Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Xiang-Zheng Tang"'
Publikováno v:
Future Medicinal Chemistry. 13:601-612
Background: Quinazoline-based compounds have been proved effective in the treatment of cancers for years. Materials & methods: The structural features of several inhibitors of EGFR were integrated and quinazolines with a benzazepine moiety at the 4-p
Autor:
Ming Yan, Ri‐xing Chen, Lei Chen, Zhen-yu Chen, Hua-Ju Liang, Xue-jing Zhang, Xiang-Zheng Tang
Publikováno v:
Advanced Synthesis & Catalysis. 361:3324-3330
Autor:
Yamin Gao, Xiang-Zheng Tang, Yunxiang Tang, Ming Yan, Jie Liang, Tianyu Zhang, Cuiting Fang, Hua-Ju Liang
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:372-381
A series of meta-amido bromophenol derivatives were designed and synthesized. The compounds were found to potently inhibit the growth of Mycobacterium tuberculosis H37Ra. They also exhibited moderate inhibitory activity against Mycobacterium tubercul
Publikováno v:
Chinese Chemical Letters. 30:395-397
A facile synthesis of tetraarylpyrazoles has been developed via t- BuOK/DMF promoted intermolecular cycloaddition of hydrazones and 1,2-diarylalkynes. A possible reaction pathway via a hydrazone radical is proposed.
Autor:
Niu-niu Zhang, Xuan Yining, Shenquan Guo, Ming Yan, Xiang-Zheng Tang, Zhi-feng Mao, Xue-jing Zhang
Publikováno v:
Chinese Chemical Letters. 30:406-408
An efficient synthesis of β-alkoxycarbonyl vinylsulfonium salts had been developed. Their reaction with indene-1,3-diones and other active methylene compounds provided cyclopropane carboxylates in good yields. A tentative reaction mechanism was prop
Publikováno v:
Tetrahedron Letters. 60:147-149
A straightforward synthesis of isoindolinones has been developed via a [3 + 3] benzannulation of 4-arylmethylene-2,3-dioxopyrrolidines and 1,3-bissulfonylpropenes (or 4-sulfonylcrotonates). A series of functionalized isoindolinones were obtained in e
Publikováno v:
RSC Advances. 7:6660-6663
An asymmetric conjugate addition of t-butyl nitroacetate to in situ generated o-quinone methides had been developed. A chiral squamide derived from 9-amino-9-deoxyepiquinine was found to be the efficient catalyst. α-Nitro-β,β-diaryl-propionates co
Autor:
Jie, Liang, Yun-Xiang, Tang, Xiang-Zheng, Tang, Hua-Ju, Liang, Yamin, Gao, Cuiting, Fang, Tian-Yu, Zhang, Ming, Yan
Publikováno v:
Chemicalpharmaceutical bulletin. 67(4)
A series of meta-amido bromophenol derivatives were designed and synthesized. The compounds were found to potently inhibit the growth of Mycobacterium tuberculosis H37Ra. They also exhibited moderate inhibitory activity against Mycobacterium tubercul
Autor:
Ming Yan, Yong Zou, Xue-jing Zhang, Jie Liang, Lang Tong, Hua-Ju Liang, Albert S. C. Chan, Xiang-Zheng Tang
Publikováno v:
Organicbiomolecular chemistry. 16(19)
A base-mediated [3 + 3] benzannulation strategy for the conversion of 1,3-bis(sulfonyl)propenes and β,γ-unsaturated α-ketoesters to diaryl sulfones has been developed. This method provides facile, metal-free and efficient access to highly substitu