Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Xiang-Ru S. Xu"'
Autor:
Alessandro Zulli, Elana M. G. Chan, Bridgette Shelden, Dorothea Duong, Xiang-Ru S. Xu, Bradley J. White, Marlene K. Wolfe, Alexandria B. Boehm
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Candida auris is an emerging, multidrug-resistant fungal pathogen that poses a significant public health threat in healthcare settings. Despite yearly clinical cases rapidly increasing from 77 to 8,131 in the last decade, surveillance data o
Externí odkaz:
https://doaj.org/article/54f843391dd64a3784cd96246f089f2f
Autor:
Annabel Guichard, Tisha Haque, Marketta Bobik, Xiang-Ru S. Xu, Carissa Klanseck, Raja Babu Singh Kushwah, Mateus Berni, Bhagyashree Kaduskar, Valentino M. Gantz, Ethan Bier
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Gene-drives use CRISPR-Cas9 to be transmitted in a super-Mendelian fashion. Here the authors develop an allelic-drive for selective inheritance of a desired allele.
Externí odkaz:
https://doaj.org/article/d84a958ee4384c8680de46671dd3e198
Autor:
Carissa Klanseck, Sara Sanz Juste, Stephanie R. Heimler, Valentino M. Gantz, Ankush Auradkar, John M. Marshall, Emily A. Bulger, Anna Buchman, Ethan Bier, Lauren Ashley Miller, Omar S. Akbari, Sarah Leahy, Jared B. Bennett, Xiang-Ru S. Xu
Publikováno v:
Molecular cell. 80(2)
CRISPR-Cas9-based gene drive systems possess the inherent capacity to spread progressively throughout target populations. Here we describe two self-copying (or active) guide RNA-only genetic elements, called e-CHACRs and ERACRs. These elements use Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9882ff811857b71976cbbeaad51996b
https://pubmed.ncbi.nlm.nih.gov/32949493
https://pubmed.ncbi.nlm.nih.gov/32949493
Autor:
Bhagyashree Kaduskar, Valentino M. Gantz, Mateus Berni, Carissa Klanseck, Marketta Bobik, Xiang-Ru S. Xu, Ethan Bier, Raja Babu S. Kushwah, Tisha Haque, Annabel Guichard
Publikováno v:
Nature communications, vol 10, iss 1
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Gene-drive systems developed in several organisms result in super-Mendelian inheritance of transgenic insertions. Here, we generalize this “active genetic” approach to preferentially transmit allelic variants (allelic-drive) resulting from only a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1735e443dcb4944493ded30910d69cbc
https://doi.org/10.1038/s41467-019-09694-w
https://doi.org/10.1038/s41467-019-09694-w
Autor:
Kimberly L. Cooper, Gunnar Poplawski, Valentino M. Gantz, Ethan Bier, Hannah A. Grunwald, Xiang-Ru S. Xu
Publikováno v:
Nature
A gene drive biases the transmission of one of two copies of a gene such that it is inherited more frequently than by random segregation. Highly efficient gene drive systems were recently developed in insects, which leverage the sequence-targeted DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93216f12e79e4ffcb7dce9bf1edce35b
https://doi.org/10.1038/s41586-019-1861-4
https://doi.org/10.1038/s41586-019-1861-4
Autor:
Valentino M. Gantz, Gunnar Poplawski, Ethan Bier, Kimberly L. Cooper, Xiang-Ru S. Xu, Hannah A. Grunwald
Publikováno v:
Nature, vol 566, iss 7742
A gene drive biases the transmission of a particular allele of a gene such that it is inherited at a greater frequency than by random assortment. Recently, a highly efficient gene drive was developed in insects, which leverages the sequence-targeted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1978a596422ef32014e1e421a2427fd1
Autor:
Hannah A, Grunwald, Valentino M, Gantz, Gunnar, Poplawski, Xiang-Ru S, Xu, Ethan, Bier, Kimberly L, Cooper
Publikováno v:
Nature. 566(7742)
A gene drive biases the transmission of one of the two copies of a gene such that it is inherited more frequently than by random segregation. Highly efficient gene drive systems have recently been developed in insects, which leverage the sequence-tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::053c873f521ff789a16a3973439b1841
https://pubmed.ncbi.nlm.nih.gov/31911657
https://pubmed.ncbi.nlm.nih.gov/31911657
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
The knirps (kni) locus encodes transcription factors required for induction of the L2 wing vein in Drosophila. Here, we employ diverse CRISPR/Cas9 genome editing tools to generate a series of targeted lesions within the endogenous cis-regulatory modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e5c8868f86ffeaf8588c492ddaf90a
https://doi.org/10.7554/elife.30281
https://doi.org/10.7554/elife.30281