Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Xiang-Yang Zhong"'
Autor:
Xiang-Yang Zhong, Qian Du, Gourisankar Ghosh, Majid Ghassemian, Vivien Ya-Fan Wang, Daniel Kim, Yidan Li
Publikováno v:
Molecular cell, vol 67, iss 3
Summary Unlike prototypical IκB proteins, which are inhibitors of NF-κB RelA, cRel, and RelB dimers, the atypical IκB protein Bcl3 is primarily a transcriptional coregulator of p52 and p50 homodimers. Bcl3 exists as phospho-protein in many cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433fd01459a0fe6adba6a34665e8025c
https://escholarship.org/uc/item/8mp257bb
https://escholarship.org/uc/item/8mp257bb
Autor:
Suhyung Cho, Amy Hoang, Gourisankar Ghosh, Xiang-Yang Zhong, Xiang-Dong Fu, Rahul Sinha, Adrian R. Krainer
Publikováno v:
Proceedings of the National Academy of Sciences. 108:8233-8238
It has been widely accepted that the early spliceosome assembly begins with U1 small nuclear ribonucleoprotein (U1 snRNP) binding to the 5′ splice site (5′SS), which is assisted by the Ser/Arg (SR)-rich proteins in mammalian cells. In this proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ed8078a6cd4029aaa25531dd564941
https://doi.org/10.1073/pnas.1017700108
https://doi.org/10.1073/pnas.1017700108
Publikováno v:
Molecular Cell. 35:1-10
SR proteins have been studied extensively as a family of RNA-binding proteins that participate in both constitutive and regulated pre-mRNA splicing in mammalian cells. However, SR proteins were first discovered as factors that interact with transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4844617755b26792eb53b8ef123623a
https://doi.org/10.1016/j.molcel.2009.06.016
https://doi.org/10.1016/j.molcel.2009.06.016
Autor:
Joseph A. Adams, Gourisankar Ghosh, Jian-Hua Ding, James R. Feramisco, Jonathan C. Hagopian, Xiang-Dong Fu, Marissa M. Cruz, Xiang-Yang Zhong
Publikováno v:
Molecular Biology of the Cell. 17:876-885
Reversible phosphorylation of the SR family of splicing factors plays an important role in pre-mRNA processing in the nucleus. Interestingly, the SRPK family of kinases specific for SR proteins is localized in the cytoplasm, which is critical for nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c01535d0d46364eb65a3ab4c9dc6701
https://doi.org/10.1091/mbc.e05-10-0963
https://doi.org/10.1091/mbc.e05-10-0963
Autor:
Smarajit Polley, Arthur V. Hauenstein, Xiang-Yang Zhong, Amanda J. Fusco, Inder M. Verma, Don Vu, Tom Huxford, Youngchang Kim, De-Bin Huang, Gourisankar Ghosh, Alexander Hoffmann, Bärbel Schröfelbauer
Publikováno v:
PLoS biology, vol 11, iss 6
PLoS Biology
PLoS Biology, Vol 11, Iss 6, p e1001581 (2013)
PLoS Biology
PLoS Biology, Vol 11, Iss 6, p e1001581 (2013)
Conformational change in human IKK2 permits dimers to form higher-order oligomers that support interaction between kinase domains and promote activation through trans auto-phosphorylation.
Activation of the IκB kinase (IKK) is central to NF-κB
Activation of the IκB kinase (IKK) is central to NF-κB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b28481ce992483bb66e851b66b990e3
https://escholarship.org/uc/item/5mv5k6fm
https://escholarship.org/uc/item/5mv5k6fm
Publikováno v:
Genesdevelopment. 23(4)
Phosphorylation is essential for the SR family of splicing factors/regulators to function in constitutive and regulated pre-mRNA splicing; yet both hypo- and hyperphosphorylation of SR proteins are known to inhibit splicing, indicating that SR protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa89ae574fd5e37ab9ace3715803a1f
https://pubmed.ncbi.nlm.nih.gov/19240134
https://pubmed.ncbi.nlm.nih.gov/19240134
Autor:
Jun Wu, Jian‐Gang Wang, A. M. Abd El-Aty, Hong-Hao Zhou, Bing Zhu, Tong Li, Gan Zhou, Tian-Lun Yang, Xiang‐Yang Zhong, Dan Wang, Jie Liu, Lian-Sheng Wang
Publikováno v:
Clinical pharmacology and therapeutics. 75(3)
Objective St John's wort, an extract of the medicinal plant Hypericum perforatum, is widely used as an herbal antidepressant. Although the ability of St John's wort to induce cytochrome P450 (CYP) 3A4–mediated reaction has been well established, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e88f8e71aa24b1ec4e735a37f3c5aed
https://pubmed.ncbi.nlm.nih.gov/16198664
https://pubmed.ncbi.nlm.nih.gov/16198664
Publikováno v:
Genes & Development. 2/15/2009, Vol. 23 Issue 4, p482-495. 14p.
Autor:
Velazquez-Dones, Adolfo1,2, Hagopian, Jonatha C.1,3, Chen-Ting Ma3, Xiang-Yang Zhong1, Huulin Zhou1, Ghosh, Gourisankar2, Xiang-Dong Fu1 xdfu@ucsd.edu, Adams, Joseph A.3 joeadams@chem.ucsd.edu
Publikováno v:
Journal of Biological Chemistry. 12/16/2005, Vol. 280 Issue 50, p41761-41768. 8p. 5 Graphs.