Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Xiang-yao Li"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract The anterior cingulate cortex (ACC) is one of the critical brain areas for processing noxious information. Previous studies showed that peripheral nerve injury induced broad changes in the ACC, contributing to pain hypersensitivity. The neur
Externí odkaz:
https://doaj.org/article/4e66636f657644b996c01316a24e0075
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
IntroductionThe cingulate cortex, with its subregions ACC, MCC, and RSC, is key in pain processing. However, the detailed interactions among these regions in modulating pain sensation have remained unclear.MethodsIn this study, chemogenetic tools wer
Externí odkaz:
https://doaj.org/article/d21e8a15c0f64003b78ecebb50f968a5
Autor:
Jing-Hua Wang, Cheng Wu, Yan-Na Lian, Xiao-Wen Cao, Zi-Yue Wang, Jia-Jun Dong, Qin Wu, Li Liu, Li Sun, Wei Chen, Wen-Juan Chen, Zhi Zhang, Min Zhuo, Xiang-Yao Li
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113551- (2023)
Summary: The retrosplenial cortex (RSC) is a vital area for storing remote memory and has recently been found to undergo broad changes after peripheral nerve injury. However, little is known about the role of RSC in pain regulation. Here, we examine
Externí odkaz:
https://doaj.org/article/931ec1941e5c4391bb5e6658862919dc
Autor:
Cheng Wu, Hui-Fang Shang, Yong-Jie Wang, Jing-Hua Wang, Zhen-Xing Zuo, Yan-Na Lian, Li Liu, Chen Zhang, Xiang-Yao Li
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The deficit of fragile X messenger ribonucleoprotein (FMRP) leads to intellectual disability in human and animal models, which also leads to desensitization of pain after nerve injury. Recently, it was shown that the protein arginine methyltransferas
Externí odkaz:
https://doaj.org/article/990c1a0a78a94fc994d25a549b443ae3
Autor:
Li Sun, Rui Liu, Fang Guo, Man-qing Wen, Xiao-lin Ma, Kai-yuan Li, Hao Sun, Ceng-lin Xu, Yuan-yuan Li, Meng-yin Wu, Zheng-gang Zhu, Xin-jian Li, Yan-qin Yu, Zhong Chen, Xiang-yao Li, Shumin Duan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
The parabrachial nucleus (PBN) projects to the amygdala, and contributes to affective aspects of neuropathic pain. Here the authors demonstrate that the lateral parabrachial nucleus (LPBN) contributes to hypersensitivity in a mouse model of neuropath
Externí odkaz:
https://doaj.org/article/ca966f8a0369483dafb67a92447ca6e3
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
The cerebellum is conceptualized as a processor of complex movements. Many diseases with gene-targeted mutations, including Fahr’s disease associated with the loss-of-function mutation of meningioma expressed antigen 6 (Mea6), exhibit cerebellar ma
Externí odkaz:
https://doaj.org/article/f21e5f5cbdf941398c69b81b3be9d33a
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Neuropathic pain (NP) is an intractable disease accompanying with allodynia, hyperalgesia and spontaneous pain. Accumulating evidence suggested that large volume of neurotransmitters, genes, and signaling pathways were implicated with the initiation
Externí odkaz:
https://doaj.org/article/e9f4b26acb1049df98376b255b69efc7
Autor:
Yonglu Tian, Chaojuan Yang, Yaxuan Cui, Feng Su, Yongjie Wang, Yangzhen Wang, Peijiang Yuan, Shujiang Shang, Hao Li, Jizong Zhao, Desheng Zhu, Shiming Tang, Peng Cao, Yunbo Liu, Xunli Wang, Liecheng Wang, Wenbo Zeng, Haifei Jiang, Fei Zhao, Minhua Luo, Wei Xiong, Zilong Qiu, Xiang-Yao Li, Chen Zhang
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1734-1744 (2018)
Summary: Short-term memory (STM) is crucial for animals to hold information for a small period of time. Persistent or recurrent neural activity, together with neural oscillations, is known to encode the STM at the cellular level. However, the coding
Externí odkaz:
https://doaj.org/article/8461fa37dd394514890d9aaed7047bc5
Autor:
Juan Yang, Fei Yuan, Gang Ye, Yong-Jie Wang, Cheng Wu, Jinghua Wang, Xiang-Yao Li, Zhiying Feng
Publikováno v:
Pain Research and Management, Vol 2019 (2019)
Background. Surgery is a frequent cause of persistent pain. Unrelieved chronic postsurgical pain causes unnecessary patient suffering and discomfort and usually leads to psychological complications. The rat model of skin/muscle incision and retractio
Externí odkaz:
https://doaj.org/article/f1b7c275cbbb4873991e7b6d32d85e16
Autor:
Ya-Jun Xie, Lin Zhou, Yin Wang, Nan-Wei Jiang, Shenglong Cao, Chong-Yu Shao, Xin-Tai Wang, Xiang-Yao Li, Ying Shen, Liang Zhou
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Leucine-rich glioma inactivated 1 (Lgi1), a putative tumor suppressor, is tightly associated with autosomal dominant lateral temporal lobe epilepsy (ADLTE). It has been shown that Lgi1 regulates the myelination of Schwann cells in the peripheral nerv
Externí odkaz:
https://doaj.org/article/b627b08acd2a4695b276f48ff6e7fc87