Zobrazeno 1 - 10
of 536
pro vyhledávání: '"Xiang-Jiao Yang"'
Publikováno v:
iScience, Vol 20, Iss , Pp 148-167 (2019)
Summary: We report that cerebrum-specific inactivation of the histone deacetylase 3 (HDAC3) gene causes striking developmental defects in the neocortex, hippocampus, and corpus callosum; post-weaning lethality; and abnormal behaviors, including hyper
Externí odkaz:
https://doaj.org/article/bd58db4b104347f0b7002657beb42087
Autor:
Emma Wakeling, Meriel McEntagart, Michael Bruccoleri, Charles Shaw-Smith, Karen L. Stals, Matthew Wakeling, Angela Barnicoat, Clare Beesley, Andrea K. Hanson-Kahn, Mary Kukolich, David A. Stevenson, Philippe M. Campeau, Sian Ellard, Sarah H. Elsea, Xiang-Jiao Yang, Richard C. Caswell
Publikováno v:
HGG Advances, Vol 2, Iss 1, Pp 100015- (2021)
Summary: Histone deacetylases play crucial roles in the regulation of chromatin structure and gene expression in the eukaryotic cell, and disruption of their activity causes a wide range of developmental disorders in humans. Loss-of-function alleles
Externí odkaz:
https://doaj.org/article/246a7dacb117428c8733e2f639e82ae3
Autor:
Linya You, Kezhi Yan, Jinfeng Zou, Hong Zhao, Nicholas R Bertos, Morag Park, Edwin Wang, Xiang-Jiao Yang
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005329 (2015)
Externí odkaz:
https://doaj.org/article/2df2f845a5774d0d8bcb2e7f05e0d98e
Autor:
Linya You, Kezhi Yan, Jinfeng Zou, Hong Zhao, Nicholas R Bertos, Morag Park, Edwin Wang, Xiang-Jiao Yang
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005034 (2015)
Lysine acetylation has recently emerged as an important post-translational modification in diverse organisms, but relatively little is known about its roles in mammalian development and stem cells. Bromodomain- and PHD finger-containing protein 1 (BR
Externí odkaz:
https://doaj.org/article/21ae3b8be50d401aa8f73d4659278dbc
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93864 (2014)
The epigenetic regulator Bmi1 is key in haematopoietic stem cells, and its inactivation leads to defects in haematopoiesis. Parathyroid hormone (PTH), an important modulator of bone homeostasis, also regulates haematopoiesis, so we asked whether PTH
Externí odkaz:
https://doaj.org/article/452ad69237bc4ae6af1fdf29e56f6edc
Publikováno v:
International Journal of Cell Biology, Vol 2010 (2010)
Healthy lifestyles and environment produce a good state of health. A number of scientific studies support the notion that external stimuli regulate an individual's epigenomic profile. Epigenetic changes play a key role in defining gene expression pat
Externí odkaz:
https://doaj.org/article/67d1bad6e8934065b0002337f9d493f7
Publikováno v:
Current Protocols. 3
Autor:
Xiang-Jiao Yang
Disclaimer statementThe authors have withdrawn this manuscript because an issue was raised about the SARS- COV-2 genome sequence data used in the study. Therefore, the authors do not wish this work to be cited as reference for the project. If you hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abbc2189f197f409ea689dbeeb17a61f
https://doi.org/10.1101/2022.03.15.484404
https://doi.org/10.1101/2022.03.15.484404
Autor:
Philippe M. Campeau, Gabrielle Lemire, Smrithi Salian, Thomas Garcia, Stylianos E. Antonarakis, Sophie Ehresmann, Seth I. Berger, Justine Rousseau, Sylviane Hanquinet, Armand Bottani, Xiang-Jiao Yang, Jacques Côté, Ann C.M. Smith, Jonathan Humbert, Jennifer Heeley, Rami Alasiri, Erin Beaver, Periklis Makrythanasis
Publikováno v:
Am J Hum Genet
American Journal of Human Genetics, Vol. 107, No 3 (2020) pp. 564-574
American Journal of Human Genetics, Vol. 107, No 3 (2020) pp. 564-574
KAT5 encodes an essential lysine acetyltransferase, previously called TIP60, which is involved in regulating gene expression, DNA repair, chromatin remodeling, apoptosis, and cell proliferation; but it remains unclear whether variants in this gene ca
Autor:
Xiang-Jiao Yang
{delta} variant has rapidly become the predominant pandemic driver and yielded four subvariants ({delta}1, {delta}2, {delta}3 and {delta}4). Among them, {delta}1 has been mainly responsible for the latest COVID-19 waves in India, Southeast Asia, Euro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7193f8091dca7111dce82b06953bbf81
https://doi.org/10.1101/2021.11.01.21265445
https://doi.org/10.1101/2021.11.01.21265445