Zobrazeno 1 - 10
of 549
pro vyhledávání: '"Xiang Zhai"'
Autor:
Baoxiang Chen, Yanrong Deng, Yuntian Hong, Lifang Fan, Xiang Zhai, Heng Hu, Siyuan Yin, Quanjiao Chen, Xiaoyu Xie, Xianghai Ren, Jianhong Zhao, Congqing Jiang
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract The RNA modification, 5‐methylcytosine (m5C), has recently gained prominence as a pivotal post‐transcriptional regulator of gene expression, intricately intertwined with various tumorigenic processes. However, the exact mechanisms govern
Externí odkaz:
https://doaj.org/article/8571c9db05ef4a2ebf43a3af3bc84355
Autor:
Xiang Zhai, Baoxiang Chen, Heng Hu, Yanrong Deng, Yazhu Chen, Yuntian Hong, Xianghai Ren, Congqing Jiang
Publikováno v:
Cancer Medicine, Vol 13, Iss 10, Pp n/a-n/a (2024)
Abstract Background Tumors that resist anoikis, a programmed cell death triggered by detachment from the extracellular matrix, promote metastasis; however, the role of anoikis‐related genes (ARGs) in colorectal cancer (CRC) stratification, prognosi
Externí odkaz:
https://doaj.org/article/a780b6070f1e40c08c4881dafc4db43a
Autor:
Baoxiang Chen, Yuntian Hong, Xiang Zhai, Yanrong Deng, Heng Hu, Shunhua Tian, Yukang Zhang, Xianghai Ren, Jianhong Zhao, Congqing Jiang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-14 (2023)
Abstract Cancer immunotherapy is arguably the most rapidly advancing realm of cancer treatment. Glutathione peroxidase 4 (GPX4) has emerged as the vital enzyme to prevent lipid peroxidation and maintain cellular redox homeostasis. However, the mechan
Externí odkaz:
https://doaj.org/article/c4addafe79d04011955e96329094df70
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Colorectal cancer (CRC) is one of the most common malignant cancers worldwide and seriously threatens human health. The clustered regulatory interspaced short palindromic repeat/CRISPR-associate nuclease 9 (CRISPR/Cas9) system is an adaptive
Externí odkaz:
https://doaj.org/article/88845a91cba64349be0c9c16e68ff4e1
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Real-time quantitative polymerase chain reaction (RT-qPCR) is the most common method to determine mRNA expression, and Minimum Information for Publication of RT-qPCR Experiments (MIQE) proposes that a panel of reference genes for RT-qPCR is
Externí odkaz:
https://doaj.org/article/10f4752c1fef4425b3b80728c6701cb9
Autor:
Bharath Srinivasan, Juan Daniel Flórez Weidinger, Xiang Zhai, Guillaume Lemercier, Timothy Ikeda, Mark Brewer, Bairu Zhang, Stephan Heyse, Jonathan Wingfield, Stephan Steigele
Publikováno v:
SLAS Discovery, Vol 27, Iss 8, Pp 460-470 (2022)
Recent efforts for increasing the success in drug discovery focus on an early, massive, and routine mechanistic and/or kinetic characterization of drug-target engagement as part of a design-make-test-analyze strategy. From an experimental perspective
Externí odkaz:
https://doaj.org/article/a2126a1a1f8f429598c4f15e9ed9a831
Autor:
Baoxiang Chen, Yuntian Hong, Rui Gui, Huabin Zheng, Shunhua Tian, Xiang Zhai, Xiaoyu Xie, Quanjiao Chen, Qun Qian, Xianghai Ren, Lifang Fan, Congqing Jiang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-16 (2022)
Abstract Circular RNAs (circRNAs) are a recently discovered kind of regulatory RNAs that have emerged as critical biomarkers of various types of cancers. Metabolic reprogramming has gradually been identified as a distinct hallmark of cancer cells. Th
Externí odkaz:
https://doaj.org/article/25466033aeb14f5e960cb498db580393
Autor:
Xiang Zhai, Xin-yang Li, Yu-jing Wang, Ke-ru Qin, Jin-rui Hu, Mei-ning Li, Hai-long Wang, Rui Guo
Publikováno v:
Endocrinology and Metabolism, Vol 37, Iss 3, Pp 533-546 (2022)
Background It is well-established that serum testosterone in men decreases with age, yet the underlying mechanism of this change remains elusive. Methods The expression patterns of Fancd2 opposite-strand (Fancd2os) in BALB/c male mice and testicular
Externí odkaz:
https://doaj.org/article/8b3b7c18d37f424390ae99972b50eed8
Publikováno v:
Asian Journal of Surgery, Vol 46, Iss 5, Pp 2128-2129 (2023)
Externí odkaz:
https://doaj.org/article/db39c21f146e40c8a50d7b56c0fcdc72
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
Colorectal cancer (CRC) is a common malignancy worldwide, and the gut microbiota and metabolites play an important role in its initiation and progression. In this study, we constructed a mouse model of inflammation-induced colorectal tumors, with fix
Externí odkaz:
https://doaj.org/article/6a83299b904f41009f45fa0cd8bc6026