Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Xiang-Xu Wang"'
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 4, Pp 200890- (2024)
Immunotherapy has transformed the management of hepatocellular carcinoma (HCC), but effectiveness varies among patients. This study aimed to identify biomarkers and HCC subtypes responsive to immunotherapy. Patients were classified into Immunity-High
Externí odkaz:
https://doaj.org/article/3623e587c437425b89ae3542e967d9ad
Autor:
Yuqi Yang, Sijia Wang, Xiang-xu Wang, Sen Guo, Huina Wang, Qiong Shi, Yangzi Tian, Hao Wang, Tao Zhao, Hengxiang Zhang, Baolu Zhang, Tianwen Gao, Chunying Li, Xiuli Yi, Weinan Guo
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Tumor cells frequently suffer from endoplasmic reticulum (ER) stress. Previous studies have extensively elucidated the role of tumorous unfolded protein response in melanoma cells, whereas the effect on tumor immunology and the un
Externí odkaz:
https://doaj.org/article/1ca35d42680d49a9a960322fc26ee89d
Autor:
Xiang-Xu Wang, Yun-Peng Liu, Yajie Lu, Li-Hong Wu, Jing-Yi Ren, Hongchen Ji, Xiaowen Wang, Hong-Mei Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe tertiary lymphatic structure (TLS) is an important component of the tumor immune microenvironment and has important significance in patient prognosis and response to immune therapy. However, the underlying mechanism of TLS in soft tissu
Externí odkaz:
https://doaj.org/article/5a450bf2b65e41f18207e58ca33e418b
Publikováno v:
Fayixue Zazhi, Vol 39, Iss 4, Pp 350-359 (2023)
Objective To investigate the characteristics and objective assessment method of visual field defects caused by optic chiasm and its posterior visual pathway injury. Methods Typical cases of visual field defects caused by injuries to the optic chiasm,
Externí odkaz:
https://doaj.org/article/df9b406057114c9489b37ea8582cf1f7
Autor:
Hongchen Ji, Qiong Zhang, Xiang-Xu Wang, Junjie Li, Xiaowen Wang, Wei Pan, Zhuochao Zhang, Ben Ma, Hong-Mei Zhang
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Purpose Pancreatic cancer is one of the deadliest cancers worldwide. The extracellular matrix (ECM) microenvironment affects the drug sensitivity and prognosis of pancreatic cancer patients. This study constructed an 8-genes pancreatic ECM s
Externí odkaz:
https://doaj.org/article/4ae004d4e9e848d6b220587919967df9
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
BackgroundGastric cancer (GC) is an aggressive malignant tumor with a high degree of heterogeneity, and its immune microenvironment is closely associated with tumor growth, development and drug resistance. Therefore, a classification system of gastri
Externí odkaz:
https://doaj.org/article/7cd2cc3afd7749a6a57e2386c96a419d
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 1387-1400 (2021)
Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression and play fundamental roles in immune regulation. Growing evidence suggests that immune-related genes and lncRNAs can serve as markers to predict the prognosis of pat
Externí odkaz:
https://doaj.org/article/33d778e44f4c4536b45e072f06514a99
Construction of m6A-based prognosis signature and prediction for immune and anti-angiogenic response
Autor:
Xiang-Xu Wang, Li-Hong Wu, Qiong-Yi Dou, Liping Ai, Yajie Lu, Shi-Zhou Deng, Qing-Qing Liu, Hongchen Ji, Hong-Mei Zhang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Background: Increasing evidence illustrated that m6A regulator-mediated modification plays a crucial role in regulating tumor immune and angiogenesis microenvironment. And the combination of immune checkpoint inhibitor and anti-angiogenic therapy has
Externí odkaz:
https://doaj.org/article/bbb4fea760e24c8887759dc9b4693de7
Autor:
Xiang-Xu Wang, Li-Hong Wu, Hongchen Ji, Qing-Qing Liu, Shi-Zhou Deng, Qiong-Yi Dou, Liping Ai, Wei Pan, Hong-Mei Zhang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Background: Copper metabolism plays an important role in the tumor microenvironment, and cuproptosis is the last discovered programmed cell death process. However, the potential mechanism of cuproptosis in regulating the immune microenvironment of HC
Externí odkaz:
https://doaj.org/article/33db32d1c16e49229c1d68c8574f45c6
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
Epstein–Barr virus (EBV)-associated gastric carcinoma (EBVaGC) is a specific molecular subtype of gastric carcinoma with a high proportion of tumor-infiltrating lymphocytes. It is a highly immunogenic tumor that may benefit from immunotherapy. Henc
Externí odkaz:
https://doaj.org/article/8ba3046b3490435b85f115e4f831a890