Iss 11, p 1128 (2024)
Strain robustness and titer improvement are major challenges faced in the industrial development of natural products from Streptomyces. Tiancimycins (TNMs) produced by Streptomyces sp. CB03234 are promising anticancer payloads for antibody-drug conju
Externí odkaz:
https://doaj.org/article/583b52dd607d4da78e15e5683788e231
Publikováno v:
Advanced Science, Vol 11, Iss 17, Pp n/a-n/a (2024)
Abstract Although natural products are essential sources of small‐molecule antitumor drugs, some can exert substantial toxicities, limiting their clinical utility. Anthraquinone‐fused enediyne natural products are remarkably potent antitumor drug
Externí odkaz:
https://doaj.org/article/7e9737916a6447819e52c1898529a284
Publikováno v:
Engineering Microbiology, Vol 4, Iss 1, Pp 100121- (2024)
Natural product biosynthesis is controlled at multiple levels. Characterization of naturally occurring promoters has facilitated the study of the synthetic biology of natural products. Herein, we report the discovery of two high-yield actinomycin D (
Externí odkaz:
https://doaj.org/article/451d1e66a2334110a974bca3b7a10d59
Publikováno v:
Molecules, Vol 29, Iss 9, p 1982 (2024)
Chalkophomycin is a novel chalkophore with antibiotic activities isolated from Streptomyces sp. CB00271, while its potential in studying cellular copper homeostasis makes it an important probe and drug lead. The constellation of N-hydroxylpyrrole, 2H
Externí odkaz:
https://doaj.org/article/9e65d3718a2b4c51818d8d446537ab2a
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-11 (2022)
Abstract Background The anthraquinone-fused 10-membered enediynes (AFEs), represented by tiancimycins (TNMs), possess a unique structural feature and promising potentials as payloads of antitumor antibody–drug conjugates. Despite many efforts, the
Externí odkaz:
https://doaj.org/article/db7d1f6315854f2f9f6d70f86b72a230
Autor:
Xiangcheng Zhu, Jin Chen, Shan Huang, Weiwei Li, Josep Penuelas, Ji Chen, Feng Zhou, Weijian Zhang, Ganghua Li, Zhenghui Liu, Yanfeng Ding, Songhan Wang, Kees Jan van Groenigen, Yu Jiang
Publikováno v:
Communications Earth & Environment, Vol 3, Iss 1, Pp 1-9 (2022)
Heat resilience and tolerance of rice crops is enhanced by manure amendment and could improve yield stability under projected climate change, suggest a meta-analysis and long term manure amendment experiments.
Externí odkaz:
https://doaj.org/article/9d40a7daa5c4486ca38efff236614fda
Autor:
Jingyan Zhang, Ying Sun, Yeji Wang, Xin Chen, Lu Xue, Jingjing Zhang, Xiangcheng Zhu, Yanwen Duan, Xiaohui Yan
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-14 (2021)
Abstract Background Rubiginones belong to the angucycline family of aromatic polyketides, and they have been shown to potentiate the vincristine (VCR)-induced cytotoxicity against VCR-resistant cancer cell lines. However, the biosynthetic gene cluste
Externí odkaz:
https://doaj.org/article/a4070d37d1fe4763b9807488c45bb034
Autor:
Jin Chen, Xiangcheng Zhu, Jiang Xie, Guoqiang Deng, Tianhua Tu, Xianjiao Guan, Zhen Yang, Shan Huang, Xianmao Chen, Caifei Qiu, Yinfei Qian, Caihong Shao, Minggang Xu, Chunrui Peng
Publikováno v:
Crop Journal, Vol 9, Iss 4, Pp 805-815 (2021)
Rational nitrogen (N) application can greatly increase rice (Oryza sativa L.) yield. However, excessive N input can lead not only to low N use efficiency (NUE) but also to severe environmental pollution. Reducing N application rate with a higher plan
Externí odkaz:
https://doaj.org/article/e9f3712bb1e94caaae0cf5419f2b7c86
Autor:
Wenping Kong, Chengshuang Huang, Jie Shi, Yu Li, Xinxin Jiang, Quwen Duan, Yong Huang, Yanwen Duan, Xiangcheng Zhu
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-11 (2019)
Abstract Background The global prevalence of traditional Chinese medicine stimulates the prosperous development of herb medicines, but the annual generation of massive herb residues becomes big issues about environmental pollution and waste of resour
Externí odkaz:
https://doaj.org/article/d473b64452a143b7aaa6cf553636b05b